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3D Gaussian Splatting (3DGS) has achieved impressive rendering performance in novel view synthesis. However, its efficacy diminishes considerably in sparse image sequences, where inherent data sparsity amplifies geometric uncertainty during…

Computer Vision and Pattern Recognition · Computer Science 2025-03-17 Zhen Tan , Xieyuanli Chen , Jinpu Zhang , Lei Feng , Dewen Hu

Prior parameter distributions provide an elegant way to represent prior expert and world knowledge for informed learning. Previous work has shown that using such informative priors to regularize probabilistic deep learning (DL) models…

Machine Learning · Computer Science 2024-11-06 Christian Schlauch , Christian Wirth , Nadja Klein

Diabetic Retinopathy (DR) is one of the microvascular complications of Diabetes Mellitus, which remains as one of the leading causes of blindness worldwide. Computational models based on Convolutional Neural Networks represent the state of…

Computer Vision and Pattern Recognition · Computer Science 2020-07-31 Santiago Toledo-Cortés , Melissa De La Pava , Oscar Perdómo , Fabio A. González

Deep Learning models are easily disturbed by variations in the input images that were not seen during training, resulting in unpredictable behaviours. Such Out-of-Distribution (OOD) images represent a significant challenge in the context of…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Benjamin Lambert , Florence Forbes , Senan Doyle , Alan Tucholka , Michel Dojat

Normative modeling has recently been proposed as an alternative for the case-control approach in modeling heterogeneity within clinical cohorts. Normative modeling is based on single-output Gaussian process regression that provides coherent…

Machine Learning · Statistics 2018-06-07 Seyed Mostafa Kia , Andre Marquand

In image segmentation, there is often more than one plausible solution for a given input. In medical imaging, for example, experts will often disagree about the exact location of object boundaries. Estimating this inherent uncertainty and…

Computer Vision and Pattern Recognition · Computer Science 2020-12-23 Miguel Monteiro , Loïc Le Folgoc , Daniel Coelho de Castro , Nick Pawlowski , Bernardo Marques , Konstantinos Kamnitsas , Mark van der Wilk , Ben Glocker

Deep neural networks (DNNs) achieve promising performance in visual recognition under the independent and identically distributed (IID) hypothesis. In contrast, the IID hypothesis is not universally guaranteed in numerous real-world…

Image and Video Processing · Electrical Eng. & Systems 2023-06-27 Shuai Wang , Zipei Yan , Daoan Zhang , Zhongsen Li , Sirui Wu , Wenxuan Chen , Rui Li

Mammographic screening is an effective method for detecting breast cancer, facilitating early diagnosis. However, the current need to manually inspect images places a heavy burden on healthcare systems, spurring a desire for automated…

Image and Video Processing · Electrical Eng. & Systems 2025-01-30 Ciaran Bench , Emir Ahmed , Spencer A. Thomas

Deep neural networks are increasingly being used for the analysis of medical images. However, most works neglect the uncertainty in the model's prediction. We propose an uncertainty-aware deep kernel learning model which permits the…

Machine Learning · Computer Science 2021-06-11 Zhiliang Wu , Yinchong Yang , Jindong Gu , Volker Tresp

One major impediment to the wider use of deep learning for clinical decision making is the difficulty of assigning a level of confidence to model predictions. Currently, deep Bayesian neural networks and sparse Gaussian processes are the…

Computer-aided diagnosis systems must make critical decisions from medical images that are often noisy, ambiguous, or conflicting, yet today's models are trained on overly simplistic labels that ignore diagnostic uncertainty. One-hot labels…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Ang Nan Gu , Michael Tsang , Hooman Vaseli , Purang Abolmaesumi , Teresa Tsang

In computational histopathology algorithms now outperform humans on a range of tasks, but to date none are employed for automated diagnoses in the clinic. Before algorithms can be involved in such high-stakes decisions they need to "know…

Computer Vision and Pattern Recognition · Computer Science 2022-10-19 Lea Goetz

Deep neural networks are known to be data-driven and label noise can have a marked impact on model performance. Recent studies have shown great robustness to classic image recognition even under a high noisy rate. In medical applications,…

Computer Vision and Pattern Recognition · Computer Science 2021-03-23 Lie Ju , Xin Wang , Lin Wang , Dwarikanath Mahapatra , Xin Zhao , Mehrtash Harandi , Tom Drummond , Tongliang Liu , Zongyuan Ge

Gaussian processes (GPs) are Bayesian non-parametric models popular in a variety of applications due to their accuracy and native uncertainty quantification (UQ). Tuning GP hyperparameters is critical to ensure the validity of prediction…

Machine Learning · Computer Science 2022-11-03 Killian Wood , Alec M. Dunton , Amanda Muyskens , Benjamin W. Priest

We consider the problem of uncertainty estimation in the context of (non-Bayesian) deep neural classification. In this context, all known methods are based on extracting uncertainty signals from a trained network optimized to solve the…

Machine Learning · Computer Science 2019-04-25 Yonatan Geifman , Guy Uziel , Ran El-Yaniv

Graph Neural Networks have achieved impressive results across diverse network modeling tasks, but accurately estimating uncertainty on graphs remains difficult, especially under distributional shifts. Unlike traditional uncertainty…

Machine Learning · Computer Science 2025-10-15 Fred Xu , Thomas Markovich

Understanding which concepts models can and cannot represent has been fundamental to many tasks: from effective and responsible use of models to detecting out of distribution data. We introduce Gaussian process probes (GPP), a unified and…

Machine Learning · Computer Science 2023-11-07 Zi Wang , Alexander Ku , Jason Baldridge , Thomas L. Griffiths , Been Kim

Medical image segmentation supports clinical workflows by precisely delineating anatomical structures and lesions. However, medical image datasets medical image datasets suffer from acquisition noise and annotation ambiguity, causing…

Artificial Intelligence · Computer Science 2026-04-14 Ruiyang Li , Fang Liu , Licheng Jiao , Xinglin Xie , Jiayao Hao , Shuo Li , Xu Liu , Jingyi Yang , Lingling Li , Puhua Chen , Wenping Ma

Reliable uncertainty estimates are crucial in modern machine learning. Deep Gaussian Processes (DGPs) and Deep Sigma Point Processes (DSPPs) extend GPs hierarchically, offering promising methods for uncertainty quantification grounded in…

Machine Learning · Statistics 2025-04-25 Matthijs van der Lende , Jeremias Lino Ferrao , Niclas Müller-Hof

Image-to-image translation plays a vital role in tackling various medical imaging tasks such as attenuation correction, motion correction, undersampled reconstruction, and denoising. Generative adversarial networks have been shown to…

Computer Vision and Pattern Recognition · Computer Science 2021-07-05 Uddeshya Upadhyay , Yanbei Chen , Tobias Hepp , Sergios Gatidis , Zeynep Akata