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Currently, the field of structure-based drug design is dominated by three main types of algorithms: search-based algorithms, deep generative models, and reinforcement learning. While existing works have typically focused on comparing models…

Machine Learning · Computer Science 2024-06-06 Kangyu Zheng , Yingzhou Lu , Zaixi Zhang , Zhongwei Wan , Yao Ma , Marinka Zitnik , Tianfan Fu

Translating statistical methods into reliable software is a persistent bottleneck in quantitative research. Existing AI code-generation tools produce code quickly but cannot guarantee faithful implementation -- a critical requirement for…

Software Engineering · Computer Science 2026-04-07 Tianzhu Qin , Yiqing Xu

Formal program specifications play a crucial role in various stages of software development. However, manually crafting formal program specifications is rather difficult, making the job time-consuming and labor-intensive. It is even more…

Software Engineering · Computer Science 2025-02-26 Lezhi Ma , Shangqing Liu , Yi Li , Xiaofei Xie , Lei Bu

AI coding assistants and autonomous agents are becoming integral to software development workflows, reshaping how code is produced, reviewed, and maintained. While recent research has focused mainly on the capabilities and impacts of…

Software Engineering · Computer Science 2026-05-07 Christoph Treude

Efficiently representing source code is crucial for various software engineering tasks such as code classification and clone detection. Existing approaches primarily use Abstract Syntax Tree (AST), and only a few focus on semantic graphs…

Software Engineering · Computer Science 2023-12-27 Karthik Chandra Swarna , Noble Saji Mathews , Dheeraj Vagavolu , Sridhar Chimalakonda

Large language models (LLMs) are increasingly used to generate requirements specifications, design documents, code, and test cases. In contrast, much less attention has been given to a more difficult assurance problem: statically verifying…

Software Engineering · Computer Science 2026-05-19 Zhi Quan Zhou , Dave Towey , Tsong Yueh Chen

Satisfactory software performance is essential for the adoption and the success of a product. In organizations that follow traditional software development models (e.g., waterfall), Software Performance Engineering (SPE) involves…

Software Engineering · Computer Science 2022-05-09 Gunnar Kudrjavets , Jeff Thomas , Nachiappan Nagappan

Large Language Models (LLMs) are revolutionizing Software Engineering (SE) by introducing innovative methods for tasks such as collecting requirements, designing software, generating code, and creating test cases, among others. This article…

Software Engineering · Computer Science 2024-05-06 Malik Abdul Sami , Zeeshan Rasheed , Muhammad Waseem , Zheying Zhang , Tomas Herda , Pekka Abrahamsson

With the advent of generative LLMs and their advanced code generation capabilities, some people already envision the end of traditional software engineering, as LLMs may be able to produce high-quality code based solely on the requirements…

Software Engineering · Computer Science 2025-07-11 Jonathan Ullrich , Matthias Koch , Andreas Vogelsang

Generative AI is reshaping product design practices through "vibe coding," where product team members express intent in natural language and AI translates it into functional prototypes and code. Despite rapid adoption, little research has…

Human-Computer Interaction · Computer Science 2026-05-04 Jie Li , Youyang Hou , Laura Lin , Ruihao Zhu , Hancheng Cao , Abdallah El Ali

The rise of AI-driven coding assistants signals a fundamental shift in how software is built. While AI coding assistants have been integrated into existing Integrated Development Environments (IDEs), their full potential remains largely…

Software Engineering · Computer Science 2025-03-05 Raula Gaikovina Kula , Christoph Treude

Recent regulations, such as the European General Data Protection Regulation (GDPR), put stringent constraints on the handling of personal data. Privacy, like security, is a non-functional property, yet most software design tools are focused…

Software Engineering · Computer Science 2020-11-25 Hanaa Alshareef , Sandro Stucki , Gerardo Schneider

Machine Learning software documentation is different from most of the documentations that were studied in software engineering research. Often, the users of these documentations are not software experts. The increasing interest in using…

Software Engineering · Computer Science 2020-02-03 Yalda Hashemi , Maleknaz Nayebi , Giuliano Antoniol

File systems are critical OS components that require constant evolution to support new hardware and emerging application needs. However, the traditional paradigm of developing features, fixing bugs, and maintaining the system incurs…

Operating Systems · Computer Science 2026-02-11 Qingyuan Liu , Mo Zou , Hengbin Zhang , Dong Du , Yubin Xia , Haibo Chen

Background: Studies on developer productivity and well-being find that the perceptions of productivity in a software team can be a socio-technical problem. Intuitively, problems and challenges can be better handled by managing expectations…

Software Engineering · Computer Science 2021-07-21 Khalid Hasan , Partho Chakraborty , Rifat Shahriyar , Anindya Iqbal , Gias Uddin

Speculative decoding (SD) accelerates large language model inference by employing a faster draft model for generating multiple tokens, which are then verified in parallel by the larger target model, resulting in the text generated according…

When engineering complex and distributed software and hardware systems (increasingly used in many sectors, such as manufacturing, aerospace, transportation, communication, energy, and health-care), quality has become a big issue, since…

Software Engineering · Computer Science 2009-10-06 Antonio Bucchiarone , Davide Di Ruscio , Henry Muccini , Patrizio Pelliccione

The emergence of Agentic AI is fundamentally transforming how software is designed, developed, and maintained. Traditional software development methodologies such as Agile, Kanban, ShapeUp, etc, were originally designed for human-centric…

Domain-driven design (DDD) is a powerful design technique for architecting complex software systems. This paper introduces a prompting framework that automates core DDD activities through structured large language model (LLM) interactions.…

Software Engineering · Computer Science 2026-03-30 Tobias Eisenreich , Husein Jusic , Stefan Wagner

Test and verification are essential activities in hardware and system design, but their complexity grows significantly with increasing system sizes. While Behavior Driven Development (BDD) has proven effective in software engineering, it is…

Software Engineering · Computer Science 2025-12-24 Rolf Drechsler , Qian Liu