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Loss of cortical integration and changes in the dynamics of electrophysiological brain signals characterize the transition from wakefulness towards unconsciousness. The common mechanism underlying these observations remains unknown. In this…

Ever since the advent of the neuron doctrine more than a century ago, information processing in the brain is widely believed to mainly follow the forward pre to post-synaptic neurons direction. Challenging this prevalent view, in this…

Neurons and Cognition · Quantitative Biology 2021-09-15 Zied Ben Houidi

Humans and most animals inherently possess a distinctive capacity to continually acquire novel experiences and accumulate worldly knowledge over time. This ability, termed continual learning, is also critical for deep neural networks (DNNs)…

Machine Learning · Computer Science 2025-04-22 Geng Liu , Fei Zhu , Rong Feng , Zhiqiang Yi , Shiqi Wang , Gaofeng Meng , Zhaoxiang Zhang

All varieties of dreaming remain a mystery. Lucid dreams in particular, or those characterized by awareness of the dream, are notoriously difficult to study. Their scarce prevalence and resistance to deliberate induction make it difficult…

Computation and Language · Computer Science 2026-03-31 Remington Mallett

Despite substantial research into the biological basis of memory, the precise mechanisms by which experiences are encoded, stored, and retrieved in the brain remain incompletely understood. A growing body of evidence supports the engram…

Neural and Evolutionary Computing · Computer Science 2025-10-28 Daniel Szelogowski

Sleep is one of the most noticeable and widespread phenomena occurring in multicellular animals. Nevertheless, no consensus for a theory of its origins has emerged. In particular, no explicit, quantitative theory exists that elucidates or…

Other Quantitative Biology · Quantitative Biology 2007-05-23 Van M. Savage , Geoffrey B. West

We all are fascinated by the phenomena of intelligent behavior, as generated both by our own brains and by the brains of other animals. As physicists we would like to understand if there are some general principles that govern the structure…

Biological Physics · Physics 2007-05-23 William Bialek

It has become increasingly popular to study the brain as a network due to the realization that functionality cannot be explained exclusively by independent activation of specialized regions. Instead, across a large spectrum of behaviors,…

Neurons and Cognition · Quantitative Biology 2014-07-22 Petko Bogdanov , Nazli Dereli , Danielle S. Bassett , Scott T. Grafton , Ambuj K. Singh

Humans excel at continually acquiring, consolidating, and retaining information from an ever-changing environment, whereas artificial neural networks (ANNs) exhibit catastrophic forgetting. There are considerable differences in the…

Neural and Evolutionary Computing · Computer Science 2023-04-17 Fahad Sarfraz , Elahe Arani , Bahram Zonooz

For long it has been known that specific patterns of folding are necessary for an optimally functioning brain. For instance, lissencephaly and polymicrogyria can lead to severe mental retardation, short life expectancy, epileptic seizures,…

Biological Physics · Physics 2020-04-03 Lucas da Costa Campos , Raphael Hornung , Gerhard Gompper , Jens Elgeti , Svenja Caspers

Mounting evidence in neuroscience suggests the possibility of neuronal representations that individual neurons serve as the substrates of different mental representations in a point-to-point way. Combined with associationism, it can…

Neurons and Cognition · Quantitative Biology 2021-09-06 Chiyin Zheng

Several guiding principles for thought processes are proposed and a neural-network-type model implementing these principles is presented and studied. We suggest to consider thinking within an associative network built-up of overlapping…

Neurons and Cognition · Quantitative Biology 2007-05-23 Claudius Gros

Consciousness is presented not as a unified and uniquely human characteristic, but rather as an emergent property of several building blocks, most of which are demonstrably present in other species. Each block has its own rationale under…

Physics and Society · Physics 2024-05-13 Robin W. Spencer

Sleep is a complex physiological process evaluated through various modalities recording electrical brain, cardiac, and respiratory activities. We curate a large polysomnography dataset from over 14,000 participants comprising over 100,000…

Machine Learning · Computer Science 2024-05-29 Rahul Thapa , Bryan He , Magnus Ruud Kjaer , Hyatt Moore , Gauri Ganjoo , Emmanuel Mignot , James Zou

Complementary Learning Systems theory holds that intelligent agents need two learning systems. Semantic memory is encoded in the neocortex with dense, overlapping representations and acquires structured knowledge. Episodic memory is encoded…

Machine Learning · Computer Science 2025-09-03 Lucie Fontaine , Frédéric Alexandre

Replay in the brain has been viewed as rehearsal, or, more recently, as sampling from a transition model. Here, we propose a new hypothesis: that replay is able to implement a form of compositional computation where entities are assembled…

Neurons and Cognition · Quantitative Biology 2022-12-21 Zeb Kurth-Nelson , Timothy Behrens , Greg Wayne , Kevin Miller , Lennart Luettgau , Ray Dolan , Yunzhe Liu , Philipp Schwartenbeck

Recently a daily routine for associative neural networks has been proposed: the network Hebbian-learns during the awake state (thus behaving as a standard Hopfield model), then, during its sleep state, optimizing information storage, it…

Disordered Systems and Neural Networks · Physics 2020-01-29 Elena Agliari , Francesco Alemanno , Adriano Barra , Alberto Fachechi

The relationship between brain structure and function has been probed using a variety of approaches, but how the underlying structural connectivity of the human brain drives behavior is far from understood. To investigate the effect of…

Neurons and Cognition · Quantitative Biology 2018-11-15 Kanika Bansal , John D. Medaglia , Danielle S. Bassett , Jean M. Vettel , Sarah F. Muldoon

Over the last few years, research in automatic sleep scoring has mainly focused on developing increasingly complex deep learning architectures. However, recently these approaches achieved only marginal improvements, often at the expense of…

Neurons in the visual cortex are correlated in their variability. The presence of correlation impacts cortical processing because noise cannot be averaged out over many neurons. In an effort to understand the functional purpose of…

Machine Learning · Computer Science 2018-04-04 Shamak Dutta , Bryan Tripp , Graham Taylor