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Disease-modifying management aims to prevent deterioration and progression of the disease, not just relieve symptoms. Unfortunately, the development of necessary therapies is often hampered by the failure to recognize the presymptomatic…

The long-term evolution of epidemic processes depends crucially on the structure of contact networks. As empirical evidence indicates that human populations exhibit strong community organization, we investigate here how such mesoscopic…

Physics and Society · Physics 2016-11-09 T. Jesan , Chandrashekar Kuyyamudi , Sitabhra Sinha

Navigation of microorganisms is controlled by internal processes ultimately sensitive to mechanical or chemical signaling encountered along the path. In many natural environments, such as porous soils or physiological ducts, motile species…

Imaging through scattering media is a fundamental and pervasive challenge in fields ranging from medical diagnostics to astronomy. A promising strategy to overcome this challenge is wavefront modulation, which induces measurement diversity…

Computer Vision and Pattern Recognition · Computer Science 2024-04-12 Mingyang Xie , Haiyun Guo , Brandon Y. Feng , Lingbo Jin , Ashok Veeraraghavan , Christopher A. Metzler

The interactions between cells and the extracellular matrix are vital for the self-organisation of tissues. In this paper we present proof-of-concept to use machine learning tools to predict the role of this mechanobiology in the…

Tissues and Organs · Quantitative Biology 2023-04-03 Allison E. Andrews , Hugh Dickinson , James P. Hague

Macrophages play an essential role in wound healing due to their dynamic nature and functional plasticity, exhibiting highly heterogeneous morpho-kinetic behaviors depending on their activation states. However, quantitative analysis of…

Quantitative Methods · Quantitative Biology 2025-07-28 Seol Ah Park , Giulia Lupi , Resul Ozbilgic , Michal Kollar , Aneta A. Ozvat , Mai Nguyen-Chi , Karol Mikula

Anaerobic processes (e.g., methanogenesis and fermentation) largely contribute to element cycling and natural contaminant attenuation/mobilization, even in well-oxygenated porous environments, such as shallow aquifers. This paradox is…

Biological Physics · Physics 2022-11-24 Giulia Ceriotti , Sergey M. Borisov , Jasmine Berg , Pietro de Anna

Biological systems are promising substrates for computation because they naturally process environmental information through complex internal dynamics. In this study, we investigate whether bacterial metabolic models can act as physical…

Emerging Technologies · Computer Science 2026-04-23 Laura Alonso Bartolomé , Jean-Loup Faulon , Xavier Hinaut

Despite progress in deep learning for shared micromobility demand prediction, the systematic design and statistical validation of temporal input structures remain underexplored. Temporal features are often selected heuristically, even…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Mohammad Sahnoon , Merkebe Getachew Demissie , Roberto Souza

The accurate segmentation of medical images is a crucial step in obtaining reliable morphological statistics. However, training a deep neural network for this task requires a large amount of labeled data to ensure high-accuracy results. To…

Image and Video Processing · Electrical Eng. & Systems 2023-07-04 Xianjun Han , Qianqian Chen , Zhaoyang Xie , Xuejun Li , Hongyu Yang

This study presents a neural network-enhanced approach to modeling disease spread dynamics over time and space. Neural networks are used to estimate time-varying parameters, with two calibration methods explored: Approximate Bayesian…

Quantitative Methods · Quantitative Biology 2024-10-29 Randy L. Caga-anan

Accurate and reliable forecasting of epidemic incidences is critical for public health preparedness, yet it remains a challenging task due to complex nonlinear temporal dependencies and heterogeneous spatial interactions. Often, point…

Machine Learning · Statistics 2026-03-10 Rajdeep Pathak , Tanujit Chakraborty

Bacterial conglomerates such as biofilms and microcolonies are ubiquitous in nature and play an important role in industry and medicine. In contrast to well-mixed, diluted cultures routinely used in microbial research, bacteria in a…

Biological Physics · Physics 2017-01-13 Fred F. Farrell , Matti Gralka , Oskar Hallatschek , Bartlomiej Waclaw

The massive employment of computational models in network epidemiology calls for the development of improved inference methods for epidemic forecast. For simple compartment models, such as the Susceptible-Infected-Recovered model, Belief…

Physics and Society · Physics 2017-07-05 Jacopo Bindi , Alfredo Braunstein , Luca Dall'Asta

Irregular bone remodeling is associated with a number of bone diseases such as osteoporosis and multiple myeloma. Computational and mathematical modeling can aid in therapy and treatment as well as understanding fundamental biology.…

Quantitative Methods · Quantitative Biology 2023-02-14 Jason M. Graham , Bruce P. Ayati , Prem S. Ramakrishnan , James A. Martin

Remote sensing change detection is often challenged by spatial misalignment between bi-temporal images, especially when acquisitions are separated by long seasonal or multi-year gaps. While modern convolutional and transformer-based models…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Seyedehanita Madani , Vishal M. Patel

This study investigates the role of spatial segregation, prompted by competition avoidance, as a key mechanism for emergent coexistence within microbial communities. Recognizing these communities as complex adaptive systems, we challenge…

Physics and Society · Physics 2024-03-12 Mattia Mattei , Alex Arenas

Formation flight has a vast potential for aerial robot swarms in various applications. However, existing methods lack the capability to achieve fully autonomous large-scale formation flight in dense environments. To bridge the gap, we…

Robotics · Computer Science 2023-08-08 Lun Quan , Longji Yin , Tingrui Zhang , Mingyang Wang , Ruilin Wang , Sheng Zhong , Zhou Xin , Yanjun Cao , Chao Xu , Fei Gao

Understanding how species persist under interacting stressors is a central challenge in ecology. We develop a spatially explicit reaction-diffusion framework to investigate competing species in landscapes shaped by climate variability,…

Populations and Evolution · Quantitative Biology 2026-02-02 Ton Viet Ta

Electromagnetic environments are becoming increasingly complex and congested, creating a growing challenge for systems that rely on electromagnetic waves for communication, sensing, or imaging, particularly in reverberating environments.…

Applied Physics · Physics 2022-02-11 Benjamin W. Frazier , Thomas M. Antonsen , Steven M. Anlage , Edward Ott