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Mechanosensitive ion transport plays a central role in enabling living systems to perceive and adapt to their environment through the deformation of soft, embedded ion channels. In this work, we demonstrate that ion transport within a…

Soft Condensed Matter · Physics 2026-05-04 Mathieu Lizée , Zhijia Zhang , Baptiste Coquinot , Qian Yang , Lydéric Bocquet

Fundamental understanding of ionic transport at the nanoscale is essential for developing biosensors based on nanopore technology and new generation high-performance nanofiltration membranes for separation and purification applications. We…

Ion transport measurements are widely used as an indirect probe for various properties of confined electrolytes. It is generally assumed that the ion concentration in a nanoscale channel is equal to the ion concentration in the macroscopic…

Soft Condensed Matter · Physics 2023-04-05 Paul Robin , Adrien Delahais , Lydéric Bocquet , Nikita Kavokine

Nanofluidics, the field interested in flows at the smallest scales, has grown at a fast pace, reaching an ever finer control offluidic and ionic transport at the molecular level. Still, artificial pores are far from reaching the wealth of…

Soft Condensed Matter · Physics 2023-05-10 Paul Robin , Lydéric Bocquet

Nanofluidic transport is ubiquitous in natural systems from extra-cellular communication in biology to geological phenomena, and promotes the emergence of new technologies such as energy harvesting and water desalination. While experimental…

Soft Condensed Matter · Physics 2026-03-23 Aymeric Allemand , Anne-Laure Biance , Christophe Ybert , Laurent Joly

Data-driven modeling is becoming central to multiphase transport, electronics cooling, acoustic diagnostics, and thermal-fluid digital twins, but progress is limited by fragmented datasets and raw instrument files that are difficult to…

Nanofluidic memristive devices work with nanoscale pores and ions dissolved in water, which harness the ionic memory effect aiming to store and process information. These devices share the same charge carriers as biological systems and…

Materials Science · Physics 2026-04-22 Wenzhe Zhou , Dongjiao Ge , Ao Zhang , Jincheng Xu , Yu Ji , Yiran Gong , Wenchang Zhang , Jidong Li , Li Lin , Zhiping Xu , Pengzhan Sun

Mechanosensitive ion nanochannels regulate transport by undergoing conformational changes within nanopores. However, achieving precise control over these conformational states remains a major challenge for both artificial soft or solid…

Chemical Physics · Physics 2026-01-06 Ke Zhou

While most neuromorphic systems are based on nanoscale electronic devices, nature relies on ions for energy-efficient information processing. Therefore, finding memristive nanofluidic devices is a milestone toward realizing electrolytic…

Fine-tuned ion transport across nanoscale pores is key to many biological processes such as neurotransmission. Recent advances have enabled the confinement of water and ions to two dimensions, unveiling transport properties unreachable at…

Soft Condensed Matter · Physics 2023-01-18 P. Robin , T. Emmerich , A. Ismail , A. Niguès , Y. You , G. -H. Nam , A. Keerthi , A. Siria , A. K. Geim , B. Radha , L. Bocquet

Reliable and controllable switches are crucial in nanofluidics and iontronics. Ion channels in nature serve as a rich source of inspiration due to their intricate mechanisms modulated by stimuli like pressure, temperature, chemicals, and…

Mesoscale and Nanoscale Physics · Physics 2023-10-17 Gonçalo Paulo , Alberto Gubbiotti , Giovanni Di Muccio , Alberto Giacomello

Recent advance in nanotechnology has led to rapid advances in nanofluidics, which has been established as a reliable means for a wide variety of applications, including molecular separation, detection, crystallization and biosynthesis.…

Quantitative Methods · Quantitative Biology 2015-03-03 Jin Kyoung Park , Kelin Xia , Guo-Wei We

Ion transport in extremely narrow nanochannels has gained increasing interest in recent years due to its unique physical properties, and the technological advances that allow us to study them. It is tempting to approach this regime with the…

Soft Condensed Matter · Physics 2020-02-11 Amir Levy , J. Pedro de Souza , Martin Z Bazant

We present a novel open-source Python framework called NanoNET (Nanoscale Non-equilibrium Electron Transport) for modelling electronic structure and transport. Our method is based on the tight-binding method and non-equilibrium Green's…

Computational Physics · Physics 2020-12-02 M. V. Klymenko , J. A. Vaitkus , J. S. Smith , J. H. Cole

The transport properties of nanofluidic channels are usually studied under constant (DC) voltage or pressure driving. However, the frequency response under sinusoidal (AC) drivings offers rich insights into the time-dependent transport…

Mesoscale and Nanoscale Physics · Physics 2026-04-07 Baptiste Coquinot , Mathieu Lizée , Lydéric Bocquet , Nikita Kavokine

The movement of ionic solutions is an essential part of biology and technology. Fluidics, from nano- to micro- to microfluidics, is a burgeoning area of technology which is all about the movement of ionic solutions, on various scales. Many…

Quantitative Methods · Quantitative Biology 2018-06-08 Shixin Xu , Bob Eisenberg , Zilong Song , Huaxiong Huang

We study charge transport in an ionic solution in a confined nanoscale geometry in the presence of an externally applied electric field and immobile background charges. For a range of parameters, the ion current shows non-monotonic behavior…

Statistical Mechanics · Physics 2015-05-13 Punyabrata Pradhan , Yariv Kafri , Dov Levine

Nanofluidic systems exhibit transport characteristics that have made technological marvels such as desalination, energy harvesting, and highly sensitive biomolecule sensing possible by virtue of their ability to influence small currents due…

Fluid Dynamics · Physics 2023-08-22 John Sebastian , Yoav Green

Dynamic reconfiguration of charge carriers in confined ion-channels under electrical stimulation produces memory effects, where the internal resistance depends on history of the electric field. Vermiculite nanofluidic devices harness this…

Ion transporters in Nature exhibit a wealth of complex transport properties such as voltage gating, activation, and mechanosensitive behavior. When combined, such processes result in advanced ionic machines achieving active ion transport,…

Soft Condensed Matter · Physics 2020-05-08 Laetitia Jubin , Anthony R. Poggioli , Alessandro Siria , Lydéric Bocquet
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