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Large language model (LLM) agents have emerged as powerful tools for complex tasks, yet their ability to adapt to individual users remains fundamentally limited. We argue this limitation stems from a critical architectural conflation:…

Artificial Intelligence · Computer Science 2026-02-17 Deepak Babu Piskala

The vast majority of materials science knowledge exists in unstructured natural language, yet structured data is crucial for innovative and systematic materials design. Traditionally, the field has relied on manual curation and partial…

The history of science is punctuated by serendipitous discoveries, where unexpected observations, rather than targeted hypotheses, opened new fields of inquiry. While modern autonomous laboratories excel at accelerating hypothesis testing,…

Artificial Intelligence · Computer Science 2025-08-12 Lance Yao , Suman Samantray , Ayana Ghosh , Kevin Roccapriore , Libor Kovarik , Sarah Allec , Maxim Ziatdinov

Language-conditioned robotic skills make it possible to apply the high-level reasoning of Large Language Models (LLMs) to low-level robotic control. A remaining challenge is to acquire a diverse set of fundamental skills. Existing…

Robotics · Computer Science 2024-08-19 Xufeng Zhao , Cornelius Weber , Stefan Wermter

Large language model (LLM) agents increasingly rely on reusable skills: capability packages that combine instructions, control flow, constraints, and tool calls. In current agent systems, however, skills are still represented by text-heavy…

Computation and Language · Computer Science 2026-05-05 Qiliang Liang , Hansi Wang , Zhong Liang , Yang Liu

Discovering new materials can have significant scientific and technological implications but remains a challenging problem today due to the enormity of the chemical space. Recent advances in machine learning have enabled data-driven methods…

Materials Science · Physics 2024-06-21 Shuyi Jia , Chao Zhang , Victor Fung

Solving mechanics problems using numerical methods requires comprehensive intelligent capability of retrieving relevant knowledge and theory, constructing and executing codes, analyzing the results, a task that has thus far mainly been…

Artificial Intelligence · Computer Science 2023-11-15 Bo Ni , Markus J. Buehler

Recent significant advances in integrating multiple Large Language Model (LLM) systems have enabled Agentic Frameworks capable of performing complex tasks autonomously, including novel scientific research. We develop and demonstrate such a…

Artificial Intelligence · Computer Science 2025-07-16 Darui Lu , Jordan M. Malof , Willie J. Padilla

Transformer neural networks show promising capabilities, in particular for uses in materials analysis, design and manufacturing, including their capacity to work effectively with both human language, symbols, code, and numerical data. Here…

Computation and Language · Computer Science 2023-11-01 Markus J. Buehler

Computing has long served as a cornerstone of scientific discovery. Recently, a paradigm shift has emerged with the rise of large language models (LLMs), introducing autonomous systems, referred to as agents, that accelerate discovery…

Autonomous agents have long been a prominent research focus in both academic and industry communities. Previous research in this field often focuses on training agents with limited knowledge within isolated environments, which diverges…

Artificial Intelligence · Computer Science 2025-03-04 Lei Wang , Chen Ma , Xueyang Feng , Zeyu Zhang , Hao Yang , Jingsen Zhang , Zhiyuan Chen , Jiakai Tang , Xu Chen , Yankai Lin , Wayne Xin Zhao , Zhewei Wei , Ji-Rong Wen

Physics-based simulation underpins engineering analysis but remains difficult to deploy in practice due to complex setup, parameterization, and interpretation. While Large Language Model-based agentic systems have shown promise in…

Computational Engineering, Finance, and Science · Computer Science 2026-05-12 Danrong Zhang , Ruijia Wang , Chenying Liu , Yumeng Zhao

Imagine decision-makers uploading data and, within minutes, receiving clear, actionable insights delivered straight to their fingertips. That is the promise of the AI Data Scientist, an autonomous Agent powered by large language models…

Artificial Intelligence · Computer Science 2025-08-26 Farkhad Akimov , Munachiso Samuel Nwadike , Zangir Iklassov , Martin Takáč

Designing autonomous driving systems requires efficient exploration of large hardware/software configuration spaces under diverse environmental conditions, e.g., with varying traffic, weather, and road layouts. Traditional design space…

Robotics · Computer Science 2025-12-10 Po-An Shih , Shao-Hua Wang , Yung-Che Li , Chia-Heng Tu , Chih-Han Chang

Large language model (LLM)-based agents are increasingly used to perform complex, multi-step workflows in regulated settings such as compliance and due diligence. However, many agentic architectures rely primarily on prompt engineering of a…

Artificial Intelligence · Computer Science 2026-02-03 Ananya Joshi , Michael Rudow

Molecular property prediction and generative design via deep learning models has been the subject of intense research given its potential to accelerate development of new, high-performance materials. More recently, these workflows have been…

Artificial Intelligence · Computer Science 2024-12-16 Nathaniel H. Park , Tiffany J. Callahan , James L. Hedrick , Tim Erdmann , Sara Capponi

Automated machine learning (AutoML) accelerates AI development by automating tasks in the development pipeline, such as optimal model search and hyperparameter tuning. Existing AutoML systems often require technical expertise to set up…

Machine Learning · Computer Science 2025-06-09 Patara Trirat , Wonyong Jeong , Sung Ju Hwang

In recent years, multi-agent frameworks powered by large language models (LLMs) have advanced rapidly. Despite this progress, there is still a notable absence of benchmark datasets specifically tailored to evaluate their performance. To…

Computation and Language · Computer Science 2025-04-28 Lei Shen , Xiaoyu Shen

Autonomous agents powered by large language models (LLMs) have shown impressive capabilities in tool manipulation for complex task-solving. However, existing paradigms such as ReAct rely on sequential reasoning and execution, failing to…

Artificial Intelligence · Computer Science 2025-10-30 Jiaqi Wu , Qinlao Zhao , Zefeng Chen , Kai Qin , Yifei Zhao , Xueqian Wang , Yuhang Yao

This paper introduces Agent-Based Auto Research, a structured multi-agent framework designed to automate, coordinate, and optimize the full lifecycle of scientific research. Leveraging the capabilities of large language models (LLMs) and…

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