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Large language models (LLMs) have shown promise in clinical diagnosis but remain limited by unreliable report generation, weak evidence grounding, and opaque reasoning. We propose MedCollab, an IBIS-guided multi-agent framework for…

Multiagent Systems · Computer Science 2026-05-27 Yuqi Zhan , Xinyue Wu , Tianyu Lin , Yutong Bao , Xiaoyu Wang , Weihao Cheng , Huangwei Chen , Feiwei Qin , Zhu Zhu

Large language models (LLMs) have shown promise in medical domains, but their ability to handle specialized neurological reasoning requires systematic evaluation. We developed a comprehensive benchmark using 305 questions from Israeli Board…

Information Retrieval · Computer Science 2025-08-21 Moran Sorka , Alon Gorenshtein , Dvir Aran , Shahar Shelly

Predicting future clinical outcomes from electronic health records (EHR) remains challenging due to the complexity and heterogeneity of patient data. LLMs have shown strong potential for such predictive tasks, yet existing approaches mainly…

Computation and Language · Computer Science 2026-05-05 Yushi Cao , Yiming Chen , Hongchao Jiang , Hung-yi Lee , Robby T. Tan

We introduce ColaCare, a framework that enhances Electronic Health Record (EHR) modeling through multi-agent collaboration driven by Large Language Models (LLMs). Our approach seamlessly integrates domain-specific expert models with LLMs to…

Machine learning (ML) has the potential to revolutionize various domains, but its adoption is often hindered by the disconnect between the needs of domain experts and translating these needs into robust and valid ML tools. Despite recent…

Machine Learning · Computer Science 2025-12-22 Evgeny Saveliev , Jiashuo Liu , Nabeel Seedat , Anders Boyd , Mihaela van der Schaar

Large Language Models (LLMs) are increasingly deployed as reasoning systems, where reasoning paradigms - such as Chain-of-Thought (CoT) and multi-agent systems (MAS) - play a critical role, yet their relative effectiveness and cost-accuracy…

Machine Learning · Computer Science 2026-01-21 Yapeng Li , Jiakuo Yu , Zhixin Liu , Xinnan Liu , Jing Yu , Songze Li , Tonghua Su

Objective: Electronic medical records (EMRs) contain an amount of medical knowledge which can be used for clinical decision support (CDS). Our objective is a general system that can extract and represent these knowledge contained in EMRs to…

Artificial Intelligence · Computer Science 2017-09-21 Chao Zhao , Jingchi Jiang , Yi Guan

Large language models (LLMs) offer new opportunities for constructing knowledge graphs (KGs) from unstructured clinical narratives. However, existing approaches often rely on structured inputs and lack robust validation of factual accuracy…

Artificial Intelligence · Computer Science 2026-01-06 Udiptaman Das , Krishnasai B. Atmakuri , Duy Ho , Chi Lee , Yugyung Lee

Artificial intelligence has significantly advanced healthcare, particularly through large language models (LLMs) that excel in medical question answering benchmarks. However, their real-world clinical application remains limited due to the…

Computation and Language · Computer Science 2024-07-01 Zhihao Fan , Jialong Tang , Wei Chen , Siyuan Wang , Zhongyu Wei , Jun Xi , Fei Huang , Jingren Zhou

Retrieval-augmented generation (RAG) has emerged as a promising approach to enhance the performance of large language models (LLMs) in knowledge-intensive tasks such as those from medical domain. However, the sensitive nature of the medical…

Computation and Language · Computer Science 2024-11-15 Nghia Trung Ngo , Chien Van Nguyen , Franck Dernoncourt , Thien Huu Nguyen

In-context learning (ICL) with large language models (LLMs) has emerged as a promising paradigm for named entity recognition (NER) in low-resource scenarios. However, existing ICL-based NER methods suffer from three key limitations: (1)…

Computation and Language · Computer Science 2025-11-25 Wenxuan Mu , Jinzhong Ning , Di Zhao , Yijia Zhang

Systematic reviews (SR), in which experts summarize and analyze evidence across individual studies to provide insights on a specialized topic, are a cornerstone for evidence-based clinical decision-making, research, and policy. Given the…

Computation and Language · Computer Science 2025-05-30 Christopher Polzak , Alejandro Lozano , Min Woo Sun , James Burgess , Yuhui Zhang , Kevin Wu , Serena Yeung-Levy

The recent advancement of Multimodal Large Language Models (MLLMs) is transforming human-computer interaction (HCI) from surface-level exchanges into more nuanced and emotionally intelligent communication. To realize this shift, emotion…

Artificial Intelligence · Computer Science 2026-01-06 Hyeongseop Rha , Jeong Hun Yeo , Yeonju Kim , Yong Man Ro

Large language models (LLMs) are transforming the landscape of medicine, yet two fundamental challenges persist: keeping up with rapidly evolving medical knowledge and providing verifiable, evidence-grounded reasoning. Retrieval-augmented…

Machine reasoning has made great progress in recent years owing to large language models (LLMs). In the clinical domain, however, most NLP-driven projects mainly focus on clinical classification or reading comprehension, and under-explore…

Computation and Language · Computer Science 2024-05-13 Taeyoon Kwon , Kai Tzu-iunn Ong , Dongjin Kang , Seungjun Moon , Jeong Ryong Lee , Dosik Hwang , Yongsik Sim , Beomseok Sohn , Dongha Lee , Jinyoung Yeo

Large language models (LLMs) incorporated with Retrieval-Augmented Generation (RAG) have demonstrated powerful capabilities in generating counterspeech against misinformation. However, current studies rely on limited evidence and offer less…

Computation and Language · Computer Science 2025-09-16 Anirban Saha Anik , Xiaoying Song , Elliott Wang , Bryan Wang , Bengisu Yarimbas , Lingzi Hong

Multimodal large language models (MLLMs) demonstrate considerable potential in clinical diagnostics, a domain that inherently requires synthesizing complex visual and textual data alongside consulting authoritative medical literature.…

Computation and Language · Computer Science 2026-03-23 Yannian Gu , Zhongzhen Huang , Linjie Mu , Xizhuo Zhang , Shaoting Zhang , Xiaofan Zhang

In today's world, emotional support is increasingly essential, yet it remains challenging for both those seeking help and those offering it. Multimodal approaches to emotional support show great promise by integrating diverse data sources…

Large vision-language models (LVMs) hold a great promise for automating medical report generation, potentially reducing the burden of manual reporting. State-of-the-art (SOTA) research fine-tunes general LVMs with medical data to align…

Computation and Language · Computer Science 2025-04-07 Hao Wang , Shuchang Ye , Jinghao Lin , Usman Naseem , Jinman Kim

Automating radiology report generation poses a dual challenge: building clinically reliable systems and designing rigorous evaluation protocols. We introduce a multi-agent reinforcement learning framework that serves as both a benchmark and…

Artificial Intelligence · Computer Science 2025-09-23 Ahmed T. Elboardy , Ghada Khoriba , Essam A. Rashed