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Whole slide pathology image classification presents challenges due to gigapixel image sizes and limited annotation labels, hindering model generalization. This paper introduces a prompt learning method to adapt large vision-language models…

Computational pathology (CPath) digitizes pathology slides into whole slide images (WSIs), enabling analysis for critical healthcare tasks such as cancer diagnosis and prognosis. However, WSIs possess extremely long sequence lengths (up to…

Computer Vision and Pattern Recognition · Computer Science 2025-12-04 Wenhao Tang , Heng Fang , Ge Wu , Xiang Li , Ming-Ming Cheng

Cancer subtyping is one of the most challenging tasks in digital pathology, where Multiple Instance Learning (MIL) by processing gigapixel whole slide images (WSIs) has been in the spotlight of recent research. However, MIL approaches do…

Even though convolutional neural networks (CNNs) are driving progress in medical image segmentation, standard models still have some drawbacks. First, the use of multi-scale approaches, i.e., encoder-decoder architectures, leads to a…

Computer Vision and Pattern Recognition · Computer Science 2020-02-18 Ashish Sinha , Jose Dolz

Whole-slide image (WSI) analysis is challenging due to the gigapixel scale of slides and their inherent hierarchical multi-resolution structure. Existing multiple instance learning (MIL) approaches often model WSIs as unordered collections…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Dongqing Xie , Yonghuang Wu

Feature pyramid network (FPN) based models, which fuse the semantics and salient details in a progressive manner, have been proven highly effective in salient object detection. However, it is observed that these models often generate…

Computer Vision and Pattern Recognition · Computer Science 2021-05-12 Zun Li , Congyan Lang , Junhao Liew , Qibin Hou , Yidong Li , Jiashi Feng

Foundation models have recently emerged as powerful feature extractors in computational pathology, yet they typically omit mechanisms for leveraging the global spatial structure of tissues and the local contextual relationships among…

Saliency prediction can benefit from training that involves scene understanding that may be tangential to the central task; this may include understanding places, spatial layout, objects or involve different datasets and their bias. One can…

Computer Vision and Pattern Recognition · Computer Science 2019-03-12 Sen Jia , Neil D. B. Bruce

Restoring reasonable and realistic content for arbitrary missing regions in images is an important yet challenging task. Although recent image inpainting models have made significant progress in generating vivid visual details, they can…

Computer Vision and Pattern Recognition · Computer Science 2023-06-06 Wendong Zhang , Yunbo Wang , Bingbing Ni , Xiaokang Yang

Dense pixel matching is required for many computer vision algorithms such as disparity, optical flow or scene flow estimation. Feature Pyramid Networks (FPN) have proven to be a suitable feature extractor for CNN-based dense matching tasks.…

Computer Vision and Pattern Recognition · Computer Science 2020-06-23 Rishav , René Schuster , Ramy Battrawy , Oliver Wasenmüller , Didier Stricker

Deep learning for medical image classification faces three major challenges: 1) the number of annotated medical images for training are usually small; 2) regions of interest (ROIs) are relatively small with unclear boundaries in the whole…

Computer Vision and Pattern Recognition · Computer Science 2019-10-23 Shaohua Li , Yong Liu , Xiuchao Sui , Cheng Chen , Gabriel Tjio , Daniel Shu Wei Ting , Rick Siow Mong Goh

Attention-based multiple instance learning (MIL) has emerged as a powerful framework for whole slide image (WSI) diagnosis, leveraging attention to aggregate instance-level features into bag-level predictions. Despite this success, we find…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Linfeng Ye , Shayan Mohajer Hamidi , Zhixiang Chi , Guang Li , Mert Pilanci , Takahiro Ogawa , Miki Haseyama , Konstantinos N. Plataniotis

Deep neural networks are increasingly applied in automated histopathology. Yet, whole-slide images (WSIs) are often acquired at gigapixel sizes, rendering them computationally infeasible to analyze entirely at high resolution. Diagnostic…

Image and Video Processing · Electrical Eng. & Systems 2026-02-10 Tarun G , Naman Malpani , Gugan Thoppe , Sridharan Devarajan

Multispectral imaging (MSI) captures data across multiple spectral bands, offering enhanced informational depth compared to standard RGB imaging and benefiting diverse fields such as agriculture, medical diagnostics, and industrial…

Instrumentation and Detectors · Physics 2025-08-29 Muchen Zhu , Baolei Liu , Yao Wang , Linjun Zhai , Jiaqi Song , Nana Liu , Zhaohua Yang , Lei Ding , Fan Wang

Multiple instance learning (MIL) is often used in medical imaging to classify high-resolution 2D images by processing patches or classify 3D volumes by processing slices. However, conventional MIL approaches treat instances separately,…

Machine Learning · Computer Science 2025-11-13 Ethan Harvey , Dennis Johan Loevlie , Michael C. Hughes

We present an application of Physics-Informed Neural Networks to handle MultiPhase-Field simulations of microstructure evolution. It has been showcased that a combination of optimization techniques extended and adapted from the PINNs…

Materials Science · Physics 2024-09-04 Seifallah Elfetni , Reza Darvishi Kamachali

Multiple instance learning (MIL) has emerged as a powerful framework for weakly supervised whole slide image (WSI) classification, enabling slide-level predictions without requiring detailed patch-level annotations. Despite its success, a…

Computer Vision and Pattern Recognition · Computer Science 2025-07-25 Bryan Wong , Mun Yong Yi

Convolutional Neural Networks (CNNs) have advanced significantly in visual representation learning and recognition. However, they face notable challenges in performance and computational efficiency when dealing with real-world, multi-scale…

Computer Vision and Pattern Recognition · Computer Science 2024-03-28 Wenzhuo Liu , Fei Zhu , Cheng-Lin Liu

Multi-instance learning is common for computer vision tasks, especially in biomedical image processing. Traditional methods for multi-instance learning focus on designing feature aggregation methods and multi-instance classifiers, where the…

Computer Vision and Pattern Recognition · Computer Science 2021-03-18 Yanlun Tu , Houchao Lei , Wei Long , Yang Yang

Digital pathology has revolutionized the field by enabling the digitization of tissue samples into whole slide images (WSIs). However, the high resolution and large size of WSIs present significant challenges when it comes to applying Deep…

Computer Vision and Pattern Recognition · Computer Science 2025-07-03 Ali Mammadov , Loïc Le Folgoc , Guillaume Hocquet , Pietro Gori