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Understanding how deep learning models predict oncology patient risk can provide critical insights into disease progression, support clinical decision-making, and pave the way for trustworthy and data-driven precision medicine. Building on…

Computer Vision and Pattern Recognition · Computer Science 2024-11-13 Marvin Sextro , Gabriel Dernbach , Kai Standvoss , Simon Schallenberg , Frederick Klauschen , Klaus-Robert Müller , Maximilian Alber , Lukas Ruff

Deep learning methods, in particular convolutional neural networks, have emerged as a powerful tool in medical image computing tasks. While these complex models provide excellent performance, their black-box nature may hinder real-world…

Image and Video Processing · Electrical Eng. & Systems 2022-10-18 Yuzhe Lu , Adam Perer

Recent developments in generative artificial intelligence (AI) rely on machine learning techniques such as deep learning and generative modeling to achieve state-of-the-art performance across wide-ranging domains. These methods' surprising…

Machine Learning · Statistics 2026-01-27 Gemma E. Moran , Bryon Aragam

Known for its high morbidity and mortality rates, lung cancer poses a significant threat to human health and well-being. However, the same population is also at high risk for other deadly diseases, such as cardiovascular disease. Since…

Computer Vision and Pattern Recognition · Computer Science 2018-10-22 Pingkun Yan , Hengtao Guo , Ge Wang , Ruben De Man , Mannudeep K. Kalra

Respiratory diseases remain major global health challenges, and traditional auscultation is often limited by subjectivity, environmental noise, and inter-clinician variability. This study presents an explainable multimodal deep learning…

Sound · Computer Science 2025-12-02 S M Asiful Islam Saky , Md Rashidul Islam , Md Saiful Arefin , Shahaba Alam

Interpretability of deep learning is widely used to evaluate the reliability of medical imaging models and reduce the risks of inaccurate patient recommendations. For models exceeding human performance, e.g. predicting RNA structure from…

Quantitative Methods · Quantitative Biology 2022-08-31 Mara Graziani , Niccolò Marini , Nicolas Deutschmann , Nikita Janakarajan , Henning Müller , María Rodríguez Martínez

Skin cancer is one of the most prevalent and potentially life-threatening diseases worldwide, necessitating early and accurate diagnosis to improve patient outcomes. Conventional diagnostic methods, reliant on clinical expertise and…

Computer Vision and Pattern Recognition · Computer Science 2025-01-28 Mirza Ahsan Ullah , Tehseen Zia

Melanoma represents a critical health risk due to its aggressive progression and high mortality, underscoring the need for early, interpretable diagnostic tools. While deep learning has advanced in skin lesion classification, most existing…

Computer Vision and Pattern Recognition · Computer Science 2025-07-28 Ciro Listone , Aniello Murano

Invasive ductal carcinoma is a prevalent, potentially deadly disease associated with a high rate of morbidity and mortality. Its malignancy is the second leading cause of death from cancer in women. The mammogram is an extremely useful…

Computer Vision and Pattern Recognition · Computer Science 2021-11-09 Rushabh Patel

In supervised learning for medical image analysis, sample selection methodologies are fundamental to attain optimum system performance promptly and with minimal expert interactions (e.g. label querying in an active learning setup). In this…

Computer Vision and Pattern Recognition · Computer Science 2021-04-14 Dwarikanath Mahapatra

Lung cancer is the leading cause of cancer death worldwide. The critical reason for the deaths is delayed diagnosis and poor prognosis. With the accelerated development of deep learning techniques, it has been successfully applied…

Image and Video Processing · Electrical Eng. & Systems 2021-06-15 Yujiao Wu , Jie Ma , Xiaoshui Huang , Sai Ho Ling , Steven Weidong Su

Lung cancer (LC) is a leading cause of cancer-related mortality in the United States. Accurate prediction of LC mortality rates is crucial for guiding targeted interventions and addressing health disparities. Although traditional…

Machine Learning · Computer Science 2025-12-23 Soheil Hashtarkhani , Brianna M. White , Benyamin Hoseini , David L. Schwartz , Arash Shaban-Nejad

Flexible laryngoscopy is commonly performed by otolaryngologists to detect laryngeal diseases and to recognize potentially malignant lesions. Recently, researchers have introduced machine learning techniques to facilitate automated…

Computer Vision and Pattern Recognition · Computer Science 2023-05-29 Tianxiao Zhang , Andrés M. Bur , Shannon Kraft , Hannah Kavookjian , Bryan Renslo , Xiangyu Chen , Bo Luo , Guanghui Wang

We introduce CausaLab, a scalable environment for evaluating interactive causal discovery by LLM agents. Unlike prior evaluations, CausaLab evaluates both whether an agent can solve a problem using causal evidence and whether its answer is…

Artificial Intelligence · Computer Science 2026-05-29 Junlin Yang , Dylan Zhang , Xiangchen Song , Qirun Dai , Xiao Liu , Yuen Chen , Aniket Vashishtha , Jing Shi , Chenhao Tan , Hao Peng

Accurate lung cancer risk prediction remains challenging due to substantial variability across patient populations and clinical settings -- no single model performs best for all cohorts. To address this, we propose a personalized lung…

Machine Learning · Computer Science 2025-08-27 Chongyu Qu , Allen J. Luna , Thomas Z. Li , Junchao Zhu , Junlin Guo , Juming Xiong , Kim L. Sandler , Bennett A. Landman , Yuankai Huo

Deep learning models achieve high predictive performance but lack intrinsic interpretability, hindering our understanding of the learned prediction behavior. Existing local explainability methods focus on associations, neglecting the causal…

Machine Learning · Computer Science 2025-09-18 Niklas Penzel , Joachim Denzler

Lung cancer is highly lethal, emphasizing the critical need for early detection. However, identifying lung nodules poses significant challenges for radiologists, who rely heavily on their expertise for accurate diagnosis. To address this…

Image and Video Processing · Electrical Eng. & Systems 2023-10-17 Hossein Jafari , Karim Faez , Hamidreza Amindavar

Cancer is a fatal disease caused by a combination of genetic diseases and a variety of biochemical abnormalities. Lung and colon cancer have emerged as two of the leading causes of death and disability in humans. The histopathological…

Image and Video Processing · Electrical Eng. & Systems 2022-06-06 Md. Alamin Talukder , Md. Manowarul Islam , Md Ashraf Uddin , Arnisha Akhter , Khondokar Fida Hasan , Mohammad Ali Moni

Lung cancer is a major cause of cancer-related deaths, and early diagnosis and treatment are crucial for improving patients' survival outcomes. In this paper, we propose to employ convolutional neural networks to model the non-linear…

Image and Video Processing · Electrical Eng. & Systems 2024-08-20 Xiawei Wang , James Sharpnack , Thomas C. M. Lee

Deep learning shows promise for medical image analysis but lacks interpretability, hindering adoption in healthcare. Attribution techniques that explain model reasoning may increase trust in deep learning among clinical stakeholders. This…

Machine Learning · Computer Science 2023-08-08 Yusuf Brima , Marcellin Atemkeng