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Large Language Models (LLMs) possess latent multi-token prediction (MTP) abilities despite being trained only for next-token generation. We introduce ESP (Embedding-Space Probing), a simple and training-free MTP method that probes an LLM…

Computation and Language · Computer Science 2026-05-29 Raghavv Goel , Mukul Gagrani , Mingu Lee , Chris Lott

The high incidence and mortality rates associated with respiratory diseases underscores the importance of early screening. Machine learning models can automate clinical consultations and auscultation, offering vital support in this area.…

Machine Learning · Computer Science 2024-10-10 Yuwei Zhang , Tong Xia , Aaqib Saeed , Cecilia Mascolo

Deep Learning based models are currently dominating most state-of-the-art solutions for disease prediction. Existing works employ RNNs along with multiple levels of attention mechanisms to provide interpretability. These deep learning…

Machine Learning · Statistics 2022-06-01 Subhadip Maji , Raghav Bali , Sree Harsha Ankem , Kishore V Ayyadevara

Objective: Today's neural machine translation (NMT) can achieve near human-level translation quality and greatly facilitates international communications, but the lack of parallel corpora poses a key problem to the development of…

Computation and Language · Computer Science 2022-02-08 Shengxuan Luo , Huaiyuan Ying , Jiao Li , Sheng Yu

Patient-trial matching requires reasoning over long, heterogeneous electronic health records (EHRs) and complex eligibility criteria, posing significant challenges for scalability, generalization, and computational efficiency. Existing…

Computation and Language · Computer Science 2026-04-27 Xiaodi Li , Yang Xiao , Munhwan Lee , Konstantinos Leventakos , Young J. Juhn , David Jones , Terence T. Sio , Wei Liu , Maria Vassilaki , Nansu Zong

Foundation models trained on electronic health records show strong performance on many clinical prediction tasks but are limited by sparse and irregular documentation. Wearable devices provide dense continuous physiological signals but lack…

Machine Learning · Computer Science 2026-01-21 Yuanyun Zhang , Han Zhou , Li Feng , Yilin Hong , Shi Li

This study reviewed the use of Large Language Models (LLMs) in healthcare, focusing on their training corpora, customization techniques, and evaluation metrics. A systematic search of studies from 2021 to 2024 identified 61 articles. Four…

Computation and Language · Computer Science 2025-02-18 Shuqi Yang , Mingrui Jing , Shuai Wang , Jiaxin Kou , Manfei Shi , Weijie Xing , Yan Hu , Zheng Zhu

Standardized patients (SPs) are indispensable for clinical skills training but remain expensive and difficult to scale. Although large language model (LLM)-based virtual standardized patients (VSPs) have been proposed as an alternative,…

Computation and Language · Computer Science 2026-03-24 Bingquan Zhang , Xiaoxiao Liu , Yuchi Wang , Lei Zhou , Qianqian Xie , Benyou Wang

While Transformer language models (LMs) are state-of-the-art for information extraction, long text introduces computational challenges requiring suboptimal preprocessing steps or alternative model architectures. Sparse attention LMs can…

Computation and Language · Computer Science 2022-12-01 Joel Stremmel , Brian L. Hill , Jeffrey Hertzberg , Jaime Murillo , Llewelyn Allotey , Eran Halperin

Large language models (LLMs) can capture rich representations of concepts that are useful for real-world tasks. However, language alone is limited. While existing LLMs excel at text-based inferences, health applications require that models…

Computation and Language · Computer Science 2023-05-26 Xin Liu , Daniel McDuff , Geza Kovacs , Isaac Galatzer-Levy , Jacob Sunshine , Jiening Zhan , Ming-Zher Poh , Shun Liao , Paolo Di Achille , Shwetak Patel

The introduction of Large Language Models (LLMs), and the vast volume of publicly available medical data, amplified the application of NLP to the medical domain. However, LLMs are pretrained on data that are not explicitly relevant to the…

Computation and Language · Computer Science 2023-12-12 Chris Solomou

Large Language Models (LLMs) have demonstrated remarkable efficacy in text embedding, yet current adaptation methods like LoRA face significant bottlenecks in computational efficiency and cross-architecture transferability. Whenever a new…

Computation and Language · Computer Science 2026-05-28 Yu-Che Tsai , Kuan-Yu Chen , Yuan-Hao Chen , Yu-Han Chang , Ching-Yu Tsai , Yu-Hsiang Chuang , Shou-De Lin

Word embeddings are a powerful approach for analyzing language and have been widely popular in numerous tasks in information retrieval and text mining. Training embeddings over huge corpora is computationally expensive because the input is…

Machine Learning · Computer Science 2018-12-11 Avishek Anand , Megha Khosla , Jaspreet Singh , Jan-Hendrik Zab , Zijian Zhang

Recent years have seen particular interest in using electronic medical records (EMRs) for secondary purposes to enhance the quality and safety of healthcare delivery. EMRs tend to contain large amounts of valuable clinical notes. Learning…

Computation and Language · Computer Science 2022-07-25 Hoda Memarzadeh , Nasser Ghadiri , Maryam Lotfi Shahreza

Electronic health records (EHRs) are rich clinical data sources but complex repositories of patient data, spanning structured elements (demographics, vitals, lab results, codes), unstructured clinical notes and other modalities of data.…

Artificial Intelligence · Computer Science 2025-08-25 Sonish Sivarajkumar , Hang Zhang , Yuelyu Ji , Maneesh Bilalpur , Xizhi Wu , Chenyu Li , Min Gu Kwak , Shyam Visweswaran , Yanshan Wang

Clinical trials are essential for drug development but often suffer from expensive, inaccurate and insufficient patient recruitment. The core problem of patient-trial matching is to find qualified patients for a trial, where patient…

Artificial Intelligence · Computer Science 2021-04-13 Xingyao Zhang , Cao Xiao , Lucas M. Glass , Jimeng Sun

Agent-based simulation is crucial for modeling complex human behavior, yet traditional approaches require extensive domain knowledge and large datasets. In data-scarce healthcare settings where historic and counterfactual data are limited,…

Artificial Intelligence · Computer Science 2025-04-01 Sarah Martinson , Lingkai Kong , Cheol Woo Kim , Aparna Taneja , Milind Tambe

Cancer treatments are known to introduce cardiotoxicity, negatively impacting outcomes and survivorship. Identifying cancer patients at risk of heart failure (HF) is critical to improving cancer treatment outcomes and safety. This study…

Machine Learning · Computer Science 2024-11-05 Ziyi Chen , Mengyuan Zhang , Mustafa Mohammed Ahmed , Yi Guo , Thomas J. George , Jiang Bian , Yonghui Wu

Large language models (LLMs) have demonstrated strong performance on medical benchmarks, including question answering and diagnosis. To enable their use in clinical settings, LLMs are typically further adapted through continued pretraining…

How people narrate their experiences offers a window into how the mind organizes them. Computational approaches to therapeutic writing have evolved from lexical counting to neural methods, yet remain fragmented: dictionary tools miss…

Computation and Language · Computer Science 2026-05-01 Yuxi Ma , Jieming Cui , Muyang Li , Ye Zhao , Yu Li , Yixuan Wang , Chi Zhang , Yinyin Zang , Yixin Zhu