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Related papers: POET: Protocol Optimization via Eligibility Tuning

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We propose a novel approach for using unsupervised boosting to create an ensemble of generative models, where models are trained in sequence to correct earlier mistakes. Our meta-algorithmic framework can leverage any existing base learner…

Machine Learning · Computer Science 2017-12-25 Aditya Grover , Stefano Ermon

Clinical trials are critical for drug development but often suffer from expensive and inefficient patient recruitment. In recent years, machine learning models have been proposed for speeding up patient recruitment via automatically…

Machine Learning · Computer Science 2023-07-20 Brandon Theodorou , Cao Xiao , Jimeng Sun

Language models often achieve higher accuracy when reasoning step-by-step in complex tasks. However, even when arriving at a correct final answer, their rationales are often logically unsound or inconsistent. This is a major issue when…

Artificial Intelligence · Computer Science 2023-11-09 Gabriel Poesia , Kanishk Gandhi , Eric Zelikman , Noah D. Goodman

An AI design framework was developed based on three core principles, namely understandability, trust, and usability. The framework was conceptualized by synthesizing evidence from the literature and by consulting with experts. The initial…

Human-Computer Interaction · Computer Science 2025-08-12 Mohammad Golam Kibria , Lauren Kucirka , Javed Mostafa

Clinical trial eligibility matching is a critical yet often labor-intensive and error-prone step in medical research, as it ensures that participants meet precise criteria for safe and reliable study outcomes. Recent advances in Natural…

Machine Learning · Computer Science 2025-03-04 Muhammad Talha Sharif , Abdul Rehman

Research must be reproducible in order to make an impact on science and to contribute to the body of knowledge in our field. Yet studies have shown that 70% of research from academic labs cannot be reproduced. In software engineering, and…

Software Engineering · Computer Science 2018-04-10 Clinton Woodson , Jane Huffman Hayes , Sarah Griffioen

Configuration optimization remains a critical bottleneck in machine learning, requiring coordinated tuning across model architecture, training strategy, feature engineering, and hyperparameters. Traditional approaches treat these dimensions…

Artificial Intelligence · Computer Science 2025-08-22 Yuxing Lu , Yucheng Hu , Nan Sun , Xukai Zhao

The design of high-performance optical systems remains a specialized domain gated by the limited availability of expert engineers, creating a bottleneck that stalls innovation despite the growing demand for imaging hardware. While deep…

Optics · Physics 2026-02-17 Roy Maman , David Ohana , Jacob Engelberg , Uriel Levy

We introduce a new rule-based optimization method for classification with constraints. The proposed method leverages column generation for linear programming, and hence, is scalable to large datasets. The resulting pricing subproblem is…

Machine Learning · Computer Science 2025-02-07 Tabea E. Röber , Adia C. Lumadjeng , M. Hakan Akyüz , Ş. İlker Birbil

Accurately typing entity mentions from text segments is a fundamental task for various natural language processing applications. Many previous approaches rely on massive human-annotated data to perform entity typing. Nevertheless,…

Computation and Language · Computer Science 2024-02-21 Yu Zhang , Yunyi Zhang , Yanzhen Shen , Yu Deng , Lucian Popa , Larisa Shwartz , ChengXiang Zhai , Jiawei Han

While representation alignment with self-supervised models has been shown to improve diffusion model training, its potential for enhancing inference-time conditioning remains largely unexplored. We introduce Representation-Aligned Guidance…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Nicolas Sereyjol-Garros , Ellington Kirby , Victor Letzelter , Victor Besnier , Nermin Samet

Molecule generation using generative AI is vital for drug discovery, yet class-specific datasets often contain fewer than 100 training examples. While fragment-based models handle limited data better than atom-based approaches, existing…

Artificial Intelligence · Computer Science 2025-11-27 Yuto Suzuki , Paul Awolade , Daniel V. LaBarbera , Farnoush Banaei-Kashani

We propose a simple and effective modeling framework for controlled generation of multiple, diverse outputs. We focus on the setting of generating the next sentence of a story given its context. As controllable dimensions, we consider…

Computation and Language · Computer Science 2020-06-03 Lifu Tu , Xiaoan Ding , Dong Yu , Kevin Gimpel

Large language models benefit from training with a large amount of unlabeled text, which gives them increasingly fluent and diverse generation capabilities. However, using these models for text generation that takes into account target…

Computation and Language · Computer Science 2021-09-16 Dian Yu , Zhou Yu , Kenji Sagae

Controllable generation is one of the key requirements for successful adoption of deep generative models in real-world applications, but it still remains as a great challenge. In particular, the compositional ability to generate novel…

Computer Vision and Pattern Recognition · Computer Science 2021-12-07 Weili Nie , Arash Vahdat , Anima Anandkumar

Lead sheets have become commonplace in generative music research, being used as an initial compressed representation for downstream tasks like multitrack music generation and automatic arrangement. Despite this, researchers have often…

Sound · Computer Science 2023-10-18 Zachary Novack , Nikita Srivatsan , Taylor Berg-Kirkpatrick , Julian McAuley

Test Driven Development (TDD) is one of the major practices of Extreme Programming for which incremental testing and refactoring trigger the code development. TDD has limited adoption in the industry, as it requires more code to be…

Software Engineering · Computer Science 2025-01-15 Moritz Mock , Jorge Melegati , Barbara Russo

Eliciting requirements for Business Intelligence (BI) systems remains a significant challenge, particularly in changing business environments. This paper introduces a novel AI-driven system, called AutoBIR, that leverages semantic search…

Software Engineering · Computer Science 2024-12-11 Nimrod Busany , Ethan Hadar , Hananel Hadad , Gil Rosenblum , Zofia Maszlanka , Okhaide Akhigbe , Daniel Amyot

Data engineering pipelines are essential - albeit costly - components of predictive analytics frameworks requiring significant engineering time and domain expertise for carrying out tasks such as data ingestion, preprocessing, feature…

Machine Learning · Computer Science 2025-05-22 Iman Kazemian , Paritosh Ramanan , Murat Yildirim

Generative AI has demonstrated strong potential in healthcare, from clinical decision support to patient-facing chatbots that improve outcomes. A critical challenge for deployment is effective human-AI communication, where content must be…

Computation and Language · Computer Science 2025-07-11 Hieu Tran , Zonghai Yao , Won Seok Jang , Sharmin Sultana , Allen Chang , Yuan Zhang , Hong Yu