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Extracting relevant information from data is crucial for all forms of learning. The information bottleneck (IB) method formalizes this, offering a mathematically precise and conceptually appealing framework for understanding learning…

Machine Learning · Computer Science 2021-10-27 Vudtiwat Ngampruetikorn , David J. Schwab

Markov state models (MSMs) are valuable for studying dynamics of protein conformational changes via statistical analysis of molecular dynamics (MD) simulations. In MSMs, the complex configuration space is coarse-grained into conformational…

Biological Physics · Physics 2024-06-11 Dedi Wang , Yunrui Qiu , Eric Beyerle , Xuhui Huang , Pratyush Tiwary

Generative modeling becomes increasingly data-intensive in high-dimensional spaces. In molecular science, where data collection is expensive and important events are rare, compression to lower-dimensional manifolds is especially important…

Machine Learning · Computer Science 2025-10-14 Richard John , Yunrui Qiu , Lukas Herron , Pratyush Tiwary

Markov processes are widely used mathematical models for describing dynamic systems in various fields. However, accurately simulating large-scale systems at long time scales is computationally expensive due to the short time steps required…

Machine Learning · Computer Science 2024-01-29 Marco Federici , Patrick Forré , Ryota Tomioka , Bastiaan S. Veeling

Most works studying representation learning focus only on classification and neglect regression. Yet, the learning objectives and, therefore, the representation topologies of the two tasks are fundamentally different: classification targets…

Machine Learning · Computer Science 2024-05-17 Shihao Zhang , kenji kawaguchi , Angela Yao

The development of diagnostic models is gaining traction in the field of psychiatric disorders. Recently, machine learning classifiers based on resting-state functional magnetic resonance imaging (rs-fMRI) have been developed to identify…

Machine Learning · Computer Science 2025-10-06 Tianzheng Hu , Qiang Li , Shu Liu , Vince D. Calhoun , Guido van Wingen , Shujian Yu

The problem of distributed representation learning is one in which multiple sources of information $X_1,\ldots,X_K$ are processed separately so as to learn as much information as possible about some ground truth $Y$. We investigate this…

Machine Learning · Statistics 2019-04-02 Inaki Estella Aguerri , Abdellatif Zaidi

Numerous deep learning algorithms have been inspired by and understood via the notion of information bottleneck, where unnecessary information is (often implicitly) minimized while task-relevant information is maximized. However, a rigorous…

Machine Learning · Computer Science 2023-05-31 Kenji Kawaguchi , Zhun Deng , Xu Ji , Jiaoyang Huang

Deep neural networks (DNNs) have demonstrated remarkable performance across various domains, but their inherent complexity makes them challenging to interpret. This is especially true for temporal graph regression tasks due to the complex…

Machine Learning · Computer Science 2025-12-30 Ali Royat , Seyed Mohamad Moghadas , Lesley De Cruz , Adrian Munteanu

The ever-increasing parameter counts of deep learning models necessitate effective compression techniques for deployment on resource-constrained devices. This paper explores the application of information geometry, the study of…

Machine Learning · Computer Science 2025-07-15 Zakhar Shumaylov , Vasileios Tsiaras , Yannis Stylianou

This paper investigates task-oriented communication for edge inference, where a low-end edge device transmits the extracted feature vector of a local data sample to a powerful edge server for processing. It is critical to encode the data…

Signal Processing · Electrical Eng. & Systems 2023-01-19 Jiawei Shao , Yuyi Mao , Jun Zhang

Contrastive Language-Image Pretraining (CLIP) has achieved remarkable success in cross-modal tasks such as zero-shot image classification and text-image retrieval by effectively aligning visual and textual representations. However, the…

Computer Vision and Pattern Recognition · Computer Science 2025-04-01 Yingrui Ji , Xi Xiao , Gaofei Chen , Hao Xu , Chenrui Ma , Lijing Zhu , Aokun Liang , Jiansheng Chen

Graph Neural Networks (GNNs) have shown promising results on a broad spectrum of applications. Most empirical studies of GNNs directly take the observed graph as input, assuming the observed structure perfectly depicts the accurate and…

Machine Learning · Computer Science 2021-12-17 Qingyun Sun , Jianxin Li , Hao Peng , Jia Wu , Xingcheng Fu , Cheng Ji , Philip S. Yu

Integration of data from multiple omics techniques is becoming increasingly important in biomedical research. Due to non-uniformity and technical limitations in omics platforms, such integrative analyses on multiple omics, which we refer to…

Machine Learning · Computer Science 2021-02-11 Changhee Lee , Mihaela van der Schaar

Collaborative perception systems leverage multiple edge devices, such surveillance cameras or autonomous cars, to enhance sensing quality and eliminate blind spots. Despite their advantages, challenges such as limited channel capacity and…

Networking and Internet Architecture · Computer Science 2025-01-07 Zhengru Fang , Senkang Hu , Jingjing Wang , Yiqin Deng , Xianhao Chen , Yuguang Fang

Developing interpretable models for neurodevelopmental disorders (NDDs) diagnosis presents significant challenges in effectively encoding, decoding, and integrating multimodal neuroimaging data. While many existing machine learning…

Computer Vision and Pattern Recognition · Computer Science 2026-04-24 Yueyang Li , Lei Chen , Wenhao Dong , Shengyu Gong , Zijian Kang , Boyang Wei , Weiming Zeng , Hongjie Yan , Lingbin Bian , Zhiguo Zhang , Wai Ting Siok , Nizhuan Wang

The information bottleneck (IB) method aims to find compressed representations of a variable $X$ that retain the most relevant information about a target variable $Y$. We show that for a wide family of distributions -- namely, when $Y$ is…

Information Theory · Computer Science 2023-10-09 Etam Benger , Shahab Asoodeh , Jun Chen

Encoding only the task-related information from the raw data, \ie, disentangled representation learning, can greatly contribute to the robustness and generalizability of models. Although significant advances have been made by regularizing…

Computer Vision and Pattern Recognition · Computer Science 2024-08-15 Zhuohang Dang , Minnan Luo , Chengyou Jia , Guang Dai , Jihong Wang , Xiaojun Chang , Jingdong Wang

Based on the notion of information bottleneck (IB), we formulate a quantization problem called "IB quantization". We show that IB quantization is equivalent to learning based on the IB principle. Under this equivalence, the standard neural…

Machine Learning · Computer Science 2019-02-13 Hongyu Guo , Yongyi Mao , Ali Al-Bashabsheh , Richong Zhang

Recent pre-training strategies for molecular graphs have attempted to use 2D and 3D molecular views as both inputs and self-supervised signals, primarily aligning graph-level representations. However, existing studies remain limited in…

Machine Learning · Computer Science 2025-11-25 Van Thuy Hoang , O-Joun Lee