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Demographics, Social determinants of health, and family history documented in the unstructured text within the electronic health records are increasingly being studied to understand how this information can be utilized with the structured…

Computation and Language · Computer Science 2023-09-15 Neel Bhate , Ansh Mittal , Zhe He , Xiao Luo

Large pre-trained language models (LMs) have been widely adopted in biomedical and clinical domains, introducing many powerful LMs such as bio-lm and BioELECTRA. However, the applicability of these methods to real clinical use cases is…

Computation and Language · Computer Science 2022-11-16 Samuel Cahyawijaya , Bryan Wilie , Holy Lovenia , Huan Zhong , MingQian Zhong , Yuk-Yu Nancy Ip , Pascale Fung

The extraction of critical patient information from Electronic Health Records (EHRs) poses significant challenges due to the complexity and unstructured nature of the data. Traditional machine learning approaches often fail to capture…

Computation and Language · Computer Science 2025-09-03 Zhimeng Luo , Abhibha Gupta , Adam Frisch , Daqing He

The rapid accumulation of Electronic Health Records (EHRs) has transformed healthcare by providing valuable data that enhance clinical predictions and diagnoses. While conventional machine learning models have proven effective, they often…

Objective: Large language models (LLMs) are attracting increasing interest in healthcare. This commentary evaluates the potential of LLMs to improve clinical prediction models (CPMs) for diagnostic and prognostic tasks, with a focus on…

Computers and Society · Computer Science 2025-11-07 Yusuf Yildiz , Goran Nenadic , Meghna Jani , David A. Jenkins

Tutoring is an effective instructional method for enhancing student learning, yet its success relies on the skill and experience of the tutors. This reliance presents challenges for the widespread implementation of tutoring, particularly in…

Human-Computer Interaction · Computer Science 2025-10-21 Chentianye Xu , Jionghao Lin , Tongshuang Wu , Vincent Aleven , Kenneth R. Koedinger

Accurate diagnosis of Alzheimer's disease (AD) requires handling tabular biomarker data, yet such data are often small and incomplete, where deep learning models frequently fail to outperform classical methods. Pretrained large language…

Computation and Language · Computer Science 2026-03-19 Sophie Kearney , Shu Yang , Zixuan Wen , Weimin Lyu , Bojian Hou , Duy Duong-Tran , Tianlong Chen , Jason H. Moore , Marylyn D. Ritchie , Chao Chen , Li Shen

We consider the hierarchical representation of documents as graphs and use geometric deep learning to classify them into different categories. While graph neural networks can efficiently handle the variable structure of hierarchical…

Computation and Language · Computer Science 2021-11-01 Sohrab Ferdowsi , Nikolay Borissov , Julien Knafou , Poorya Amini , Douglas Teodoro

Clinical notes are an efficient way to record patient information but are notoriously hard to decipher for non-experts. Automatically simplifying medical text can empower patients with valuable information about their health, while saving…

Since annotating medical images for segmentation tasks commonly incurs expensive costs, it is highly desirable to design an annotation-efficient method to alleviate the annotation burden. Recently, contrastive learning has exhibited a great…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Yixuan Wu , Jintai Chen , Jiahuan Yan , Yiheng Zhu , Danny Z. Chen , Jian Wu

Supervised learning is limited both by the quantity and quality of the labeled data. In the field of medical record tagging, writing styles between hospitals vary drastically. The knowledge learned from one hospital might not transfer well…

Computation and Language · Computer Science 2018-11-30 Yuhui Zhang , Allen Nie , James Zou

Pre-training has shown success in different areas of machine learning, such as Computer Vision (CV), Natural Language Processing (NLP) and medical imaging. However, it has not been fully explored for clinical data analysis. Even though an…

Machine Learning · Computer Science 2022-06-10 Chantal Pellegrini , Anees Kazi , Nassir Navab

Clinical language models are important for many applications in healthcare, but their development depends on access to extensive clinical text for pretraining. However, obtaining clinical notes from electronic health records (EHRs) at scale…

Computation and Language · Computer Science 2024-12-02 Jinghui Liu , Anthony Nguyen

Clinical diagnosis, which aims to assign diagnosis codes for a patient based on the clinical note, plays an essential role in clinical decision-making. Considering that manual diagnosis could be error-prone and time-consuming, many…

Computation and Language · Computer Science 2021-01-28 Yichao Du , Pengfei Luo , Xudong Hong , Tong Xu , Zhe Zhang , Chao Ren , Yi Zheng , Enhong Chen

High-throughput phenotyping, the automated mapping of patient signs and symptoms to standardized ontology concepts, is essential to gaining value from electronic health records (EHR) in the support of precision medicine. Despite…

Artificial Intelligence · Computer Science 2024-06-24 Syed I. Munzir , Daniel B. Hier , Chelsea Oommen , Michael D. Carrithers

Developing high-performance entity normalization algorithms that can alleviate the term variation problem is of great interest to the biomedical community. Although deep learning-based methods have been successfully applied to biomedical…

Information Retrieval · Computer Science 2019-08-12 Zongcheng Ji , Qiang Wei , Hua Xu

The integration of multimodal Electronic Health Records (EHR) data has significantly improved clinical predictive capabilities. Leveraging clinical notes and multivariate time-series EHR, existing models often lack the medical context…

Artificial Intelligence · Computer Science 2024-02-13 Yinghao Zhu , Changyu Ren , Shiyun Xie , Shukai Liu , Hangyuan Ji , Zixiang Wang , Tao Sun , Long He , Zhoujun Li , Xi Zhu , Chengwei Pan

Electronic Health Records (EHR) are high-dimensional data with implicit connections among thousands of medical concepts. These connections, for instance, the co-occurrence of diseases and lab-disease correlations can be informative when…

Machine Learning · Computer Science 2021-03-29 Weicheng Zhu , Narges Razavian

Labeling data is essential for training text classifiers but is often difficult to accomplish accurately, especially for complex and abstract concepts. Seeking an improved method, this paper employs a novel approach using a generative…

Computation and Language · Computer Science 2024-12-31 Sergio Pelaez , Gaurav Verma , Barbara Ribeiro , Philip Shapira

Electronic Health Records (EHRs) and routine documentation practices play a vital role in patients' daily care, providing a holistic record of health, diagnoses, and treatment. However, complex and verbose EHR narratives overload healthcare…

Computation and Language · Computer Science 2025-02-26 Yanjun Gao , Ruizhe Li , Emma Croxford , John Caskey , Brian W Patterson , Matthew Churpek , Timothy Miller , Dmitriy Dligach , Majid Afshar