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Background: Coronary Artery Disease (CAD) is one of the leading causes of death worldwide. Invasive Coronary Angiography (ICA), regarded as the gold standard for CAD diagnosis, necessitates precise vessel segmentation and stenosis…

Computer Vision and Pattern Recognition · Computer Science 2025-09-15 Nan Mu , Ruiqi Song , Zhihui Xu , Jingfeng Jiang , Chen Zhao

Accurate multi-class segmentation is a long-standing challenge in medical imaging, especially in scenarios where classes share strong similarity. Segmenting retinal blood vessels in retinal photographs is one such scenario, in which…

Image and Video Processing · Electrical Eng. & Systems 2021-12-10 Yukun Zhou , Moucheng Xu , Yipeng Hu , Hongxiang Lin , Joseph Jacob , Pearse A. Keane , Daniel C. Alexander

Accurate segmentation of coronary arteries from computed tomography angiography (CTA) images is of paramount clinical importance for the diagnosis and treatment planning of cardiovascular diseases. However, coronary artery segmentation…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Xiaochan Yuan , Pai Zeng

Coronary artery disease stands as one of the primary contributors to global mortality rates. The automated identification of coronary artery stenosis from X-ray images plays a critical role in the diagnostic process for coronary heart…

Image and Video Processing · Electrical Eng. & Systems 2025-04-22 Ali Rostami , Fatemeh Fouladi , Hedieh Sajedi

How to accurately classify and diagnose whether an individual has Coronary Stenosis (CS) without invasive physical examination? This problem has not been solved satisfactorily. To this end, the four machine learning (ML) algorithms, i.e.,…

Tissues and Organs · Quantitative Biology 2021-09-08 Weijun Zhu , Fengyuan Lu , Xiaoyu Yang , En Li

Assessing the severity of stenoses in coronary angiography is critical to the patient's health, as coronary stenosis is an underlying factor in heart failure. Current practice for grading coronary lesions, i.e. fractional flow reserve (FFR)…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Raffaele Mineo , Amelia Sorrenti , Federica Proietto Salanitri

Accurate segmentation of the ventricles from cardiac magnetic resonance images (CMRIs) is crucial for enhancing the diagnosis and analysis of heart conditions. Deep learning-based segmentation methods have recently garnered significant…

Image and Video Processing · Electrical Eng. & Systems 2025-03-26 Hong Zheng , Yucheng Chen , Nan Mu , Xiaoning Li

Multiple instance learning (MIL) is a powerful tool to solve the weakly supervised classification in whole slide image (WSI) based pathology diagnosis. However, the current MIL methods are usually based on independent and identical…

Computer Vision and Pattern Recognition · Computer Science 2021-11-02 Zhuchen Shao , Hao Bian , Yang Chen , Yifeng Wang , Jian Zhang , Xiangyang Ji , Yongbing Zhang

Coronary angiography continues to serve as the primary method for diagnosing coronary artery disease (CAD), which is the leading global cause of mortality. The severity of CAD is quantified by the location, degree of narrowing (stenosis),…

Image and Video Processing · Electrical Eng. & Systems 2023-10-24 Hui Lin , Tom Liu , Aggelos Katsaggelos , Adrienne Kline

Various types of atherosclerotic plaque and varying grades of stenosis could lead to different management of patients with coronary artery disease. Therefore, it is crucial to detect and classify the type of coronary artery plaque, as well…

Computer Vision and Pattern Recognition · Computer Science 2018-12-11 Majd Zreik , Robbert W. van Hamersvelt , Jelmer M. Wolterink , Tim Leiner , Max A. Viergever , Ivana Isgum

Hispathological image segmentation algorithms play a critical role in computer aided diagnosis technology. The development of weakly supervised segmentation algorithm alleviates the problem of medical image annotation that it is…

Computer Vision and Pattern Recognition · Computer Science 2022-05-19 Ziniu Qian , Kailu Li , Maode Lai , Eric I-Chao Chang , Bingzheng Wei , Yubo Fan , Yan Xu

Retinal vessel segmentation plays a vital role in analyzing fundus images for the diagnosis of systemic and ocular diseases. Building on this, classifying segmented vessels into arteries and veins (A/V) further enables the extraction of…

Image and Video Processing · Electrical Eng. & Systems 2025-08-07 Shuang Zeng , Chee Hong Lee , Kaiwen Li , Boxu Xie , Ourui Fu , Hangzhou He , Lei Zhu , Yanye Lu , Fangxiao Cheng

Vascular structures in the retina contain important information for the detection and analysis of ocular diseases, including age-related macular degeneration, diabetic retinopathy and glaucoma. Commonly used modalities in diagnosis of these…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Erick O. Rodrigues , Aura Conci , Panos Liatsis

Cardio-cerebrovascular diseases are the leading causes of mortality worldwide, whose accurate blood vessel segmentation is significant for both scientific research and clinical usage. However, segmenting cardio-cerebrovascular structures…

Image and Video Processing · Electrical Eng. & Systems 2024-04-03 Nazik Elsayed , Yousuf Babiker M. Osman , Cheng Li , Jiong Zhang , Shanshan Wang

Segmenting of clinically important retinal blood vessels into arteries and veins is a prerequisite for retinal vessel analysis. Such analysis can provide potential insights and bio-markers for identifying and diagnosing various retinal eye…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Sharan SK , Subin Sahayam , Umarani Jayaraman , Lakshmi Priya A

This study presents an application of machine learning (ML) methods for detecting the presence of stenoses and aneurysms in the human arterial system. Four major forms of arterial disease -- carotid artery stenosis (CAS), subclavian artery…

Machine Learning · Computer Science 2021-08-03 Gareth Jones , Jim Parr , Perumal Nithiarasu , Sanjay Pant

Automatic diagnosis of coronary heart disease helps the doctor to support in decision making a diagnosis. Coronary heart disease have some types or levels. Referring to the UCI Repository dataset, it divided into 4 types or levels that are…

Machine Learning · Computer Science 2015-11-17 Wiharto Wiharto , Hari Kusnanto , Herianto Herianto

Multiple instance learning (MIL) is a robust paradigm for whole-slide pathological image (WSI) analysis, processing gigapixel-resolution images with slide-level labels. As pioneering efforts, attention-based MIL (ABMIL) and its variants are…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Linghan Cai , Shenjin Huang , Ye Zhang , Jinpeng Lu , Yongbing Zhang

Scoliosis is a spinal curvature disorder that is difficult to detect early and can compress the chest cavity, impacting respiratory function and cardiac health. Especially for adolescents, delayed detection and treatment result in worsening…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Haiqing Li , Yuzhi Guo , Feng Jiang , Qifeng Zhou , Hehuan Ma , Junzhou Huang

In stable coronary artery disease (CAD), reduction in mortality and/or myocardial infarction with revascularization over medical therapy has not been reliably achieved. Coronary arteries are usually extracted to perform stenosis detection.…

Image and Video Processing · Electrical Eng. & Systems 2021-01-26 Chen Zhao , Haipeng Tang , Daniel McGonigle , Zhuo He , Chaoyang Zhang , Yu-Ping Wang , Hong-Wen Deng , Robert Bober , Weihua Zhou