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This work aims efficiently estimating the posterior distribution of kinetic parameters for dynamic positron emission tomography (PET) imaging given a measurement of time of activity curve. Considering the inherent information loss from…

Medical Physics · Physics 2023-10-25 Xiaofeng Liu , Thibault Marin , Tiss Amal , Jonghye Woo , Georges El Fakhri , Jinsong Ouyang

Normative models in neuroimaging learn the brain patterns of healthy population distribution and estimate how disease subjects like Alzheimer's Disease (AD) deviate from the norm. Existing variational autoencoder (VAE)-based normative…

Machine Learning · Computer Science 2026-02-06 Sayantan Kumar , Philip Payne , Aristeidis Sotiras

Medical data sets are usually corrupted by noise and missing data. These missing patterns are commonly assumed to be completely random, but in medical scenarios, the reality is that these patterns occur in bursts due to sensors that are off…

Machine Learning · Computer Science 2021-11-09 Daniel Barrejón , Pablo M. Olmos , Antonio Artés-Rodríguez

The key idea of variational auto-encoders (VAEs) resembles that of traditional auto-encoder models in which spatial information is supposed to be explicitly encoded in the latent space. However, the latent variables in VAEs are vectors,…

Machine Learning · Computer Science 2019-01-23 Zhengyang Wang , Hao Yuan , Shuiwang Ji

Multispectral photoacoustic imaging (PAI) is an emerging imaging modality which enables the recovery of functional tissue parameters such as blood oxygenation. However, the underlying inverse problems are potentially ill-posed, meaning that…

This work proposes a unified self-supervised pre-training framework for transferable multi-modal perception representation learning via masked multi-modal reconstruction in Neural Radiance Field (NeRF), namely NeRF-Supervised Masked…

Computer Vision and Pattern Recognition · Computer Science 2023-12-07 Xiaohao Xu

This paper addresses the challenge of generating synthetic electroencephalogram (EEG) covariance matrices for motor imagery brain-computer interface (MI-BCI) applications. Objective: We aim to develop a generative model capable of producing…

Machine Learning · Computer Science 2026-03-12 Viktorija Poļaka , Ivo Pascal de Jong , Andreea Ioana Sburlea

This paper shows that masked autoencoders (MAE) are scalable self-supervised learners for computer vision. Our MAE approach is simple: we mask random patches of the input image and reconstruct the missing pixels. It is based on two core…

Computer Vision and Pattern Recognition · Computer Science 2021-12-21 Kaiming He , Xinlei Chen , Saining Xie , Yanghao Li , Piotr Dollár , Ross Girshick

Purpose: To develop a self-supervised scan-specific deep learning framework for reconstructing accelerated multiparametric quantitative MRI (qMRI). Methods: We propose REFINE-MORE (REference-Free Implicit NEural representation with MOdel…

Medical Physics · Physics 2025-08-05 Ruimin Feng , Albert Jang , Xingxin He , Fang Liu

Masked autoencoders (MAEs) have displayed significant potential in the classification and semantic segmentation of medical images in the last year. Due to the high similarity of human tissues, even slight changes in medical images may…

Computer Vision and Pattern Recognition · Computer Science 2023-05-11 Jiawei Mao , Shujian Guo , Yuanqi Chang , Xuesong Yin , Binling Nie

The computer vision domain has greatly benefited from an abundance of data across many modalities to improve on various visual tasks. Recently, there has been a lot of focus on self-supervised pre-training methods through Masked…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Pîrvu Mihai-Cristian , Marius Leordeanu

Variational autoencoder (VAE) is a popular method for drug discovery and various architectures and pipelines have been proposed to improve its performance. However, VAE approaches are known to suffer from poor manifold recovery when the…

Machine Learning · Computer Science 2023-09-12 Chenghui Zhou , Barnabas Poczos

Masked autoencoders (MAEs) are increasingly applied to electronic health records (EHR) for learning general-purpose representations that support diverse clinical tasks. However, existing approaches typically rely on uniform random masking,…

Machine Learning · Computer Science 2025-12-08 Rajna Fani , Rafi Al Attrach , David Restrepo , Yugang Jia , Leo Anthony Celi , Peter Schüffler

Magnetic Resonance Imaging (MRI) offers unparalleled soft-tissue contrast but is fundamentally limited by long acquisition times. While deep learning-based accelerated MRI can dramatically shorten scan times, the reconstruction from…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Paul Fischer , Jan Nikolas Morshuis , Thomas Küstner , Christian Baumgartner

Expert interpretation of anatomical images of the human brain is the central part of neuro-radiology. Several machine learning-based techniques have been proposed to assist in the analysis process. However, the ML models typically need to…

Multiple signal modalities, such as vision and sounds, are naturally present in real-world phenomena. Recently, there has been growing interest in learning generative models, in particular variational autoencoder (VAE), to for multimodal…

Machine Learning · Computer Science 2024-12-31 Peijie Qiu , Wenhui Zhu , Sayantan Kumar , Xiwen Chen , Xiaotong Sun , Jin Yang , Abolfazl Razi , Yalin Wang , Aristeidis Sotiras

Specifying a governing physical model in the presence of missing physics and recovering its parameters are two intertwined and fundamental problems in science. Modern machine learning allows one to circumvent these, via emulators and…

Machine Learning · Computer Science 2020-06-30 Daniel J. Tait , Theodoros Damoulas

In quantitative Magnetic Resonance Imaging, traditional methods suffer from the so-called Partial Volume Effect (PVE) due to spatial resolution limitations. As a consequence of PVE, the parameters of the voxels containing more than one…

Image and Video Processing · Electrical Eng. & Systems 2019-07-30 Roberto Duarte , Audrey Repetti , Pedro A. Gómez , Mike Davies , Yves Wiaux

Magnetic Particle Imaging is an emerging imaging modality through which it is possible to detect tracers containing superparamagnetic nanoparticles. The exposure of the particles to dynamic magnetic fields generates a non-linear response…

Numerical Analysis · Mathematics 2024-06-19 Vladyslav Gapyak , Thomas März , Andreas Weinmann

Due to the prevalence of scale variance in nature images, we propose to use image scale as a self-supervised signal for Masked Image Modeling (MIM). Our method involves selecting random patches from the input image and downsampling them to…

Computer Vision and Pattern Recognition · Computer Science 2023-08-21 Zhiming Wang , Lin Gu , Feng Lu