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Acquiring high-contrast optical images deep inside biological tissues is still a challenging problem. Confocal microscopy is an important tool for biomedical imaging since it improves image quality by rejecting background signals. However,…

In ultrasound (US) imaging, various types of adaptive beamforming techniques have been investigated to improve the resolution and contrast-to-noise ratio of the delay and sum (DAS) beamformers. Unfortunately, the performance of these…

Image and Video Processing · Electrical Eng. & Systems 2020-02-25 Shujaat Khan , Jaeyoung Huh , Jong Chul Ye

Wavefront shaping allows focusing light through or inside strongly scattering media, but the background intensity also increases due to long-range correlations, reducing the target's contrast. By manipulating non-local intensity…

Biological tissues are composed of discrete compartments of biochemical media that often exhibit subtle differences in refractive index. Light propagating through these compartments partially diffracts in a forward direction with a pi/2…

Optics · Physics 2025-05-12 Gregory N. McKay , Jerome Mertz , Nicholas J. Durr

Biomedical photoacoustic tomography, which can provide high resolution 3D soft tissue images based on the optical absorption, has advanced to the stage at which translation from the laboratory to clinical settings is becoming possible. The…

Image and Video Processing · Electrical Eng. & Systems 2020-11-20 Andreas Hauptmann , Ben Cox

Optical-resolution fluorescence imaging through and within complex samples presents a significant challenge due to random light scattering, with substantial implications across multiple fields. While significant advancements in coherent…

Optics · Physics 2023-12-27 Gil Weinberg , Elad Sunray , Ori Katz

Deep fluorescence imaging in mammalian brain tissues remains challenging due to scattering and optical aberration-induced loss in signal and resolution. Correction of aberrations using adaptive optics (AO) requires their reliable…

Spherical matrix arrays arguably represent an advantageous tomographic detection geometry for non-invasive deep tissue mapping of vascular networks and oxygenation with volumetric optoacoustic tomography (VOT). Hybridization of VOT with…

Medical Physics · Physics 2021-01-05 Justine Robin , Ali Ozbek , Michael Reiss , Xose-Luis Dean-Ben , Daniel Razansky

Photoacoustic (PA) imaging has the potential to revolutionize functional medical imaging in healthcare due to the valuable information on tissue physiology contained in multispectral photoacoustic measurements. Clinical translation of the…

Enhancing forward-looking sonar images is critical for accurate underwater target detection. Current deep learning methods mainly rely on supervised training with simulated data, but the difficulty in obtaining high-quality real-world…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Zhisheng Zhang , Peng Zhang , Fengxiang Wang , Liangli Ma , Fuchun Sun

X-ray ptychography is a cutting edge imaging technique providing ultra-high spatial resolutions. In ptychography, phase retrieval, i.e., the recovery of a complex valued signal from intensity-only measurements, is enabled by exploiting a…

Image and Video Processing · Electrical Eng. & Systems 2022-09-14 Felix Wittwer , Peter Modregger

We propose approaches based on deep learning to localize objects in images when only a small training dataset is available and the images have low quality. That applies to many problems in medical image processing, and in particular to the…

Computer Vision and Pattern Recognition · Computer Science 2018-11-20 Aaron Pries , Peter J. Schreier , Artur Lamm , Stefan Pede , Jürgen Schmidt

Diffusion models have enabled remarkably high-quality medical image generation, yet it is challenging to enforce anatomical constraints in generated images. To this end, we propose a diffusion model-based method that supports…

Image and Video Processing · Electrical Eng. & Systems 2024-06-21 Nicholas Konz , Yuwen Chen , Haoyu Dong , Maciej A. Mazurowski

Sample-induced aberrations and optical imperfections limit the resolution of fluorescence microscopy. Phase diversity is a powerful technique that leverages complementary phase information in sequentially acquired images with deliberately…

Deformable medical image registration is a crucial aspect of medical image analysis. In recent years, researchers have begun leveraging auxiliary tasks (such as supervised segmentation) to provide anatomical structure information for the…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Hongchao Zhou , Shunbo Hu

The recent success of the generative model shows that leveraging the multi-modal embedding space can manipulate an image using text information. However, manipulating an image with other sources rather than text, such as sound, is not easy…

Graphics · Computer Science 2021-12-02 Seung Hyun Lee , Wonseok Roh , Wonmin Byeon , Sang Ho Yoon , Chan Young Kim , Jinkyu Kim , Sangpil Kim

High-dimensional entangled quantum states improve the performance of quantum technologies compared to qubit-based approaches. In particular, they enable quantum communications with higher information capacities or enhanced imaging…

Quantum Physics · Physics 2023-01-11 Baptiste Courme , Patrick Cameron , Daniele Faccio , Sylvain Gigan , Hugo Defienne

Photoacoustic imaging (PAI) is a powerful imaging modality that relies on the PA effect. PAI works on the principle of electromagnetic energy absorption by the exogenous contrast agents and/or endogenous molecules present in the biological…

Optics · Physics 2020-12-16 Mohsin Zafar , Qiuyun Xu , Rayyan Manwar

Studying the internal structure of complex samples with light is an important task, but a difficult challenge due to light scattering. While the complex optical distortions induced by multiple scattering can be effectively undone with the…

Optics · Physics 2019-10-04 Ori Katz , François Ramaz , Sylvain Gigan , Mathias Fink

Optical imaging plays a crucial role in advancing science and technology, enabling applications in fields ranging from biomedicine to astronomy. However, imaging through scattering media such as biological tissues, fog, or turbulent…

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