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Accurate polyp segmentation remains challenging due to irregular lesion morphologies, ambiguous boundaries, and heterogeneous imaging conditions. While U-Net variants excel at local feature fusion, they often lack explicit mechanisms to…

Image and Video Processing · Electrical Eng. & Systems 2025-02-27 Pu Wang , Huaizhi Ma , Zhihua Zhang , Zhuoran Zheng

The biological functions of proteins often depend on dynamic structural ensembles. In this work, we develop a flow-based generative modeling approach for learning and sampling the conformational landscapes of proteins. We repurpose highly…

Biomolecules · Quantitative Biology 2024-09-04 Bowen Jing , Bonnie Berger , Tommi Jaakkola

The occlusion problem remains a crucial challenge in optical flow estimation (OFE). Despite the recent significant progress brought about by deep learning, most existing deep learning OFE methods still struggle to handle occlusions; in…

Computer Vision and Pattern Recognition · Computer Science 2024-03-05 Bo Wang , Yifan Zhang , Jian Li , Yang Yu , Zhenping Sun , Li Liu , Dewen Hu

Structure-based drug design (SBDD) aims to efficiently discover high-affinity ligands within vast chemical spaces. However, current generative models struggle with objective misalignment and rigid sampling budgets. We present MolFORM, a…

Computational Engineering, Finance, and Science · Computer Science 2026-02-26 Daiheng Zhang , Zhao Zhang

Standard flow matching scales well but typically relies on an unstructured source distribution, limiting its ability to learn interpretable latent structure. Latent-variable models, by contrast, capture structure but often sacrifice…

Machine Learning · Computer Science 2026-05-11 Xavier Sumba , Carles Balsells-Rodas , Yingzhen Li

Deep generative models that produce novel molecular structures have the potential to facilitate chemical discovery. Flow matching is a recently proposed generative modeling framework that has achieved impressive performance on a variety of…

Machine Learning · Computer Science 2024-11-26 Ian Dunn , David R. Koes

Diffusion models have achieved significant progress in both image and video generation while still suffering from huge computation costs. As an effective solution, flow matching aims to reflow the diffusion process of diffusion models into…

Graphics · Computer Science 2025-03-13 Lei Ke , Haohang Xu , Xuefei Ning , Yu Li , Jiajun Li , Haoling Li , Yuxuan Lin , Dongsheng Jiang , Yujiu Yang , Linfeng Zhang

Flow Matching is a powerful framework for learning transport maps between probability distributions. Yet its standard single-parameter formulation is not designed to capture multi-parameter variations where the resulting transport should be…

Learning-based optical flow estimation has been dominated with the pipeline of cost volume with convolutions for flow regression, which is inherently limited to local correlations and thus is hard to address the long-standing challenge of…

Computer Vision and Pattern Recognition · Computer Science 2022-07-19 Haofei Xu , Jing Zhang , Jianfei Cai , Hamid Rezatofighi , Dacheng Tao

Binaural rendering aims to synthesize binaural audio that mimics natural hearing based on a mono audio and the locations of the speaker and listener. Although many methods have been proposed to solve this problem, they struggle with…

We develop an interpolation-based framework for noisy linear systems with unknown system matrix with bounded norm (implying bounded growth or non-increasing energy), and bounded process noise energy. The proposed approach characterizes all…

Systems and Control · Electrical Eng. & Systems 2025-11-17 Martina Vanelli , Nima Monshizadeh , Julien M. Hendrickx

Conditional flow matching (CFM) stands out as an efficient, simulation-free approach for training flow-based generative models, achieving remarkable performance for data generation. However, CFM is insufficient to ensure accuracy in…

Machine Learning · Computer Science 2026-02-03 Yuhao Huang , Taos Transue , Shih-Hsin Wang , William Feldman , Hong Zhang , Bao Wang

We develop a \emph{flow-matching framework} for transporting probability measures under control-affine dynamics and for steering systems to points or target sets. Starting from the continuity equation associated with the control affine…

Optimization and Control · Mathematics 2026-05-06 Karthik Elamvazhuthi

Modeling continuous-time dynamics from sparse and irregularly-sampled time series remains a fundamental challenge. Neural controlled differential equations provide a principled framework for such tasks, yet their performance is highly…

Machine Learning · Computer Science 2026-04-03 YongKyung Oh , Dong-Young Lim , Sungil Kim

Intra-device parallelism addresses resource under-utilization in ML inference and training by overlapping the execution of operators with different resource usage. However, its wide adoption is hindered by a fundamental conflict with the…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-05-22 Yi Pan , Yile Gu , Jinbin Luo , Yibo Wu , Ziren Wang , Hongtao Zhang , Ziyi Xu , Shengkai Lin , Baris Kasikci , Stephanie Wang

Traditional discriminative computer vision relies predominantly on static projections, mapping input features to outputs in a single computational step. Although efficient, this paradigm lacks the iterative refinement and robustness…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Om Govind Jha , Manoj Bamniya , Ayon Borthakur

Interfacial fluctuations in a two-phase binary fluid mixture reveal signatures of underlying physical processes that occur within each phase and on a range of spatial and temporal scales. In this study, we investigate a model binary fluid…

Fluid Dynamics · Physics 2026-03-04 Samuel Z Khiangte , Triparna Sanyal , Sumantra Sarkar , Nairita Pal

Accurate and efficient fluid flow models are essential for applications relating to many physical phenomena including geophysical, aerodynamic, and biological systems. While these flows may exhibit rich and multiscale dynamics, in many…

Fluid Dynamics · Physics 2024-08-27 Benjamin D. Shaffer , Jeremy R. Vorenberg , M. Ani Hsieh

Spline interpolation is a widely used class of methods for solving interpolation problems by constructing smooth interpolants that minimize a regularized energy functional involving the Laplacian operator. While many existing approaches…

Computation · Statistics 2026-03-30 Charlie Sire , Mike Pereira , Thomas Romary

We learn to compute optical flow by combining a classical spatial-pyramid formulation with deep learning. This estimates large motions in a coarse-to-fine approach by warping one image of a pair at each pyramid level by the current flow…

Computer Vision and Pattern Recognition · Computer Science 2016-11-22 Anurag Ranjan , Michael J. Black
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