Related papers: hSNMF: Hybrid Spatially Regularized NMF for Image-…
Nonnegative matrix factorization (NMF) has found many applications including topic modeling and document analysis. Hierarchical NMF (HNMF) variants are able to learn topics at various levels of granularity and illustrate their hierarchical…
We propose a novel methodology for forecasting spatio-temporal data using supervised semi-nonnegative matrix factorization (SSNMF) with frequency regularization. Matrix factorization is employed to decompose spatio-temporal data into…
Spectral computed tomography (CT) reconstructs material-dependent attenuation images with the projections of multiple narrow energy windows, it is meaningful for material identification and decomposition. Unfortunately, the multi-energy…
The performance of single image super-resolution has achieved significant improvement by utilizing deep convolutional neural networks (CNNs). The features in deep CNN contain different types of information which make different contributions…
Advances in spatial transcriptomics (ST) technologies enable systematic molecular characterization of tumor microenvironment, tumor gradients and gene regulatory networks. Cancer progression is known to vary along pathological gradients,…
Spatial transcriptomics (ST) enables gene expression mapping within anatomical context but remains costly and low-throughput. Hematoxylin and eosin (H\&E) staining offers rich morphology yet lacks molecular resolution. We present…
Spatial Transcriptomics (ST) enables the measurement of gene expression while preserving spatial information, offering critical insights into tissue architecture and disease pathology. Recent developments have explored the use of…
Hyperspectral image (HSI) denoising is an essential procedure for HSI applications. Unfortunately, the existing Transformer-based methods mainly focus on non-local modeling, neglecting the importance of locality in image denoising.…
Symmetric nonnegative matrix factorization (SNMF) has demonstrated to be a powerful method for data clustering. However, SNMF is mathematically formulated as a non-convex optimization problem, making it sensitive to the initialization of…
Matrix factorization techniques, especially Nonnegative Matrix Factorization (NMF), have been widely used for dimensionality reduction and interpretable data representation. However, existing NMF-based methods are inherently single-scale…
Spatial transcriptomics is an emerging field that enables the identification of functional regions based on the spatial distribution of gene expression. Integrating this functional information present in transcriptomic data with structural…
Non-negative matrix factorization (NMF) and non-negative tensor factorization (NTF) decompose non-negative high-dimensional data into non-negative low-rank components. NMF and NTF methods are popular for their intrinsic interpretability and…
Hyperspectral unmixing (HU) is a critical yet challenging task in remote sensing. However, existing nonnegative matrix factorization (NMF) methods with graph learning mostly focus on first-order or second-order nearest neighbor…
Traditional nonnegative matrix factorization (NMF) learns a new feature representation on the whole data space, which means treating all features equally. However, a subspace is often sufficient for accurate representation in practical…
Efficient extraction of spectral sequences and geospatial information has always been a hot topic in hyperspectral image classification. In terms of spectral sequence feature capture, RNN and Transformer have become mainstream…
Spatial transcriptomics (ST) enables simultaneous mapping of tissue morphology and spatially resolved gene expression, offering unique opportunities to study tumor microenvironment heterogeneity. Here, we introduce a computational framework…
Synthesizing medical images while preserving their structural information is crucial in medical research. In such scenarios, the preservation of anatomical content becomes especially important. Although recent advances have been made by…
Extracting genetic information from a full range of sequencing data is important for understanding diseases. We propose a novel method to effectively explore the landscape of genetic mutations and aggregate them to predict cancer type. We…
We propose a new variant of nonnegative matrix factorization (NMF), combining separability and sparsity assumptions. Separability requires that the columns of the first NMF factor are equal to columns of the input matrix, while sparsity…
Multi-Modal Image Fusion (MMIF) aims to integrate complementary image information from different modalities to produce informative images. Previous deep learning-based MMIF methods generally adopt Convolutional Neural Networks (CNNs) or…