English
Related papers

Related papers: Beyond Learning on Molecules by Weakly Supervising…

200 papers

In the majority of molecular optimization tasks, predictive machine learning (ML) models are limited due to the unavailability and cost of generating big experimental datasets on the specific task. To circumvent this limitation, ML models…

Publicly available collections of drug-like molecules have grown to comprise 10s of billions of possibilities in recent history due to advances in chemical synthesis. Traditional methods for identifying "hit" molecules from a large…

Understanding and designing biomolecules, such as proteins and small molecules, is central to advancing drug discovery, synthetic biology and enzyme engineering. Recent breakthroughs in artificial intelligence have revolutionized…

Computation and Language · Computer Science 2025-07-28 Xiang Zhuang , Keyan Ding , Tianwen Lyu , Yinuo Jiang , Xiaotong Li , Zhuoyi Xiang , Zeyuan Wang , Ming Qin , Kehua Feng , Jike Wang , Qiang Zhang , Huajun Chen

Humans are excellent at understanding language and vision to accomplish a wide range of tasks. In contrast, creating general instruction-following embodied agents remains a difficult challenge. Prior work that uses pure language-only models…

Computer Vision and Pattern Recognition · Computer Science 2023-03-28 Hao Liu , Lisa Lee , Kimin Lee , Pieter Abbeel

The answers to many unsolved problems lie in the intractable chemical space of molecules and materials. Machine learning techniques are rapidly growing in popularity as a way to compress and explore chemical space efficiently. One of the…

Chemical Physics · Physics 2020-01-06 John E. Herr , Kevin Koh , Kun Yao , John Parkhill

Visual embedding models excel at zero-shot tasks like visual retrieval and classification. However, these models cannot be used for tasks that contain ambiguity or require user instruction. These tasks necessitate an embedding model which…

Computer Vision and Pattern Recognition · Computer Science 2025-08-22 Benjamin Schneider , Florian Kerschbaum , Wenhu Chen

Machine learning (ML) offers considerable promise for the design of new molecules and materials. In real-world applications, the design problem is often domain-specific, and suffers from insufficient data, particularly labeled data, for ML…

Chemical Physics · Physics 2025-02-04 Ming Han , Ge Sun , Juan J. de Pablo

People can recognize scenes across many different modalities beyond natural images. In this paper, we investigate how to learn cross-modal scene representations that transfer across modalities. To study this problem, we introduce a new…

Computer Vision and Pattern Recognition · Computer Science 2016-07-26 Lluis Castrejon , Yusuf Aytar , Carl Vondrick , Hamed Pirsiavash , Antonio Torralba

Multiple modalities often co-occur when describing natural phenomena. Learning a joint representation of these modalities should yield deeper and more useful representations. Previous generative approaches to multi-modal input either do not…

Machine Learning · Computer Science 2018-11-13 Mike Wu , Noah Goodman

Large language models (LLMs) have demonstrated broad utility across molecular domains, spanning drug discovery and materials design. Analyzing LLMs' latent representations is crucial for elucidating their underlying mechanisms, improving…

Machine Learning · Computer Science 2026-02-03 Zhuoran Li , Xu Sun , Wanyu Lin , Jiannong Cao

A feature learning task involves training models that are capable of inferring good representations (transformations of the original space) from input data alone. When working with limited or unlabelled data, and also when multiple visual…

Computer Vision and Pattern Recognition · Computer Science 2018-11-02 Gabriel B. Cavallari , Leonardo Sampaio Ferraz Ribeiro , Moacir Antonelli Ponti

Unsupervised learning of vision transformers seeks to pretrain an encoder via pretext tasks without labels. Among them is the Masked Image Modeling (MIM) aligned with pretraining of language transformers by predicting masked patches as a…

Computer Vision and Pattern Recognition · Computer Science 2023-03-15 Xiao Wang , Ying Wang , Ziwei Xuan , Guo-Jun Qi

The ability of machine learning models to store input information in hidden layer vector embeddings, analogous to the concept of `memory', is widely employed but not well characterized. We find that language model embeddings typically…

Computation and Language · Computer Science 2026-05-20 Benjamin L. Badger

Recent advances in representation learning have demonstrated an ability to represent information from different modalities such as video, text, and audio in a single high-level embedding vector. In this work we present a self-supervised…

Computer Vision and Pattern Recognition · Computer Science 2021-06-11 Alexander H. Liu , SouYoung Jin , Cheng-I Jeff Lai , Andrew Rouditchenko , Aude Oliva , James Glass

Meta-learning has become a practical approach towards few-shot image classification, where "a strategy to learn a classifier" is meta-learned on labeled base classes and can be applied to tasks with novel classes. We remove the requirement…

Computer Vision and Pattern Recognition · Computer Science 2022-06-10 Han-Jia Ye , Lu Han , De-Chuan Zhan

Masked Image Modeling (MIM) achieves outstanding success in self-supervised representation learning. Unfortunately, MIM models typically have huge computational burden and slow learning process, which is an inevitable obstacle for their…

Computer Vision and Pattern Recognition · Computer Science 2023-03-10 Haoqing Wang , Yehui Tang , Yunhe Wang , Jianyuan Guo , Zhi-Hong Deng , Kai Han

Transformers have become methods of choice in many applications thanks to their ability to represent complex interactions between elements. However, extending the Transformer architecture to non-sequential data such as molecules and…

Machine Learning · Computer Science 2022-04-27 Yoni Choukroun , Lior Wolf

We present $\textbf{MolT5}$ $-$ a self-supervised learning framework for pretraining models on a vast amount of unlabeled natural language text and molecule strings. $\textbf{MolT5}$ allows for new, useful, and challenging analogs of…

Computation and Language · Computer Science 2022-11-07 Carl Edwards , Tuan Lai , Kevin Ros , Garrett Honke , Kyunghyun Cho , Heng Ji

The natural world is abundant with concepts expressed via visual, acoustic, tactile, and linguistic modalities. Much of the existing progress in multimodal learning, however, focuses primarily on problems where the same set of modalities…

Machine Learning · Computer Science 2020-12-08 Paul Pu Liang , Peter Wu , Liu Ziyin , Louis-Philippe Morency , Ruslan Salakhutdinov

Prior works have demonstrated that implicit representations trained only for reconstruction tasks typically generate encodings that are not useful for semantic tasks. In this work, we propose a method that contextualises the encodings of…

Computer Vision and Pattern Recognition · Computer Science 2023-05-23 Theo W. Costain , Kejie Li , Victor A. Prisacariu