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Dynamic computed tomography perfusion (CTP) imaging is a promising approach for acute ischemic stroke diagnosis and evaluation. Hemodynamic parametric maps of cerebral parenchyma are calculated from repeated CT scans of the first pass of…

Medical Physics · Physics 2020-05-21 Dufan Wu , Hui Ren , Quanzheng Li

While Computed Tomography (CT) reconstruction from X-ray sinograms is necessary for clinical diagnosis, iodine radiation in the imaging process induces irreversible injury, thereby driving researchers to study sparse-view CT reconstruction,…

Image and Video Processing · Electrical Eng. & Systems 2021-11-29 Ce Wang , Kun Shang , Haimiao Zhang , Qian Li , Yuan Hui , S. Kevin Zhou

We are exploring low-dose proton radiography and computed tomography (pCT) as techniques to improve the accuracy of proton treatment planning and to provide artifact-free images for verification and adaptive therapy at the time of…

Photon counting CT (PCCT) has been a research focus in the last two decades. Recent studies and advancements have demonstrated that systems using semiconductor-based photon counting detectors (PCDs) have the potential to provide better…

This study aims to improve photon counting CT (PCCT) image resolution using denoising diffusion probabilistic models (DDPM). Although DDPMs have shown superior performance when applied to various computer vision tasks, their effectiveness…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Chuang Niu , Christopher Wiedeman , Mengzhou Li , Jonathan S Maltz , Ge Wang

Sparse views X-ray computed tomography has emerged as a contemporary technique to mitigate radiation dose. Because of the reduced number of projection views, traditional reconstruction methods can lead to severe artifacts. Recently,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Liutao Yang , Jiahao Huang , Guang Yang , Daoqiang Zhang

With the development of computed tomography (CT) imaging technology, it is possible to acquire multi-energy data by spectral CT. Being different from conventional CT, the X-ray energy spectrum of spectral CT is cutting into several narrow…

Medical Physics · Physics 2023-01-25 Yuanwei He , Li Zeng , Qiong Xu , Zhe Wang , Haijun Yu , Zhaoqiang Shen , Zhaojun Yang , Rifeng Zhou

Computed tomography (CT) is widely used in scientific imaging systems such as synchrotron and laboratory-based nano-CT, but acquiring full-view sinograms requires high radiation dose and long scan times. Sparse-view CT reduces this burden…

Image and Video Processing · Electrical Eng. & Systems 2026-02-10 Jiaze E , Srutarshi Banerjee , Tekin Bicer , Guannan Wang , Yanfu Zhang , Bin Ren

Computed tomography and magnetic resonance imaging are two widely used clinical imaging modalities for non-invasive diagnosis. However, both of these modalities come with certain problems. CT uses harmful ionising radiation, and MRI suffers…

Image and Video Processing · Electrical Eng. & Systems 2023-03-03 Philipp Ernst , Soumick Chatterjee , Georg Rose , Oliver Speck , Andreas Nürnberger

We summarize recent results and ongoing activities in mathematical algorithms and computer science methods related to proton computed tomography (pCT) and intensity-modulated particle therapy (IMPT) treatment planning. Proton therapy…

Medical Physics · Physics 2021-08-24 Yair Censor , Keith E. Schubert , Reinhard W. Schulte

Dual-energy computed tomography (DECT) has shown great potential and promising applications in advanced imaging fields for its capabilities of material decomposition. However, image reconstructions and decompositions under sparse views…

Medical Physics · Physics 2016-08-01 Lei Li , Ailong Cai , Linyuan Wang , Bin Yan , Hanming Zhang , Zhizhong Zheng , Wenkun Zhang , Wanli Lu , Guoen Hu

For a century, clinical X-ray imaging has visualised only the attenuation properties of tissue, which fundamentally limits the contrast, particularly in soft tissues like the breast. Imaging based on refraction can overcome this limitation,…

Computed Tomography (CT) reconstruction is a fundamental component to a wide variety of applications ranging from security, to healthcare. The classical techniques require measuring projections, called sinograms, from a full 180$^\circ$…

Computer Vision and Pattern Recognition · Computer Science 2018-07-12 Rushil Anirudh , Hyojin Kim , Jayaraman J. Thiagarajan , K. Aditya Mohan , Kyle Champley , Timo Bremer

We introduce Intrinsic Image Fusion, a method that reconstructs high-quality physically based materials from multi-view images. Material reconstruction is highly underconstrained and typically relies on analysis-by-synthesis, which requires…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Peter Kocsis , Lukas Höllein , Matthias Nießner

Purpose: This study proposes a systematic method for determining the optimal x-ray tube settings/energy windows and fluence for minimal noise and maximum CNR in material density images obtained from DECT scans by fixing the subject size and…

Medical Physics · Physics 2023-08-02 Fatma Terzioglu , Emil Y. Sidky , Jp Phillips , Ingrid Reiser , Guillaume Bal , Xiaochuan Pan

Carbon ion beam radiotherapy enables a very localised dose deposition. However, already small changes in the patient geometry or positioning errors can significantly distort the dose distribution. A live monitoring system of the beam…

Ultra low radiation dose in X-ray Computed Tomography (CT) is an important clinical objective in order to minimize the risk of carcinogenesis. Compressed Sensing (CS) enables significant reductions in radiation dose to be achieved by…

Limited-angle computed tomography (LACT) reconstruction is an inverse problem with severe ill-posedness arising from missing projection angles, and it is difficult to restore high-precision images without sufficient prior knowledge. In…

Image and Video Processing · Electrical Eng. & Systems 2026-03-06 Hinako Isogai , Naruki Murahashi , Mitsuhiro Nakamura , Megumi Nakao

As the medical usage of computed tomography (CT) continues to grow, the radiation dose should remain at a low level to reduce the health risks. Therefore, there is an increasing need for algorithms that can reconstruct high-quality images…

Image and Video Processing · Electrical Eng. & Systems 2021-03-10 Davood Karimi , Rabab K. Ward

X-ray computed tomography (CT) is widely used for medical diagnosis and treatment planning; however, concerns about ionizing radiation exposure drive efforts to optimize image quality at lower doses. This study introduces Poisson Flow…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Dennis Hein , Grant Stevens , Adam Wang , Ge Wang