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Large-scale neuroscience is generating rich datasets across animals, brain areas and behavioral contexts, yet our modeling efforts remains fragmented across isolated experiments. We argue that understanding behavior requires integrative…

Foundation models (FMs) such as large language models have revolutionized the field of AI by showing remarkable performance in various tasks. However, they exhibit numerous limitations that prevent their broader adoption in many real-world…

Artificial Intelligence · Computer Science 2024-02-05 Debarun Bhattacharjya , Junkyu Lee , Don Joven Agravante , Balaji Ganesan , Radu Marinescu

Deep neural networks have emerged as the workhorse for a large section of robotics and control applications, especially as models for dynamical systems. Such data-driven models are in turn used for designing and verifying autonomous…

Machine Learning · Computer Science 2023-11-08 Kaustubh Sridhar , Souradeep Dutta , James Weimer , Insup Lee

Can artificial intelligence unlock the secrets of the human brain? How do the inner mechanisms of deep learning models relate to our neural circuits? Is it possible to enhance AI by tapping into the power of brain recordings? These…

Neurons and Cognition · Quantitative Biology 2024-12-31 Subba Reddy Oota , Zijiao Chen , Manish Gupta , Raju S. Bapi , Gael Jobard , Frederic Alexandre , Xavier Hinaut

With the wide adoption of functional magnetic resonance imaging (fMRI) by cognitive neuroscience researchers, large volumes of brain imaging data have been accumulated in recent years. Aggregating these data to derive scientific insights…

Applications · Statistics 2020-06-01 Ming Bo Cai , Michael Shvartsman , Anqi Wu , Hejia Zhang , Xia Zhu

Mental health disorders are rising worldwide. However, the availability of trained clinicians has not scaled proportionally, leaving many people without adequate or timely support. To bridge this gap, recent studies have shown the promise…

Computation and Language · Computer Science 2025-08-19 Aishik Mandal , Prottay Kumar Adhikary , Hiba Arnaout , Iryna Gurevych , Tanmoy Chakraborty

This paper surveys foundation models for AI-enabled biological design, focusing on recent developments in applying large-scale, self-supervised models to tasks such as protein engineering, small molecule design, and genomic sequence design.…

Artificial Intelligence · Computer Science 2025-05-20 Asher Moldwin , Amarda Shehu

Large pre-trained models, or foundation models, have shown impressive performance when adapted to a variety of downstream tasks, often out-performing specialized models. Hypernetworks, neural networks that generate some or all of the…

Machine Learning · Computer Science 2025-03-04 Jeffrey Gu , Serena Yeung-Levy

Foundation models for computational pathology are expected to facilitate the development of high-performing, generalisable deep learning systems. However, in addition to biologically relevant features, current foundation models also capture…

Recent progress in self-supervision shows that pre-training large neural networks on vast amounts of unsupervised data can lead to impressive increases in generalisation for downstream tasks. Such models, recently coined as foundation…

Many Artificial Intelligence systems depend on the agent's updating its beliefs about the world on the basis of experience. Experiments constitute one type of experience, so scientific methodology offers a natural environment for examining…

Artificial Intelligence · Computer Science 2013-04-08 Harold P. Lehmann

Over the last years, topic modeling has emerged as a powerful technique for organizing and summarizing big collections of documents or searching for particular patterns in them. However, privacy concerns may arise when cross-analyzing data…

Machine Learning · Computer Science 2023-06-13 Lorena Calvo-Bartolomé , Jerónimo Arenas-García

Responding to the rapid roll-out and large-scale commercialization of foundation models, large language models, and generative AI, an emerging body of work is shedding light on the myriad impacts these technologies are having across…

The rapid evolution of artificial intelligence (AI) has shifted from static, data-driven models to dynamic systems capable of perceiving and interacting with real-world environments. Despite advancements in pattern recognition and symbolic…

Evaluating foundation models under appropriate adaptation settings is essential for understanding the quality and transferability of the learned representations. Recent EEG foundation models have demonstrated promising transfer capabilities…

Machine Learning · Computer Science 2026-05-28 Aditya Kommineni , Emily Zhou , Kleanthis Avramidis , Tiantian Feng , Shrikanth Narayanan

Foundation models (FMs) are large-scale deep learning models trained on massive datasets, often using self-supervised learning techniques. These models serve as a versatile base for a wide range of downstream tasks, including those in…

Machine Learning · Computer Science 2025-01-17 Wasif Khan , Seowung Leem , Kyle B. See , Joshua K. Wong , Shaoting Zhang , Ruogu Fang

Recent breakthroughs in artificial intelligence (AI) are reshaping the way we construct computational counterparts of the brain, giving rise to a new class of ``surrogate brains''. In contrast to conventional hypothesis-driven biophysical…

Neurons and Cognition · Quantitative Biology 2025-10-14 Yinuo Zhang , Demao Liu , Zhichao Liang , Jiani Cheng , Kexin Lou , Jinqiao Duan , Ting Gao , Bin Hu , Quanying Liu

Artificial intelligence (AI) research today is largely driven by ever-larger neural network models trained on graphics processing units (GPUs). This paradigm has yielded remarkable progress, but it also risks entrenching a hardware lottery…

Artificial Intelligence · Computer Science 2025-11-17 Bipin Rajendran , Osvaldo Simeone , Bashir M. Al-Hashimi

Large-scale brain imaging datasets provide unprecedented opportunities for developing domain foundation models through pretraining. However, unlike natural image datasets in computer vision, these neuroimaging data often exhibit high…

Computer Vision and Pattern Recognition · Computer Science 2025-12-19 Yanteng Zhang , Songheng Li , Zeyu Shen , Qizhen Lan , Lipei Zhang , Yang Liu , Vince Calhoun

Artificial intelligence (AI) governance is the body of standards and practices used to ensure that AI systems are deployed responsibly. Current AI governance approaches consist mainly of manual review and documentation processes. While such…

Computers and Society · Computer Science 2023-02-17 Sean McGregor , Jesse Hostetler
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