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There is growing interest in anticipating critical transitions in natural systems, often pursued through statistical detection of early warning signals associated with dynamical bifurcations. In stochastic dynamical systems, such signals…

Dynamical Systems · Mathematics 2026-03-30 Florian Suerhoff , Andreas Morr , Sebastian Bathiany , Niklas Boers , Christian Kuehn

Epilepsy is a chronic, noncommunicable brain disorder, and sudden seizure onsets can significantly impact patients' quality of life and health. However, wearable seizure-predicting devices are still limited, partly due to the bulky size of…

Signal Processing · Electrical Eng. & Systems 2025-07-22 Ruifeng Zheng , Cong Chen , Shuang Wang , Yiming Liu , Lin You , Jindong Lu , Ruizhe Zhu , Guodao Zhang , Kejie Huang

Accurate prediction of epileptic seizures has remained elusive, despite the many advances in machine learning and time-series classification. In this work, we develop a convolutional network module that exploits Electroencephalogram (EEG)…

Image and Video Processing · Electrical Eng. & Systems 2020-07-24 Ramy Hussein , Soojin Lee , Rabab Ward , Martin J. McKeown

As the prevalence of Alzheimer's disease (AD) rises, improving mechanistic insight from non-invasive biomarkers is increasingly critical. Recent work suggests that circuit-level brain alterations manifest as changes in…

Neural and Evolutionary Computing · Computer Science 2026-02-10 Szymon Mamoń , Max Talanov , Alessandro Crimi

Bifurcations can cause dynamical systems with slowly varying parameters to transition to far-away attractors. The terms ``critical transition'' or ``tipping point'' have been used to describe this situation. Critical transitions have been…

Dynamical Systems · Mathematics 2015-03-17 Christian Kuehn

Over the past decade, high-frequency oscillations (HFOs) have been studied as a promising biomarker for localizing epileptogenic areas in drug-resistant patients requiring pre-surgical intervention, while exploiting intracranial…

Signal Processing · Electrical Eng. & Systems 2024-12-24 Zayneb Sadek , Abir Hadriche , Rahma Maalej , Nawel Jmail

Epileptic seizures are one of the most well-known dysfunctions of the nervous system. During a seizure, a highly synchronized behavior of neural activity is observed that can cause symptoms ranging from mild sensual malfunctions to the…

Neurons and Cognition · Quantitative Biology 2011-08-01 Christian Kuehn , Christian Meisel

Epileptic seizure detection from EEG signals remains challenging due to the high dimensionality and nonlinear, potentially stochastic, dynamics of neural activity. In this work, we investigate whether features derived from topological data…

Machine Learning · Computer Science 2026-04-15 Sunia Tanweer , Narayan Puthanmadam Subramaniyam , Firas A. Khasawneh

In recent years, machine learning has become an increasingly powerful tool for supporting seizure detection and monitoring in epilepsy care. Traditional approaches focus on identifying seizures only after they begin, which limits the…

Machine Learning · Computer Science 2025-10-30 Ria Jayanti , Tanish Jain

In this work, we study early-warning signs for stochastic partial differential equations (SPDEs), where the linearization around a steady state has continuous spectrum. The studied warning sign takes the form of qualitative changes in the…

Probability · Mathematics 2023-07-27 Paolo Bernuzzi , Antonia Düx , Christian Kühn

Seizure prediction has attracted a growing attention as one of the most challenging predictive data analysis efforts in order to improve the life of patients living with drug-resistant epilepsy and tonic seizures. Many outstanding works…

Computer Vision and Pattern Recognition · Computer Science 2017-12-07 Nhan Duy Truong , Anh Duy Nguyen , Levin Kuhlmann , Mohammad Reza Bonyadi , Jiawei Yang , Omid Kavehei

An accurate seizure prediction system enables early warnings before seizure onset of epileptic patients. It is extremely important for drug-refractory patients. Conventional seizure prediction works usually rely on features extracted from…

Signal Processing · Electrical Eng. & Systems 2021-08-18 Yankun Xu , Jie Yang , Shiqi Zhao , Hemmings Wu , Mohamad Sawan

Epilepsy is one of the most common neurological disorders, affecting about 1% of the population at all ages. Detecting the development of epilepsy, i.e., epileptogenesis (EPG), before any seizures occur could allow for early interventions…

Machine Learning · Computer Science 2020-06-18 Diyuan Lu , Sebastian Bauer , Valentin Neubert , Lara Sophie Costard , Felix Rosenow , Jochen Triesch

Accurate prediction of epileptic seizures could prove critical for improving patient safety and quality of life in drug-resistant epilepsy. Although deep learning-based approaches have shown promising seizure prediction performance using…

Signal Processing · Electrical Eng. & Systems 2024-12-31 Petros Koutsouvelis , Bartlomiej Chybowski , Alfredo Gonzalez-Sulser , Shima Abdullateef , Javier Escudero

Extracting governing stochastic differential equation models from elusive data is crucial to understand and forecast dynamics for complex systems. We devise a method to extract the drift term and estimate the diffusion coefficient of a…

Numerical Analysis · Mathematics 2020-08-21 Jian Ren , Jinqiao Duan

The early prediction of tipping points, distinguished by sudden and catastrophic shifts from stable states, poses a challenging task that would enable us to assess the impending threat across natural and engineered systems. This threat…

Statistical Mechanics · Physics 2025-12-02 Tapas Bar , Anurag Banerjee , Blai Casals , Gustau Catalan , Javier Rodríguez-Viejo

Epileptic seizures are transient neurological events characterized by abnormal and excessive neuron activity in the brain, which are often associated with measurable disturbances in the cardiovascular system. Traditionally,…

Signal Processing · Electrical Eng. & Systems 2026-05-20 Mohammad Reza Chopannavaz , Foad Ghaderi

Neural oscillations are considered to be brain-specific signatures of information processing and communication in the brain. They also reflect pathological brain activity in neurological disorders, thus offering a basis for diagnoses and…

Neurons and Cognition · Quantitative Biology 2023-10-23 Tena Dubcek , Debora Ledergerber , Jana Thomann , Giovanna Aiello , Marc Serra-Garcia , Lukas Imbach , Rafael Polania

Current early warning signs for tipping points often fail to distinguish between catastrophic shifts and less dramatic state changes, such as spatial pattern formation. This paper introduces a novel method that addresses this limitation by…

Dynamical Systems · Mathematics 2025-10-03 Paul A. Sanders , Robbin Bastiaansen

The ability to reliably predict critical transitions in dynamical systems is a long-standing goal of diverse scientific communities. Previous work focused on early warning signals related to local bifurcations (critical slowing down) and…

Adaptation and Self-Organizing Systems · Physics 2017-11-15 Rajat Karnatak , Holger Kantz , Stephan Bialonski