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Artificial intelligence is undergoing a profound transition from a computational instrument to an autonomous originator of scientific knowledge. This emerging paradigm, the AI scientist, is architected to emulate the complete scientific…

Artificial Intelligence · Computer Science 2026-01-21 Guiyao Tie , Pan Zhou , Lichao Sun

With recent Nobel Prizes recognising AI contributions to science, Large Language Models (LLMs) are transforming scientific research by enhancing productivity and reshaping the scientific method. LLMs are now involved in experimental design,…

In AI-assisted decision-making, humans often passively review AI's suggestion and decide whether to accept or reject it as a whole. In such a paradigm, humans are found to rarely trigger analytical thinking and face difficulties in…

Human-Computer Interaction · Computer Science 2025-03-13 Shuai Ma , Qiaoyi Chen , Xinru Wang , Chengbo Zheng , Zhenhui Peng , Ming Yin , Xiaojuan Ma

The emergence of large language models (LLMs) is propelling automated scientific discovery to the next level, with LLM-based Artificial Intelligence (AI) Scientist systems now taking the lead in scientific research. Several influential…

Artificial Intelligence · Computer Science 2025-08-04 Qiujie Xie , Yixuan Weng , Minjun Zhu , Fuchen Shen , Shulin Huang , Zhen Lin , Jiahui Zhou , Zilan Mao , Zijie Yang , Linyi Yang , Jian Wu , Yue Zhang

The increasing availability of large-scale datasets has fueled rapid progress across many scientific fields, creating unprecedented opportunities for research and discovery while posing significant analytical challenges. Recent advances in…

Artificial Intelligence · Computer Science 2025-12-01 Erzhuo Shao , Yifang Wang , Yifan Qian , Zhenyu Pan , Han Liu , Dashun Wang

The powerful reasoning capabilities of Large Language Models (LLMs) in mathematics and coding, combined with their ability to automate complex tasks through agentic frameworks, present unprecedented opportunities for accelerating scientific…

Artificial Intelligence · Computer Science 2025-05-27 Jiabin Tang , Lianghao Xia , Zhonghang Li , Chao Huang

Recent advances in large language models (LLMs) offer unprecedented opportunities to enhance human-AI collaboration in qualitative research methods, including interviews. While interviews are highly valued for gathering deep, contextualized…

Human-Computer Interaction · Computer Science 2025-04-22 Zhe Liu

The recent large language models (LLMs), e.g., ChatGPT, have been able to generate human-like and fluent responses when provided with specific instructions. While admitting the convenience brought by technological advancement, educators…

Computation and Language · Computer Science 2023-12-27 Zijie Zeng , Lele Sha , Yuheng Li , Kaixun Yang , Dragan Gašević , Guanliang Chen

Scientific discovery is a complex cognitive process that has driven human knowledge and technological progress for centuries. While artificial intelligence (AI) has made significant advances in automating aspects of scientific reasoning,…

Machine Learning · Computer Science 2024-12-24 Chandan K Reddy , Parshin Shojaee

Artificial intelligence (AI) is transforming the practice of science. Machine learning and large language models (LLMs) can generate hypotheses at a scale and speed far exceeding traditional methods, offering the potential to accelerate…

Artificial Intelligence · Computer Science 2025-12-18 Cristina Cornelio , Takuya Ito , Ryan Cory-Wright , Sanjeeb Dash , Lior Horesh

The emergence of Large Language Models presents a remarkable opportunity for humanities and social science research. I argue these technologies instantiate what I have called the algorithmic condition, whereby computational systems…

Computers and Society · Computer Science 2025-12-16 David M. Berry

Large Language Models (LLMs) are catalyzing a paradigm shift in scientific discovery, evolving from task-specific automation tools into increasingly autonomous agents and fundamentally redefining research processes and human-AI…

Computation and Language · Computer Science 2025-09-18 Tianshi Zheng , Zheye Deng , Hong Ting Tsang , Weiqi Wang , Jiaxin Bai , Zihao Wang , Yangqiu Song

Large language models (LLMs) are increasingly used in scientific research and discovery, supporting tasks ranging from literature retrieval and synthesis to hypothesis generation, autonomous experimentation, and research evaluation.…

Digital Libraries · Computer Science 2026-05-13 Haoxuan Zhang , Ruochi Li , Yang Zhang , Ting Xiao , Jiangping Chen , Junhua Ding , Haihua Chen

The emergence of Artificial Intelligence (AI) Scientist represents a paradigm shift in scientific discovery, with large language models (LLMs) taking the lead as the primary executor in the entire scientific workflow from idea generation to…

Artificial Intelligence · Computer Science 2025-06-10 Minjun Zhu , Qiujie Xie , Yixuan Weng , Jian Wu , Zhen Lin , Linyi Yang , Yue Zhang

Metcalfe et al (1) argue that the greatest potential for human-AI partnerships lies in their application to highly complex problem spaces. Herein, we discuss three different forms of hybrid team intelligence and posit that across all three…

Human-Computer Interaction · Computer Science 2025-03-03 Kaleb Mcdowell , Nick Waytowich , Javier Garcia , Stephen Gordon , Bryce Bartlett , Jeremy Gaston

With the rapid development of Large Language Models (LLMs), AI agents have demonstrated increasing proficiency in scientific tasks, ranging from hypothesis generation and experimental design to manuscript writing. Such agent systems are…

The rise of powerful large language models (LLMs) brings about tremendous opportunities for innovation but also looming risks for individuals and society at large. We have reached a pivotal moment for ensuring that LLMs and LLM-infused…

Human-Computer Interaction · Computer Science 2023-08-09 Q. Vera Liao , Jennifer Wortman Vaughan

In this paper, we introduce the AI Search Paradigm, a comprehensive blueprint for next-generation search systems capable of emulating human information processing and decision-making. The paradigm employs a modular architecture of four…

Large Language Models (LLMs) are playing an increasingly important role in physics research by assisting with symbolic manipulation, numerical computation, and scientific reasoning. However, ensuring the reliability, transparency, and…

Artificial Intelligence · Computer Science 2025-08-19 Yinggan Xu , Hana Kimlee , Yijia Xiao , Di Luo

Large-scale Language Models (LLMs) have revolutionized human-AI interaction and achieved significant success in the generation of novel ideas. However, current assessments of idea generation overlook crucial factors such as knowledge…

Artificial Intelligence · Computer Science 2025-05-27 Yansheng Qiu , Haoquan Zhang , Zhaopan Xu , Ming Li , Diping Song , Zheng Wang , Kaipeng Zhang
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