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Quality molecular representations are key to foundation model development in bio-medical research. Previous efforts have typically focused on a single representation or molecular view, which may have strengths or weaknesses on a given task.…

Magnetic Resonance Imaging (MRI) typically recruits multiple sequences (defined here as "modalities"). As each modality is designed to offer different anatomical and functional clinical information, there are evident disparities in the…

Image and Video Processing · Electrical Eng. & Systems 2022-03-09 Chengjia Wang , Guang Yang , Giorgos Papanastasiou

Multimodal MRI provides complementary and clinically relevant information to probe tissue condition and to characterize various diseases. However, it is often difficult to acquire sufficiently many modalities from the same subject due to…

Image and Video Processing · Electrical Eng. & Systems 2021-06-08 Xiaofeng Liu , Fangxu Xing , Georges El Fakhri , Jonghye Woo

Foundation models constitute a significant advancement in computer vision: after a single, albeit costly, training phase, they can address a wide array of tasks. In the field of Earth observation, over 75 remote sensing vision foundation…

Computer Vision and Pattern Recognition · Computer Science 2025-05-07 Pierre Adorni , Minh-Tan Pham , Stéphane May , Sébastien Lefèvre

Multimodal Magnetic Resonance Imaging (MRI) provides essential complementary information for analyzing brain tumor subregions. While methods using four common MRI modalities for automatic segmentation have shown success, they often face…

Image and Video Processing · Electrical Eng. & Systems 2024-11-14 Runze Cheng , Zhongao Sun , Ye Zhang , Chun Li

Foundation models provide robust embeddings for diverse tasks, including medical imaging. We evaluate embeddings from seven general and medical-specific foundation models (e.g., DenseNet121, BiomedCLIP, MedImageInsight, Rad-DINO,…

Foundation models have recently attracted significant attention for their impressive generalizability across diverse downstream tasks. However, these models are demonstrated to exhibit great limitations in representing high-frequency…

Image and Video Processing · Electrical Eng. & Systems 2025-04-18 Yuetan Chu , Yilan Zhang , Zhongyi Han , Changchun Yang , Longxi Zhou , Gongning Luo , Chao Huang , Xin Gao

Understanding neural activity and information representation is crucial for advancing knowledge of brain function and cognition. Neural activity, measured through techniques like electrophysiology and neuroimaging, reflects various aspects…

Neurons and Cognition · Quantitative Biology 2024-07-22 Fengyu Yang , Chao Feng , Daniel Wang , Tianye Wang , Ziyao Zeng , Zhiyang Xu , Hyoungseob Park , Pengliang Ji , Hanbin Zhao , Yuanning Li , Alex Wong

Multimodal deep learning has shown strong potential in medical applications by integrating heterogeneous data sources such as medical images and structured clinical variables. However, most existing approaches implicitly assume complete…

Machine Learning · Computer Science 2026-05-13 Camillo Maria Caruso , Valerio Guarrasi , Paolo Soda

Positron emission tomography (PET) scans expose patients to radiation, which can be mitigated by reducing the dose, albeit at the cost of diminished quality. This makes low-dose (LD) PET recovery an active research area. Previous studies…

Image and Video Processing · Electrical Eng. & Systems 2026-03-11 Ghulam Nabi Ahmad Hassan Yar , Himashi Peiris , Victoria Mar , Cameron Dennis Pain , Zhaolin Chen

Medical image segmentation supports clinical workflows by precisely delineating anatomical structures and lesions. However, medical image datasets medical image datasets suffer from acquisition noise and annotation ambiguity, causing…

Artificial Intelligence · Computer Science 2026-04-14 Ruiyang Li , Fang Liu , Licheng Jiao , Xinglin Xie , Jiayao Hao , Shuo Li , Xu Liu , Jingyi Yang , Lingling Li , Puhua Chen , Wenping Ma

Large AI models have been widely adopted in wireless communications for channel modeling, beamforming, and resource optimization. However, most existing efforts remain limited to single-modality inputs and channel-specific objec- tives,…

Machine Learning · Computer Science 2025-11-18 Zhizhen Li , Xuanhao Luo , Xueren Ge , Longyu Zhou , Xingqin Lin , Yuchen Liu

Anomaly detection in medical images is an important yet challenging task due to the diversity of possible anomalies and the practical impossibility of collecting comprehensively annotated data sets. In this work, we tackle unsupervised…

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This paper introduces the DeepATLAS foundational model for localization tasks in the domain of high-dimensional biomedical data. Upon convergence of the proposed self-supervised objective, a pretrained model maps an input to an…

Computer Vision and Pattern Recognition · Computer Science 2024-02-16 Peter D. Chang

Medical image retrieval is essential for clinical decision-making and translational research, relying on discriminative visual representations. Yet, current methods remain fragmented, relying on separate architectures and training…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Che Liu , Zheng Jiang , Chengyu Fang , Heng Guo , Yan-Jie Zhou , Jiaqi Qu , Le Lu , Minfeng Xu

Multi-modality is widely used in medical imaging, because it can provide multiinformation about a target (tumor, organ or tissue). Segmentation using multimodality consists of fusing multi-information to improve the segmentation. Recently,…

Image and Video Processing · Electrical Eng. & Systems 2020-07-17 Tongxue Zhou , Su Ruan , Stéphane Canu

The deep learning field is converging towards the use of general foundation models that can be easily adapted for diverse tasks. While this paradigm shift has become common practice within the field of natural language processing, progress…

Computer Vision and Pattern Recognition · Computer Science 2023-11-15 Joana Palés Huix , Adithya Raju Ganeshan , Johan Fredin Haslum , Magnus Söderberg , Christos Matsoukas , Kevin Smith

Cardiac magnetic resonance imaging (CMR), considered the gold standard for noninvasive cardiac assessment, is a diverse and complex modality requiring a wide variety of image processing tasks for comprehensive assessment of cardiac…

Image and Video Processing · Electrical Eng. & Systems 2025-12-03 Athira J Jacob , Indraneel Borgohain , Teodora Chitiboi , Puneet Sharma , Dorin Comaniciu , Daniel Rueckert

Finetuning pretrained models occurs in a low-dimensional subspace of the full parameter space. Prior work has focused on characterizing this optimization subspace, but largely ignored the complementary question: why do certain directions…

Machine Learning · Computer Science 2026-05-11 Junjie Yu , Yue Wang , Zihan Deng , Yan Zhu , Wenxiao Ma , Quanying Liu

Multimodal foundation models have significantly improved feature representation by integrating information from multiple modalities, making them highly suitable for a broader set of applications. However, the exploration of multimodal…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Kaiwen Zheng , Xuri Ge , Junchen Fu , Jun Peng , Joemon M. Jose