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Medical foundation models show promise to learn broadly generalizable features from large, diverse datasets. This could be the base for reliable cross-modality generalization and rapid adaptation to new, task-specific goals, with only a few…

IMPORTANCE: Modern ultrasound systems are universal diagnostic tools capable of imaging the entire body. However, current AI solutions remain fragmented into single-task tools. This critical gap between hardware versatility and software…

Deformable registration is a fundamental task in medical image processing, aiming to achieve precise alignment by establishing nonlinear correspondences between images. Traditional methods offer good adaptability and interpretability but…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Jing Hu , Kaiwei Yu , Hongjiang Xian , Shu Hu , Xin Wang

Frontier artificial intelligence (AI) models, such as OpenAI's GPT-5 and Meta's DINOv3, have advanced rapidly through training on internet-scale public data, yet such systems lack access to private clinical data. Neuroimaging, in…

The clinical adoption of artificial intelligence (AI) in medical imaging requires models that are both diagnostically accurate and interpretable to clinicians. While current multimodal biomedical foundation models prioritize performance,…

Recent advancements in large language models have significantly accelerated their adoption in healthcare applications, including AI-powered medical consultations, diagnostic report assistance, and medical search tools. However, medical…

Over the past decades, computer-aided diagnosis tools for breast cancer have been developed to enhance screening procedures, yet their clinical adoption remains challenged by data variability and inherent biases. Although foundation models…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Elodie Germani , Ilayda Selin Türk , Fatima Zeineddine , Charbel Mourad , Shadi Albarqouni

Foundation models, pre-trained on large image datasets and capable of capturing rich feature representations, have recently shown potential for zero-shot image registration. However, their performance has mostly been tested in the context…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Hanxue Gu , Yaqian Chen , Nicholas Konz , Qihang Li , Maciej A. Mazurowski

Medical image registration is crucial for various clinical and research applications including disease diagnosis or treatment planning which require alignment of images from different modalities, time points, or subjects. Traditional…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Ahsan Raza Siyal , Markus Haltmeier , Ruth Steiger , Malik Galijasevic , Elke Ruth Gizewski , Astrid Ellen Grams

Medical diagnosis is not a single prediction from a fully specified vignette. It is a sequential workup: clinicians decide what evidence to obtain, revise a differential diagnosis, and stop when the diagnosis is sufficiently supported. Most…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Jiazhen Pan , Weixiang Shen , Jun Li , Julian Canisius , Felix Bitzer , Paula Roßmüller , Jiancheng Yang , Virginie Kreutzinger , Daniel Rueckert , Benedikt Wiestler

Developing robust and versatile deep-learning models is essential for enhancing diagnostic accuracy and guiding clinical interventions in medical imaging, but it requires a large amount of annotated data. The advancement of deep learning…

Computer Vision and Pattern Recognition · Computer Science 2025-03-14 Nahid Ul Islam , DongAo Ma , Jiaxuan Pang , Shivasakthi Senthil Velan , Michael Gotway , Jianming Liang

Artificial intelligence (AI) holds significant promise in transforming medical imaging, enhancing diagnostics, and refining treatment strategies. However, the reliance on extensive multicenter datasets for training AI models poses…

Computer Vision and Pattern Recognition · Computer Science 2024-04-01 Fei Kong , Xiyue Wang , Jinxi Xiang , Sen Yang , Xinran Wang , Meng Yue , Jun Zhang , Junhan Zhao , Xiao Han , Yuhan Dong , Biyue Zhu , Fang Wang , Yueping Liu

Skeletonization is a popular shape analysis technique that models an object's interior as opposed to just its boundary. Fitting template-based skeletal models is a time-consuming process requiring much manual parameter tuning. Recently,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-10 Nicolás Gaggion , Enzo Ferrante , Beatriz Paniagua , Jared Vicory

While emerging 3D medical foundation models are envisioned as versatile tools with offer general-purpose capabilities, their validation remains largely confined to regional and structural imaging, leaving a significant modality discrepancy…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Yichi Zhang , Feiyang Xiao , Le Xue , Wenbo Zhang , Gang Feng , Chenguang Zheng , Yuan Qi , Yuan Cheng , Zixin Hu

Tissue detection is a crucial first step in most digital pathology applications. Details of the segmentation algorithm are rarely reported, and there is a lack of studies investigating the downstream effects of a poor segmentation…

Multiple sclerosis is a chronic autoimmune disease that affects the central nervous system. Understanding multiple sclerosis progression and identifying the implicated brain structures is crucial for personalized treatment decisions.…

Artificial intelligence (AI)-enabled diagnostics in maxillofacial pathology require structured, high-quality multimodal datasets. However, existing resources provide limited ameloblastoma coverage and lack the format consistency needed for…

Artificial Intelligence · Computer Science 2026-02-06 Ajo Babu George , Anna Mariam John , Athul Anoop , Balu Bhasuran

Foundation models for computational pathology are expected to facilitate the development of high-performing, generalisable deep learning systems. However, in addition to biologically relevant features, current foundation models also capture…

In this study, we aim to initiate the development of Radiology Foundation Model, termed as RadFM. We consider the construction of foundational models from three perspectives, namely, dataset construction, model design, and thorough…

Computer Vision and Pattern Recognition · Computer Science 2023-11-17 Chaoyi Wu , Xiaoman Zhang , Ya Zhang , Yanfeng Wang , Weidi Xie

Aortic stenosis (AS) is the most common valvular heart disease in developed countries. High-fidelity preclinical models can improve AS management by enabling therapeutic innovation, early diagnosis, and tailored treatment planning. However,…

Computational Engineering, Finance, and Science · Computer Science 2024-07-02 Caglar Ozturk , Daniel H. Pak , Luca Rosalia , Debkalpa Goswami , Mary E. Robakowski , Raymond McKay , Christopher T. Nguyen , James S. Duncan , Ellen T. Roche