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In this work a Lattice Boltzmann Immersed Boundary method is used for predicting the dynamics of rigid and deformable adhesive micro carriers (1 um) navigating a capillary by the size of 10 um with 20% hematocrit. Red cells and particles…

Soft Condensed Matter · Physics 2020-08-31 Alessandro Coclite

The aim of this paper is to propose a new numerical model to simulate 2D vesicles interacting with a newtonian fluid. The inextensible membrane is modeled by a chain of circular rigid particles which are maintained in cohesion by using two…

Mathematical Physics · Physics 2012-02-15 Mourad Ismail , Aline Lefebvre-Lepot

The present work reports the formation and the characterization of antipleptic and symplectic metachronal waves in 3D cilia arrays immersed in a two-fluid environment, with a viscosity ratio of 20. A coupled…

Biological Physics · Physics 2017-08-02 Sylvain Chateau , Julien Favier , Umberto D 'Ortona , Sébastien Poncet

Dynamic organization of the cytoskeletal filaments and rod-like proteins in the cell membrane and other biological interfaces occurs in many cellular processes. Previous modeling studies have considered the dynamics of a single rod on fluid…

Fluid Dynamics · Physics 2022-06-17 Wenzheng Shi , Moslem Moradi , Ehssan Nazockdast

Cilia and flagella are actively bending slender organelles, performing functions such as motility, feeding and embryonic symmetry breaking. We review the mechanics of viscous-dominated microscale flow, including time-reversal symmetry, drag…

Quantitative Methods · Quantitative Biology 2013-09-06 Thomas D. Montenegro-Johnson , Andrew A. Smith , David J. Smith , Daniel Loghin , John R. Blake

The movement of subaqueous sediment in laminar shearing flow is numerically investigated by the coupled lattice Boltzmann and discrete element methods. First, the numerical method is validated by comparing the phase diagram proposed by…

Fluid Dynamics · Physics 2022-06-09 Duo Wang

In this work we study the effect of metachronal waves on the flow created by magnetically-driven plate-like artificial cilia in microchannels using numerical simulations. The simulations are performed using a coupled magneto-mechanical…

Fluid Dynamics · Physics 2015-05-30 Syed Khaderi , Jaap den Toonder , Patrick Onck

Coordinated cilia are used throughout the natural world for micronscale fluid transport. They are often modelled with regular filament arrays on fixed, planar surfaces. Here, we simulate hundreds of interacting active filaments on spherical…

Fluid Dynamics · Physics 2021-12-01 Timothy A Westwood , Eric E Keaveny

We investigate the trajectories of rigid fibers as they are transported in a pressure-driven flow, at low Reynolds number, in shallow Hele Shaw cells. The transverse confinement and the resulting viscous friction on these elongated objects,…

Non-equilibrium processes which convert chemical energy into mechanical motion enable the motility of organisms. Bundles of inextensible filaments driven by energy transduction of molecular motors form essential components of micron-scale…

Soft Condensed Matter · Physics 2013-06-13 Abhrajit Laskar , Rajeev Singh , Somdeb Ghose , Gayathri Jayaraman , P. B. Sunil Kumar , R. Adhikari

Cellular membranes are elastic lipid bilayers that contain a variety of proteins, including ion channels, receptors, and scaffolding proteins. These proteins are known to diffuse in the plane of the membrane and to influence the bending of…

Soft Condensed Matter · Physics 2020-10-28 Arijit Mahapatra , David Saintillan , Padmini Rangamani

We study the time evolution and driven motion of thin liquid films lying on top of chemical patterns on a substrate. Lattice-Boltzmann and molecular dynamics methods are used for simulations of the flow of microscopic and nanoscopic films,…

Soft Condensed Matter · Physics 2012-04-04 Fabian Dörfler , Markus Rauscher , Joel Koplik , Jens Harting , S. Dietrich

We study numerically how multiple deformable capsules squeeze into a constriction. This situation is largely encountered in microfluidic chips designed to manipulate living cells, which are soft entities. We use fully three-dimensional…

Soft Condensed Matter · Physics 2021-12-15 Clément Bielinski , Othmane Aouane , Jens Harting , Badr Kaoui

To mimic the mechanical response of passive biological cilia in complex fluids, we study the bending dynamics of an anchored elastic fiber submitted to a dilute granular suspension under shear. We show that the bending fluctuations of the…

A highly organized and densely packed lattice of molecular machinery within the sarcomeres of muscle cells powers contraction. Although many of the proteins that drive contraction have been studied extensively, the mechanical impact of…

Subcellular Processes · Quantitative Biology 2021-06-22 Sage A Malingen , Kaitlyn Hood , Eric Lauga , Anette Hosoi , Thomas L Daniel

Tiny cilia drive the flow of surrounding fluids through asymmetric jumping, which is one of the main ways for biological organisms to control fluid transport at the micro-scale. Due to its huge application prospects in medical and…

Optimization and Control · Mathematics 2024-01-08 Shuangshuang Yu , Zheng Ning , Ge Chen

In disordered porous media, two-phase flow of immiscible fluids (biphasic flow) is organized in patterns that sometimes exhibit fractal geometries over a range of length scales, depending on the capillary, gravitational and viscous forces…

Understanding the transport of particles immersed in a carrier fluid (bedload transport) is still an exciting challenge. Among the different types of gas-solid flows, when the dynamics of solid particles is essentially dominated by…

Statistical Mechanics · Physics 2023-07-28 Vicente Garzó

Motile cilia drive biological fluid transport through whip-like beating motions that synchronize into metachronal waves. The lengths of these cilia span three orders of magnitude, from microns in human airways to millimeters in ctenophores.…

Active semiflexible filaments are crucial in various biophysical processes, yet insights into their single-filament behavior have predominantly relied on theory and simulations, owing to the scarcity of controllable synthetic systems. Here,…

Soft Condensed Matter · Physics 2025-07-14 Bipul Biswas , Prasanna More , Hima Nagamanasa Kandula