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Segment Anything Model 2 (SAM 2), a prompt-driven foundation model extending SAM to both image and video domains, has shown superior zero-shot performance compared to its predecessor. Building on SAM's success in medical image segmentation,…

Computer Vision and Pattern Recognition · Computer Science 2025-02-06 Bin Xie , Hao Tang , Yan Yan , Gady Agam

Medical image segmentation is fundamental for biomedical discovery. Existing methods lack generalizability and demand extensive, time-consuming manual annotation for new clinical application. Here, we propose MedSAM-3, a text promptable…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Anglin Liu , Rundong Xue , Xu R. Cao , Yifan Shen , Yi Lu , Xiang Li , Qianqian Chen , Jintai Chen

Training segmentation models for medical images continues to be challenging due to the limited availability of data annotations. Segment Anything Model (SAM) is a foundation model that is intended to segment user-defined objects of interest…

Computer Vision and Pattern Recognition · Computer Science 2023-08-09 Maciej A. Mazurowski , Haoyu Dong , Hanxue Gu , Jichen Yang , Nicholas Konz , Yixin Zhang

Intelligent medical image segmentation methods are rapidly evolving and being increasingly applied, yet they face the challenge of domain transfer, where algorithm performance degrades due to different data distributions between source and…

Computer Vision and Pattern Recognition · Computer Science 2024-08-12 Andrew Seohwan Yu , Mohsen Hariri , Xuecen Zhang , Mingrui Yang , Vipin Chaudhary , Xiaojuan Li

Domain adaptive segmentation (DAS) of numerous organelle instances from large-scale electron microscopy (EM) is a promising way to enable annotation-efficient learning. Inspired by SAM, we propose a promptable multitask framework, namely…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Jiabao Chen , Shan Xiong , Jialin Peng

The success of Convolutional Neural Networks (CNNs) in 3D medical image segmentation relies on massive fully annotated 3D volumes for training that are time-consuming and labor-intensive to acquire. In this paper, we propose to annotate a…

Computer Vision and Pattern Recognition · Computer Science 2023-02-14 Shuwei Zhai , Guotai Wang , Xiangde Luo , Qiang Yue , Kang Li , Shaoting Zhang

Foundation models for image segmentation have shown strong generalization in natural images, yet their applicability to 3D medical imaging remains limited. In this work, we study the zero-shot use of Segment Anything Model 2 (SAM2) for…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Miquel Lopez Escoriza , Pau Amargant Alvarez

Segment Anything Model (SAM) has demonstrated impressive zero-shot performance and brought a range of unexplored capabilities to natural image segmentation tasks. However, as a very important branch of image segmentation, the performance of…

Computer Vision and Pattern Recognition · Computer Science 2025-02-04 Bin Xie , Hao Tang , Dawen Cai , Yan Yan , Gady Agam

The emerging scale segmentation model, Segment Anything (SAM), exhibits impressive capabilities in zero-shot segmentation for natural images. However, when applied to medical images, SAM suffers from noticeable performance drop. To make SAM…

Computer Vision and Pattern Recognition · Computer Science 2023-06-27 Xinrong Hu , Xiaowei Xu , Yiyu Shi

Promptable segmentation has emerged as a powerful paradigm in computer vision, enabling users to guide models in parsing complex scenes with prompts such as clicks, boxes, or textual cues. Recent advances, exemplified by the Segment…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Yoonwoo Jeong , Cheng Sun , Yu-Chiang Frank Wang , Minsu Cho , Jaesung Choe

Purpose: Accurate tumor segmentation is vital for adaptive radiation therapy (ART) but remains time-consuming and user-dependent. Segment Anything Model 2 (SAM2) shows promise for prompt-based segmentation but struggles with tumor accuracy.…

Image and Video Processing · Electrical Eng. & Systems 2025-07-28 Guoping Xu , Yan Dai , Hengrui Zhao , Ying Zhang , Jie Deng , Weiguo Lu , You Zhang

The reliance on large labeled datasets presents a significant challenge in medical image segmentation. Few-shot learning offers a potential solution, but existing methods often still require substantial training data. This paper proposes a…

Image and Video Processing · Electrical Eng. & Systems 2025-03-10 Haiyue Zu , Jun Ge , Heting Xiao , Jile Xie , Zhangzhe Zhou , Yifan Meng , Jiayi Ni , Junjie Niu , Linlin Zhang , Li Ni , Huilin Yang

Foundation models have shown strong performance in multi-object segmentation with visual prompts, yet histopathology images remain challenging due to high cellular density, heterogeneity, and the gap between pixel-level supervision and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Yonghuang Wu , Wenwen Zeng , Xuan Xie , Chengqian Zhao , Guoqing Wu , Jinhua Yu

3D image segmentation is one of the most important and ubiquitous problems in medical image processing. It provides detailed quantitative analysis for accurate disease diagnosis, abnormal detection, and classification. Currently deep…

Computer Vision and Pattern Recognition · Computer Science 2019-06-19 Zhenxi Zhang , Jie Li , Zhusi Zhong , Zhicheng Jiao , Xinbo Gao

Automated segmentation of cancer on medical images can aid targeted diagnostic and therapeutic procedures. However, its adoption is limited by the high cost of expert annotations required for training and inter-observer variability in…

Image and Video Processing · Electrical Eng. & Systems 2025-05-26 Lynn Karam , Yipei Wang , Veeru Kasivisvanathan , Mirabela Rusu , Yipeng Hu , Shaheer U. Saeed

**Background:** Accurate 3D CT scan segmentation of gastric tumors is pivotal for diagnosis and treatment. The challenges lie in the irregular shapes, blurred boundaries of tumors, and the inefficiency of existing methods. **Purpose:** We…

Image and Video Processing · Electrical Eng. & Systems 2023-05-30 Zifan Chen , Jiazheng Li , Jie Zhao , Yiting Liu , Hongfeng Li , Bin Dong , Lei Tang , Li Zhang

We introduce GeoSAM2, a prompt-controllable framework for 3D part segmentation that casts the task as multi-view 2D mask prediction. Given a textureless object, we render normal and point maps from predefined viewpoints and accept simple 2D…

Computer Vision and Pattern Recognition · Computer Science 2025-08-28 Ken Deng , Yunhan Yang , Jingxiang Sun , Xihui Liu , Yebin Liu , Ding Liang , Yan-Pei Cao

Segment Anything Model (SAM) has gained significant recognition in the field of semantic segmentation due to its versatile capabilities and impressive performance. Despite its success, SAM faces two primary limitations: (1) it relies…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Yuchen Li , Li Zhang , Youwei Liang , Pengtao Xie

Segmenting objects with complex shapes, such as wires, bicycles, or structural grids, remains a significant challenge for current segmentation models, including the Segment Anything Model (SAM) and its high-quality variant SAM-HQ. These…

Computer Vision and Pattern Recognition · Computer Science 2025-06-09 Luka Vetoshkin , Dmitry Yudin

Current methods for 3D semantic segmentation propose training models with limited annotations to address the difficulty of annotating large, irregular, and unordered 3D point cloud data. They usually focus on the 3D domain only, without…

Computer Vision and Pattern Recognition · Computer Science 2025-08-28 Lechun You , Zhonghua Wu , Weide Liu , Xulei Yang , Jun Cheng , Wei Zhou , Bharadwaj Veeravalli , Guosheng Lin