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Epilepsy is the fourth most common neurological disorder, affecting about 1% of the population at all ages. As many as 60% of people with epilepsy experience focal seizures which originate in a certain brain area and are limited to part of…

Machine Learning · Computer Science 2019-03-20 Diyuan Lu , Jochen Triesch

Epilepsy is the second most common brain disorder after migraine. Automatic detection of epileptic seizures can considerably improve the patients' quality of life. Current Electroencephalogram (EEG)-based seizure detection systems encounter…

Signal Processing · Electrical Eng. & Systems 2018-03-28 Ramy Hussein , Hamid Palangi , Rabab Ward , Z. Jane Wang

Epilepsy is a dynamic and complex neurological disease affecting about 1% of the worldwide population, among which 30% of the patients are drug-resistant. Epilepsy is characterized by recurrent episodes of paroxysmal neural discharges (the…

Neurons and Cognition · Quantitative Biology 2021-01-27 Elif Köksal Ersöz , Julien Modolo , Fabrice Bartolomei , Fabrice Wendling

The Schr\"odinger bridge problem (SBP) finds the most likely stochastic evolution between two probability distributions given a prior stochastic evolution. As well as applications in the natural sciences, problems of this kind have…

Machine Learning · Statistics 2022-05-31 Francisco Vargas , Pierre Thodoroff , Neil D. Lawrence , Austen Lamacraft

We propose a novel Coupled Hidden Markov Model to detect epileptic seizures in multichannel electroencephalography (EEG) data. Our model defines a network of seizure propagation paths to capture both the temporal and spatial evolution of…

Signal Processing · Electrical Eng. & Systems 2018-08-13 Jeff Craley , Emily Johnson , Archana Venkataraman

Tipping points (TP) are abrupt transitions between metastable states in complex systems, most often described by a bifurcation or crisis of a multistable system induced by a slowly changing control parameter. An avenue for predicting TPs in…

Chaotic Dynamics · Physics 2025-11-07 Johannes Lohmann , Georg A. Gottwald

Simulating trajectories of multi-particle systems on complex energy landscapes is a central task in molecular dynamics (MD) and drug discovery, but remains challenging at scale due to computationally expensive and long simulations. Previous…

Machine Learning · Computer Science 2025-11-11 Sophia Tang , Yinuo Zhang , Pranam Chatterjee

We propose score dynamics (SD), a general framework for learning accelerated evolution operators with large timesteps from molecular-dynamics simulations. SD is centered around scores, or derivatives of the transition log-probability with…

Computational Physics · Physics 2024-03-08 Tim Hsu , Babak Sadigh , Vasily Bulatov , Fei Zhou

Epilepsy which is characterized by seizures is studied using EEG signals by recording the electrical activity of the brain. Different types of communication between different parts of the brain are characterized by many state of the art…

Machine Learning · Computer Science 2020-09-29 Mohammad Mansour , Fouad Khnaisser , Hmayag Partamian

The prediction of epileptic seizure has always been extremely challenging in medical domain. However, as the development of computer technology, the application of machine learning introduced new ideas for seizure forecasting. Applying…

Machine Learning · Computer Science 2019-10-08 Haotian Liu , Lin Xi , Ying Zhao , Zhixiang Li

This paper aims to conduct a comprehensive theoretical analysis of current diffusion models. We introduce a novel generative learning methodology utilizing the Schr{\"o}dinger bridge diffusion model in latent space as the framework for…

Machine Learning · Statistics 2024-12-24 Yuling Jiao , Lican Kang , Huazhen Lin , Jin Liu , Heng Zuo

Forecasting epileptic seizures from multivariate EEG signals represents a critical challenge in healthcare time series prediction, requiring high sensitivity, low false alarm rates, and subject-specific adaptability. We present STAN, an…

Machine Learning · Computer Science 2026-03-04 Zan Li , Kyongmin Yeo , Wesley Gifford , Lara Marcuse , Madeline Fields , Bülent Yener

Seizures are one of the defining symptoms in patients with epilepsy, and due to their unannounced occurrence, they can pose a severe risk for the individual that suffers it. New research efforts are showing a promising future for the…

Machine Learning · Computer Science 2021-08-09 Carlos H. Mendoza-Cardenas , Austin J. Brockmeier

An end-to-end platform assembling multiple tiers is built for precisely cognizing brain activities. Being fed massive electroencephalogram (EEG) data, the time-frequency spectrograms are conventionally projected into the episode-wise…

Signal Processing · Electrical Eng. & Systems 2022-04-22 Zheng Chen , Lingwei Zhu , Ziwei Yang , Renyuan Zhang

Epilepsy is a prevalent neurological disorder marked by sudden, brief episodes of excessive neuronal activity caused by abnormal electrical discharges, which may lead to some mental disorders. Most existing deep learning methods for…

Machine Learning · Computer Science 2025-10-16 Zexin Wang , Lin Shi , Haoyu Wu , Junru Luo , Xiangzeng Kong , Jun Qi

Changes in the statistical properties of a stochastic process are typically assumed to occur via change-points, which demark instantaneous moments of complete and total change in process behavior. In cases where these transitions occur…

Machine Learning · Statistics 2022-05-06 Chris Browne

Electroencephalography (EEG) provides a non-invasive insight into the brain's cognitive and emotional dynamics. However, modeling how these states evolve in real time and quantifying the energy required for such transitions remains a major…

Machine Learning · Computer Science 2026-04-03 Sriram Sattiraju , Vaibhav Gollapalli , Aryan Shah , Timothy McMahan

Epilepsy is a disease in which frequent seizures occur due to abnormal activity of neurons. Patients affected by this disease can be treated with the help of medicines or surgical procedures. However, both of these methods are not quite…

Neurons and Cognition · Quantitative Biology 2020-04-20 Syed Muhammad Usman , Shahzad Latif , Arshad Beg

Epilepsy is a common neurological disorder characterized by recurrent seizures accompanied by excessive synchronous brain activity. The process of structural and functional brain alterations leading to increased seizure susceptibility and…

Signal Processing · Electrical Eng. & Systems 2020-06-18 Diyuan Lu , Sebastian Bauer , Valentin Neubert , Lara Sophie Costard , Felix Rosenow , Jochen Triesch

Schizophrenia is a complex psychiatric disorder involving changes in thought patterns, perception, mood, and behavior. The diagnosis of schizophrenia is challenging and requires that patients show two or more positive symptoms for at least…

Machine Learning · Computer Science 2021-02-17 Maritza Tynes , Mahboobeh Parsapoor