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Brain Foundation Models (BFMs) are transforming neuroscience by enabling scalable and transferable learning from neural signals, advancing both clinical diagnostics and cutting-edge neuroscience exploration. Their emergence is powered by…

Machine Learning · Computer Science 2026-02-13 Fanqi Shen , Enhong Yang , Jiahe Li , Junru Hong , Xiaoran Pan , Zhizhang Yuan , Meng Li , Yang Yang

Foundation Models (FMs) are large-scale, pre-trained artificial intelligence (AI) systems that have revolutionized natural language processing and computer vision, and are now advancing geospatial analysis and Earth Observation (EO). They…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Pedram Ghamisi , Weikang Yu , Xiaokang Zhang , Aldino Rizaldy , Jian Wang , Chufeng Zhou , Richard Gloaguen , Gustau Camps-Valls

Over the past few years, the landscape of Artificial Intelligence (AI) has been reshaped by the emergence of Foundation Models (FMs). Pre-trained on massive datasets, these models exhibit exceptional performance across diverse downstream…

Machine Learning · Computer Science 2026-02-17 Shenghui Li , Fanghua Ye , Meng Fang , Jiaxu Zhao , Yun-Hin Chan , Edith C. H. Ngai , Thiemo Voigt

Foundation models (FMs) are rapidly reshaping medical imaging, shifting the field from narrowly trained, task-specific networks toward large, general-purpose models that can be adapted across modalities, anatomies, and clinical tasks. In…

Image and Video Processing · Electrical Eng. & Systems 2026-02-19 Chuang Niu , Pengwei Wu , Bruno De Man , Ge Wang

Foundation models have emerged as a powerful approach for processing electronic health records (EHRs), offering flexibility to handle diverse medical data modalities. In this study, we present a comprehensive benchmark that evaluates the…

Machine Learning · Computer Science 2025-07-22 Kunyu Yu , Rui Yang , Jingchi Liao , Siqi Li , Huitao Li , Irene Li , Yifan Peng , Rishikesan Kamaleswaran , Nan Liu

Due to the increase in computational resources and accessibility of data, an increase in large, deep learning models trained on copious amounts of multi-modal data using self-supervised or semi-supervised learning have emerged. These…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Madeline Chantry Schiappa , Shehreen Azad , Sachidanand VS , Yunhao Ge , Ondrej Miksik , Yogesh S. Rawat , Vibhav Vineet

Recent Tabular Foundation Models (TFMs) have demonstrated state-of-the-art predictive performance, often surpassing Gradient-Boosted Decision Trees (GBDTs). However, the trustworthiness of these models, particularly their uncertainty…

Machine Learning · Computer Science 2026-05-28 José Lucas De Melo Costa , Fabrice Popineau , Arpad Rimmel , Bich-Liên Doan

Deep model fusion is an emerging technique that unifies the predictions or parameters of several deep neural networks into a single better-performing model in a cost-effective and data-efficient manner. Although a variety of deep model…

Machine Learning · Computer Science 2025-12-05 Anke Tang , Li Shen , Yong Luo , Enneng Yang , Han Hu , Lefei Zhang , Bo Du , Dacheng Tao

Preference learning is a central component for aligning current LLMs, but this process can be vulnerable to data poisoning attacks. To address this concern, we introduce PoisonBench, a benchmark for evaluating large language models'…

Cryptography and Security · Computer Science 2025-06-09 Tingchen Fu , Mrinank Sharma , Philip Torr , Shay B. Cohen , David Krueger , Fazl Barez

Vision foundation models (FMs) are accelerating the development of digital pathology algorithms and transforming biomedical research. These models learn, in a self-supervised manner, to represent histological features in highly…

Foundation models leverage large-scale pretraining to capture extensive knowledge, demonstrating generalization in a wide range of language tasks. By comparison, vision foundation models (VFMs) often exhibit uneven improvements across…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Shiqi Huang , Yipei Wang , Natasha Thorley , Alexander Ng , Shaheer Saeed , Mark Emberton , Shonit Punwani , Veeru Kasivisvanathan , Dean Barratt , Daniel Alexander , Yipeng Hu

Most state-of-the-art techniques for medical image segmentation rely on deep-learning models. These models, however, are often trained on narrowly-defined tasks in a supervised fashion, which requires expensive labeled datasets. Recent…

Image and Video Processing · Electrical Eng. & Systems 2023-10-04 Heejong Kim , Victor Ion Butoi , Adrian V. Dalca , Daniel J. A. Margolis , Mert R. Sabuncu

Foundation models, first introduced in 2021, refer to large-scale pretrained models (e.g., large language models (LLMs) and vision-language models (VLMs)) that learn from extensive unlabeled datasets through unsupervised methods, enabling…

Pathological assessment guides lung cancer diagnosis, treatment selection, and prognostic evaluation, yet current CPath approaches rely on task-specific models for isolated objectives. Although pan-cancer foundation models offer…

Breast cancer is the most commonly diagnosed cancer and the leading cause of cancer-related mortality in women globally. Mammography is essential for the early detection and diagnosis of breast lesions. Despite recent progress in foundation…

Surface defect inspection is an important task in industrial inspection. Deep learning-based methods have demonstrated promising performance in this domain. Nevertheless, these methods still suffer from misjudgment when encountering…

Computer Vision and Pattern Recognition · Computer Science 2023-09-25 Xiaoheng Jiang , Shilong Tian , Zhiwen Zhu , Yang Lu , Hao Liu , Li Chen , Shupan Li , Mingliang Xu

The diverse nature of protein prediction tasks has traditionally necessitated specialized models, hindering the development of broadly applicable and computationally efficient Protein Language Models (PLMs). In this work, we introduce…

Protein language models (PLMs) have shown promise in improving the understanding of protein sequences, contributing to advances in areas such as function prediction and protein engineering. However, training these models from scratch…

Machine Learning · Computer Science 2024-12-19 Shivasankaran Vanaja Pandi , Bharath Ramsundar

Predictive modeling often faces challenges due to limited data availability and quality, especially in domains where collected features are weakly correlated with outcomes and where additional feature collection is constrained by ethical or…

Machine Learning · Computer Science 2024-10-08 Bingxuan Li , Pengyi Shi , Amy Ward

Pathology foundation models (PFMs) have emerged as powerful tools for analyzing whole slide images (WSIs). However, adapting these pretrained PFMs for specific clinical tasks presents considerable challenges, primarily due to the…

Computer Vision and Pattern Recognition · Computer Science 2025-06-06 Neeraj Kumar , Swaraj Nanda , Siddharth Singi , Jamal Benhamida , David Kim , Jie-Fu Chen , Amir Momeni-Boroujeni , Gregory M. Goldgof , Gabriele Campanella , Chad Vanderbilt