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We develop a computational framework to quantify uncertainty in shear elastography imaging of anomalies in tissues. We adopt a Bayesian inference formulation. Given the observed data, a forward model and their uncertainties, we find the…

Numerical Analysis · Mathematics 2023-06-07 Ana Carpio , Elena Cebrian , Andrea Gutierrez

Normative modelling is an emerging method for understanding the underlying heterogeneity within brain disorders like Alzheimer Disease (AD) by quantifying how each patient deviates from the expected normative pattern that has been learned…

Image and Video Processing · Electrical Eng. & Systems 2026-02-06 Sayantan Kumar , Philip Payne , Aristeidis Sotiras

Recent advancements in multimodal Variational AutoEncoders (VAEs) have highlighted their potential for modeling complex data from multiple modalities. However, many existing approaches use relatively straightforward aggregating schemes that…

Machine Learning · Computer Science 2025-02-10 Fouad Oubari , Mohamed El Baha , Raphael Meunier , Rodrigue Décatoire , Mathilde Mougeot

In situ scanning transmission electron microscopy enables observation of the domain dynamics in ferroelectric materials as a function of externally applied bias and temperature. The resultant data sets contain a wealth of information on…

The de novo design of drug molecules is recognized as a time-consuming and costly process, and computational approaches have been applied in each stage of the drug discovery pipeline. Variational autoencoder is one of the computer-aided…

Quantum Physics · Physics 2021-12-24 Junde Li , Swaroop Ghosh

A longstanding computational challenge is the accurate simulation of many-body particle systems. Especially for deriving key characteristics of high-impact but complex systems such as battery materials and high entropy alloys (HEA). While…

Quantum Physics · Physics 2025-11-20 Koen Mesman , Yinglu Tang , Matthias Moller , Boyang Chen , Sebastian Feld

Algorithms for Magnetic Resonance (MR) image reconstruction from undersampled measurements exploit prior information to compensate for missing k-space data. Deep learning (DL) provides a powerful framework for extracting such information…

Computer Vision and Pattern Recognition · Computer Science 2018-12-20 Kerem C. Tezcan , Christian F. Baumgartner , Roger Luechinger , Klaas P. Pruessmann , Ender Konukoglu

Deep learning (DL) methods where interpretability is intrinsically considered as part of the model are required to better understand the relationship of clinical and imaging-based attributes with DL outcomes, thus facilitating their use in…

Image and Video Processing · Electrical Eng. & Systems 2022-12-13 Irem Cetin , Maialen Stephens , Oscar Camara , Miguel Angel Gonzalez Ballester

The surrogate loss of variational autoencoders (VAEs) poses various challenges to their training, inducing the imbalance between task fitting and representation inference. To avert this, the existing strategies for VAEs focus on adjusting…

Neural and Evolutionary Computing · Computer Science 2024-04-02 Zhangkai Wu , Longbing Cao , Lei Qi

Microstructure is key to controlling and understanding the properties of metallic materials, but traditional approaches to describing microstructure capture only a small number of features. To enable data-centric approaches to materials…

Quantitative Magnetic Resonance Imaging (qMRI) provides researchers insight into pathological and physiological alterations of living tissue, with the help of which researchers hope to predict (local) therapeutic efficacy early and…

Applications · Statistics 2008-07-30 Xiaoxi Zhang , Timothy D. Johnson , Roderick J. A. Little , Yue Cao

Stochastic processes provide a mathematically elegant way model complex data. In theory, they provide flexible priors over function classes that can encode a wide range of interesting assumptions. In practice, however, efficient inference…

Machine Learning · Computer Science 2022-09-15 Swapnil Mishra , Seth Flaxman , Tresnia Berah , Harrison Zhu , Mikko Pakkanen , Samir Bhatt

We continue studies of the uncertainty quantification problem in emission tomographies such as PET or SPECT when additional multimodal data (e.g., anatomical MRI images) are available. To solve the aforementioned problem we adapt the…

Machine Learning · Statistics 2021-12-03 Fedor Goncharov , Éric Barat , Thomas Dautremer

Masked autoencoders (MAE) have shown great promise in medical image classification. However, the random masking strategy employed by traditional MAEs may overlook critical areas in medical images, where even subtle changes can indicate…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Joao Batista Florindo , Viviane de Moura

The development of deep learning methods for magnetic resonance spectroscopy (MRS) is often hindered by limited availability of large, high-quality training datasets. While physics-based simulations are commonly used to mitigate this…

Multiple modalities often co-occur when describing natural phenomena. Learning a joint representation of these modalities should yield deeper and more useful representations. Previous generative approaches to multi-modal input either do not…

Machine Learning · Computer Science 2018-11-13 Mike Wu , Noah Goodman

Motivation: Despite advances in the computational analysis of high-throughput molecular profiling assays (e.g. transcriptomics), a dichotomy exists between methods that are simple and interpretable, and ones that are complex but with lower…

Machine Learning · Computer Science 2023-06-12 Pedro Henrique da Costa Avelar , Min Wu , Sophia Tsoka

Effective treatment for rectal cancer relies on accurate lymph node metastasis (LNM) staging. However, radiological criteria based on lymph node (LN) size, shape and texture morphology have limited diagnostic accuracy. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2025-07-17 Benjamin Keel , Aaron Quyn , David Jayne , Maryam Mohsin , Samuel D. Relton

Autoencoders have found widespread application in both their original deterministic form and in their variational formulation (VAEs). In scientific applications and in image processing it is often of interest to consider data that are…

Machine Learning · Statistics 2025-09-09 Justin Bunker , Mark Girolami , Hefin Lambley , Andrew M. Stuart , T. J. Sullivan

Self-supervised learning (SSL) has recently emerged as a key strategy for building foundation models in remote sensing, where the scarcity of annotated data limits the applicability of fully supervised approaches. In this work, we introduce…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Vittorio Bernuzzi , Leonardo Rossi , Tomaso Fontanini , Massimo Bertozzi , Andrea Prati
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