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Excel is a pervasive yet often complex tool, particularly for novice users, where runtime errors arising from logical mistakes or misinterpretations of functions pose a significant challenge. While large language models (LLMs) offer…

Microstructure plays a critical role in determining the macroscopic properties of materials, with applications spanning alloy design, MEMS devices, and tissue engineering, among many others. Computational frameworks have been developed to…

Computational Engineering, Finance, and Science · Computer Science 2024-09-24 Nikita Kartashov , Nikolaos N. Vlassis

Public Narratives (PNs) are key tools for leadership development and civic mobilization, yet their systematic analysis remains challenging due to their subjective interpretation and the high cost of expert annotation. In this work, we…

Computation and Language · Computer Science 2025-11-18 Elinor Poole-Dayan , Daniel T Kessler , Hannah Chiou , Margaret Hughes , Emily S Lin , Marshall Ganz , Deb Roy

Advancements in artificial intelligence for molecular science are necessitating a paradigm shift from purely data-driven predictions to knowledge-guided computational reasoning. Existing molecular models are predominantly proprietary,…

Machine Learning · Computer Science 2026-03-16 Pengfei Liu , Shuang Ge , Jun Tao , Zhixiang Ren

Large language models (LLMs) holds significant promise in achieving general medication recommendation systems owing to their comprehensive interpretation of clinical notes and flexibility to medication encoding. We evaluated both…

Information Retrieval · Computer Science 2025-08-05 Zihao Zhao , Chenxiao Fan , Junlong Liu , Zheng Wang , Xiangnan He , Chongming Gao , Juan Li , Fuli Feng

Molecule generation and optimization is a fundamental task in chemical domain. The rapid development of intelligent tools, especially large language models (LLMs) with powerful knowledge reserves and interactive capabilities, has provided…

Machine Learning · Computer Science 2026-02-10 Haoran Liu , Zheni Zeng , Yukun Yan , Yuxuan Chen , Yunduo Xiao

This paper investigates the automation of qualitative data analysis, focusing on inductive coding using large language models (LLMs). Unlike traditional approaches that rely on deductive methods with predefined labels, this research…

Computation and Language · Computer Science 2025-12-02 Angelina Parfenova , Andreas Marfurt , Alexander Denzler , Juergen Pfeffer

The application of language models (LMs) to molecular structure generation using line notations such as SMILES and SELFIES has been well-established in the field of cheminformatics. However, extending these models to generate 3D molecular…

Machine Learning · Computer Science 2024-12-03 Kaiyuan Gao , Yusong Wang , Haoxiang Guan , Zun Wang , Qizhi Pei , John E. Hopcroft , Kun He , Lijun Wu

Background: Structured information extraction from unstructured histopathology reports facilitates data accessibility for clinical research. Manual extraction by experts is time-consuming and expensive, limiting scalability. Large language…

Large Language Models (LLMs) have emerged as transformative tools in the healthcare sector, demonstrating remarkable capabilities in natural language understanding and generation. However, their proficiency in numerical reasoning,…

Artificial Intelligence · Computer Science 2025-01-27 Arjun R. Malghan

Systematic reviews traditionally have taken considerable amounts of human time and energy to complete, in part due to the extensive number of titles and abstracts that must be reviewed for potential inclusion. Recently, researchers have…

Computation and Language · Computer Science 2026-03-27 Kweku Yamoah , Noah Schroeder , Emmanuel Dorley , Neha Rani , Caleb Schutz

Large language models offer a scalable alternative to human coding for data annotation tasks, enabling the scale-up of research across data-intensive domains. While LLMs are already achieving near-human accuracy on objective annotation…

Computation and Language · Computer Science 2026-01-21 Zhen Xu , Vedant Khatri , Yijun Dai , Xiner Liu , Siyan Li , Xuanming Zhang , Renzhe Yu

Large Language Models (LLM) are increasingly used for software development, yet existing benchmarks for LLM-based coding assistance do not reflect the constraints of High Energy Physics (HEP) and High Performance Computing (HPC) software.…

Large Language Models (LLMs) are unable to reliably reason about specific physical systems. Attempts to imbue LLMs with knowledge of the necessary physics concepts have shown great promise, but explainability and validation remain open…

Artificial Intelligence · Computer Science 2026-05-22 Sean Memery , Kartic Subr

Evaluating production-level retrieval systems at scale is a crucial yet challenging task due to the limited availability of a large pool of well-trained human annotators. Large Language Models (LLMs) have the potential to address this…

Information Retrieval · Computer Science 2024-09-19 Kasra Hosseini , Thomas Kober , Josip Krapac , Roland Vollgraf , Weiwei Cheng , Ana Peleteiro Ramallo

Recent developments show that Large Language Models (LLMs) produce state-of-the-art performance on natural language (NL) to code generation for resource-rich general-purpose languages like C++, Java, and Python. However, their practical…

Large language models (LLMs) perform well at a myriad of tasks, but explaining the processes behind this performance is a challenge. This paper investigates whether LLMs can give faithful high-level explanations of their own internal…

Machine Learning · Computer Science 2024-05-14 Dane Sherburn , Bilal Chughtai , Owain Evans

As Large Language Model (LLM) capabilities advance, the demand for high-quality annotation of exponentially increasing text corpora has outpaced human capacity, leading to the widespread adoption of LLMs in automatic evaluation and…

Computation and Language · Computer Science 2026-04-02 Jiayu Wang , Junyoung Lee

Generating long, coherent text remains a challenge for large language models (LLMs), as they lack hierarchical planning and structured organization in discourse generation. We introduce Structural Alignment, a novel method that aligns LLMs…

Computation and Language · Computer Science 2026-02-04 Zae Myung Kim , Anand Ramachandran , Farideh Tavazoee , Joo-Kyung Kim , Oleg Rokhlenko , Dongyeop Kang

Traditional AI methods often rely on task-specific model designs and training, which constrain both the scalability of model size and generalization across different tasks. Here, we introduce ChemFM, a large foundation model specifically…

Computational Engineering, Finance, and Science · Computer Science 2025-11-06 Feiyang Cai , Katelin Zacour , Tianyu Zhu , Tzuen-Rong Tzeng , Yongping Duan , Ling Liu , Srikanth Pilla , Gang Li , Feng Luo