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This paper conducts research on the established model and presents the main conclusions . Firstly, by separately considering the infectivity of each of the two infectious diseases and the infectivity of the population simultaneously…

Populations and Evolution · Quantitative Biology 2025-03-13 Yang Liu

In this work we have investigated the evolutionary dynamics of a generalist pathogen, e.g. a virus population, that evolves towards specialisation in an environment with multiple host types. We have particularly explored under which…

Dynamical Systems · Mathematics 2020-06-24 Anel Nurtay , Matthew G. Hennessy , Lluís Alsedà , Santiago F. Elena , Josep Sardanyés

A probabilistic approach to the epidemic evolution on realistic social-contact networks allows for characteristic differences among subjects, including the individual number and structure of social contacts, and the heterogeneity of the…

Social and Information Networks · Computer Science 2022-02-11 Jan B. Broekaert , Davide La Torre , Faizal Hafiz

This paper considers a susceptible-infected-susceptible (SIS) epidemic reaction-diffusion model with no-flux boundary conditions and varying total population. The interaction of the susceptible and infected people is describe by the…

Analysis of PDEs · Mathematics 2024-12-13 Rui Peng , Rachidi B. Salako , Yixiang Wu

For many infectious diseases, a small-world network on an underlying regular lattice is a suitable simplified model for the contact structure of the host population. It is well known that the contact network, described in this setting by a…

Populations and Evolution · Quantitative Biology 2009-11-11 M. M. Telo da Gama , A. Nunes

Motivated by observations in sequence data of herpesviruses, we introduce a multi-locus model for the joint evolution of different genotypes in a virus population that is distributed across a population of hosts. In the model, virus…

Populations and Evolution · Quantitative Biology 2025-09-24 Raphael Eichhorn , Cornelia Pokalyuk

We introduce a kinetic framework for modeling the time evolution of the statistical distributions of the population densities in the three compartments of susceptible, infectious, and recovered individuals, under epidemic spreading driven…

Analysis of PDEs · Mathematics 2025-12-16 Giorgio Martalò , Giuseppe Toscani , Mattia Zanella

In many epidemiological and ecological contexts, there is a trade-off between infections and interactions. This arises because the links between individuals capable of spreading infections are also often associated with beneficial…

Physics and Society · Physics 2025-04-04 Bunlang Thatchai , Christopher E. Overton , Thomas House

Network ecology is a rising field of quantitative biology representing ecosystems as complex networks. A suitable example is parasite spreading: several parasites may be transmitted among their hosts through different mechanisms, each one…

Quantitative Methods · Quantitative Biology 2016-09-12 Massimo Stella , Cecilia S. Andreazzi , Sanja Selakovic , Alireza Goudarzi , Alberto Antonioni

The spread of infectious diseases, rumors, fashions, innovations are complex contagion processes, embedded both in networked and spatial contexts. Here we investigate the pattern dynamics of a complex contagion, where two agents, say $A$…

Physics and Society · Physics 2019-02-18 Li Chen

Despite the availability of effective vaccines, the persistence of SARS-CoV-2 suggests that co-circulation with other pathogens and resulting multi-epidemics may become increasingly frequent. To better forecast and control the risk of such…

We develop a multiple compartment Susceptible-Infected-Recovered (SIR) model to analyze the spread of several infectious diseases through different geographic areas. Additionally, we propose a data-quality sensitive optimization framework…

Populations and Evolution · Quantitative Biology 2019-06-21 Inbar Seroussi , Nir Levy , Daniela Paolotti , Nir Sochen , Elad Yom-Tov

In this work, we aim to understand the influence of the heterogeneity of infection rates on the Susceptible-Infected-Susceptible (SIS) epidemic spreading. Employing the classic SIS model as the benchmark, we study the influence of the…

Physics and Society · Physics 2016-04-06 Bo Qu , Huijuan Wang

We develop a theory for the susceptible-infected-susceptible (SIS) epidemic model on networks that incorporate both network structure and dynamic correlations. This theory can account for the multistage onset of the epidemic phase in…

Physics and Society · Physics 2021-04-07 Chao-Ran Cai , Zhi-Xi Wu , Petter Holme

We consider an epidemiological model that includes waning and boosting of immunity. Assuming that repeated exposure to the pathogen fully restores immunity, we derive an SIRS-type model with discrete and distributed delays. First we prove…

Dynamical Systems · Mathematics 2016-06-14 Maria Vittoria Barbarossa , Monika Polner , Gergely Röst

We introduce a two-strain model with asymmetric temporary immunity periods and partial cross-immunity. We derive explicit conditions for competitive exclusion and coexistence of the strains depending on the strain-specific basic…

Dynamical Systems · Mathematics 2023-06-28 Matthew D. Johnston , Bruce Pell , David A. Rubel

Mathematical models of infectious disease transmission typically neglect within-host dynamics. Yet within-host dynamics - including pathogen replication, host immune responses, and interactions with microbiota - are crucial not only for…

Populations and Evolution · Quantitative Biology 2023-12-20 Cameron A. Smith , Ben Ashby

Understanding the spatio-temporal evolution of epidemics with multiple pathogens requires not only new theoretical models but also careful analysis of their practical consequences. Building on the Multiplex Bi-Virus Reaction-Diffusion…

Physics and Society · Physics 2025-09-04 Alyssa Yu , Laura P. Schaposnik

This paper examines a susceptible-infected-susceptible (SIS) epidemic reaction-diffusion model with no-flux boundary conditions and constant total population. The infection mechanism in the model is described by a nonlinear term of the form…

Analysis of PDEs · Mathematics 2024-12-20 Rui Peng , Rachidi B Salako , Yixiang Wu

The vertebrate adaptive immune system provides a flexible and diverse set of molecules to neutralize pathogens. Yet, viruses such as HIV can cause chronic infections by evolving as quickly as the adaptive immune system, forming an…

Populations and Evolution · Quantitative Biology 2016-06-22 Armita Nourmohammad , Jakub Otwinowski , Joshua B. Plotkin