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This work develops a block aggregation approach to spatial estimation and prediction when the response is observed at a coarse spatial scale, for example as counts of events in administrative areas, or blocks, while covariates are available…

We propose the orthogonal random forest, an algorithm that combines Neyman-orthogonality to reduce sensitivity with respect to estimation error of nuisance parameters with generalized random forests (Athey et al., 2017)--a flexible…

Machine Learning · Computer Science 2019-09-27 Miruna Oprescu , Vasilis Syrgkanis , Zhiwei Steven Wu

Interactions between genes and environmental factors may play a key role in the etiology of many common disorders. Several regularized generalized linear models (GLMs) have been proposed for hierarchical selection of gene by environment…

Methodology · Statistics 2023-12-22 Julien St-Pierre , Karim Oualkacha , Julien St-Pierre

We introduce a modification of Random Forests to estimate functions when unobserved confounding variables are present. The technique is tailored for high-dimensional settings with many observed covariates. We use spectral deconfounding…

Computation · Statistics 2025-09-25 Markus Ulmer , Cyrill Scheidegger , Peter Bühlmann

An algorithm to improve performance parameter for unsupervised decision forest clustering and density estimation is presented. Specifically, a dual assignment parameter is introduced as a density estimator by combining Random Forest and…

Computer Vision and Pattern Recognition · Computer Science 2015-07-19 Hayder Albehadili , Naz Islam

A key challenge in estimating causal effects from observational data is handling confounding and is commonly achieved through weighting methods that balance distribution of covariates between treatment and control groups. Weighting…

Methodology · Statistics 2025-12-23 Simion De , Jared D. Huling

Most epidemic models are spatially aggregate and the index which is most used for planning and policy numbers, the r number, typically refers to a single system of interest. Even if r numbers are calculated for each of adjacent areas,…

Physics and Society · Physics 2020-05-18 Alan Wilson

Spatial confounding is a common issue in spatial regression models, occurring when spatially varying covariates correlate with the spatial effect included in the model. This dependence, particularly at high spatial frequencies, can…

Methodology · Statistics 2025-12-16 Isa Marques , Paul F. V. Wiemann

Containment of epidemic outbreaks entails great societal and economic costs. Cost-effective containment strategies rely on efficiently identifying infected individuals, making the best possible use of the available testing resources.…

Populations and Evolution · Quantitative Biology 2020-12-01 Laura Natali , Saga Helgadottir , Onofrio M. Marago , Giovanni Volpe

To address the dual challenges of inherent stochasticity and non-differentiable metrics in physical spatiotemporal forecasting, we propose Spatiotemporal Forecasting as Planning (SFP), a new paradigm grounded in Model-Based Reinforcement…

Machine Learning · Computer Science 2025-10-13 Hao Wu , Yuan Gao , Xingjian Shi , Shuaipeng Li , Fan Xu , Fan Zhang , Zhihong Zhu , Weiyan Wang , Xiao Luo , Kun Wang , Xian Wu , Xiaomeng Huang

Spatial scan statistics are well-known methods for cluster detection and are widely used in epidemiology and medical studies for detecting and evaluating the statistical significance of disease hotspots. For the sake of simplicity, the…

Methodology · Statistics 2019-11-25 Mohamed-Salem Ahmed , Lionel Cucala , Michael Genin

We consider design-based causal inference for spatial experiments in which treatments may have effects that bleed out and feed back in complex ways. Such spatial spillover effects violate the standard ``no interference'' assumption for…

Methodology · Statistics 2024-08-06 Ye Wang , Cyrus Samii , Haoge Chang , P. M. Aronow

Flexible machine learning tools are increasingly used to estimate heterogeneous treatment effects. This paper gives an accessible tutorial demonstrating the use of the causal forest algorithm, available in the R package grf. We start with a…

Applications · Statistics 2024-12-17 Erik Sverdrup , Maria Petukhova , Stefan Wager

Random forests are a learning algorithm proposed by Breiman [Mach. Learn. 45 (2001) 5--32] that combines several randomized decision trees and aggregates their predictions by averaging. Despite its wide usage and outstanding practical…

Statistics Theory · Mathematics 2015-08-11 Erwan Scornet , Gérard Biau , Jean-Philippe Vert

Fine particulate matter and aerosol optical thickness are of interest to atmospheric scientists for understanding air quality and its various health/environmental impacts. The available data are extremely large, making uncertainty…

Methodology · Statistics 2025-03-05 Madelyn Clinch , Jonathan R. Bradley

Estimating associations between spatial covariates and responses - rather than merely predicting responses - is central to environmental science, epidemiology, and economics. For instance, public health officials might be interested in…

Machine Learning · Statistics 2025-11-11 David R. Burt , Renato Berlinghieri , Stephen Bates , Tamara Broderick

Public health data are often spatially dependent, but standard spatial regression methods can suffer from bias and invalid inference when the independent variable is associated with spatially-correlated residuals. This could occur if, for…

Methodology · Statistics 2025-04-10 Nate Wiecha , Jane A. Hoppin , Brian J. Reich

The emergence of novel infectious agents presents challenges to statistical models of disease transmission. These challenges arise from limited, poor-quality data and an incomplete understanding of the agent. Moreover, outbreaks manifest…

Methodology · Statistics 2024-03-20 Jiasheng Shi , Jeffrey S. Morris , David M. Rubin , Jing Huang

Background: Reliable prediction of clinical progression over time can improve the outcomes of depression. Little work has been done integrating various risk factors for depression, to determine the combinations of factors with the greatest…

Machine Learning · Statistics 2023-07-06 Runa Bhaumik , Jonathan Stange

Data fusion models are widely used in air quality monitoring to integrate in situ and large-scale gridded products, offering spatially complete and temporally detailed estimates. However, traditional Gaussian-based models often…

Applications · Statistics 2026-05-18 M. Daniela Cuba , Craig Wilkie , Marian Scott , Daniela Castro-Camilo
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