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Text-conditioned molecular generation aims to translate natural-language descriptions into chemical structures, enabling scientists to specify functional groups, scaffolds, and physicochemical constraints without handcrafted rules.…

Machine Learning · Computer Science 2025-11-18 Lingxiao Li , Haobo Zhang , Bin Chen , Jiayu Zhou

Generative models have the potential to accelerate key steps in the discovery of novel molecular therapeutics and materials. Diffusion models have recently emerged as a powerful approach, excelling at unconditional sample generation and,…

Biomolecules · Quantitative Biology 2024-07-17 Leo Klarner , Tim G. J. Rudner , Garrett M. Morris , Charlotte M. Deane , Yee Whye Teh

Autoregressive models for text sometimes generate repetitive and low-quality output because errors accumulate during the steps of generation. This issue is often attributed to exposure bias - the difference between how a model is trained,…

Computation and Language · Computer Science 2024-03-26 Yizhe Zhang , Jiatao Gu , Zhuofeng Wu , Shuangfei Zhai , Josh Susskind , Navdeep Jaitly

Diffusion models excel at capturing the natural design spaces of images, molecules, DNA, RNA, and protein sequences. However, rather than merely generating designs that are natural, we often aim to optimize downstream reward functions while…

Recent advances in diffusion models have revolutionized video generation, offering superior temporal consistency and visual quality compared to traditional generative adversarial networks-based approaches. While this emerging field shows…

Computer Vision and Pattern Recognition · Computer Science 2026-02-11 Yimu Wang , Xuye Liu , Wei Pang , Li Ma , Shuai Yuan , Paul Debevec , Ning Yu

Diffusion models generate images with an unprecedented level of quality, but how can we freely rearrange image layouts? Recent works generate controllable scenes via learning spatially disentangled latent codes, but these methods do not…

Computer Vision and Pattern Recognition · Computer Science 2024-04-11 Jiawei Ren , Mengmeng Xu , Jui-Chieh Wu , Ziwei Liu , Tao Xiang , Antoine Toisoul

Multiscale spatial structure complicates temporal prediction because small-scale spatial fluctuations influence large-scale evolution, yet resolving all scales is often intractable. Standard diffusion models do not address this problem…

Fluid Dynamics · Physics 2026-04-02 Yuki Yasuda , Tobias Bischoff

The rapid development of generative diffusion models has significantly advanced the field of style transfer. However, most current style transfer methods based on diffusion models typically involve a slow iterative optimization process,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Feihong He , Gang Li , Fuhui Sun , Mengyuan Zhang , Lingyu Si , Xiaoyan Wang , Li Shen

Diffusion models have transformed image synthesis through iterative denoising, by defining trajectories from noise to coherent data. While their capabilities are widely celebrated, a critical challenge remains unaddressed: ensuring…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Andreas Floros , Seyed-Mohsen Moosavi-Dezfooli , Pier Luigi Dragotti

This paper introduces a diffusion-based planner for leader--follower formation control in cluttered environments. The diffusion policy is used to generate the trajectory of the midpoint of two leaders as a rigid bar in the plane, thereby…

Robotics · Computer Science 2026-01-19 Hieu Do Quang , Chien Truong-Quoc , Quoc Van Tran

Diffusion model has demonstrated remarkable capability in video generation, which further sparks interest in introducing trajectory control into the generation process. While existing works mainly focus on training-based methods (e.g.,…

Computer Vision and Pattern Recognition · Computer Science 2024-06-25 Haonan Qiu , Zhaoxi Chen , Zhouxia Wang , Yingqing He , Menghan Xia , Ziwei Liu

Portrait animation aims to generate photo-realistic videos from a single source image by reenacting the expression and pose from a driving video. While early methods relied on 3D morphable models or feature warping techniques, they often…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Mallikarjun B. R. , Fei Yin , Vikram Voleti , Nikita Drobyshev , Maksim Lapin , Aaryaman Vasishta , Varun Jampani

We introduce a learning-guided motion planning framework that generates seed trajectories using a diffusion model for trajectory optimization. Given a workspace, our method approximates the configuration space (C-space) obstacles through an…

Robotics · Computer Science 2025-03-20 Mingyo Seo , Yoonyoung Cho , Yoonchang Sung , Peter Stone , Yuke Zhu , Beomjoon Kim

The field of neural rendering has witnessed significant progress with advancements in generative models and differentiable rendering techniques. Though 2D diffusion has achieved success, a unified 3D diffusion pipeline remains unsettled.…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Yushi Lan , Fangzhou Hong , Shangchen Zhou , Shuai Yang , Xuyi Meng , Yongwei Chen , Zhaoyang Lyu , Bo Dai , Xingang Pan , Chen Change Loy

Urban mobility data has significant connections with economic growth and plays an essential role in various smart-city applications. However, due to privacy concerns and substantial data collection costs, fine-grained human mobility…

Social and Information Networks · Computer Science 2025-07-21 Baoshen Guo , Zhiqing Hong , Junyi Li , Shenhao Wang , Jinhua Zhao

We introduce a framework for joint grounded scene graph - image generation, a challenging task involving high-dimensional, multi-modal structured data. To effectively model this complex joint distribution, we adopt a factorized approach:…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Bicheng Xu , Qi Yan , Renjie Liao , Lele Wang , Leonid Sigal

Pervasive integration of GPS-enabled devices and data acquisition technologies has led to an exponential increase in GPS trajectory data, fostering advancements in spatial-temporal data mining research. Nonetheless, GPS trajectories contain…

Machine Learning · Computer Science 2023-10-25 Yuanshao Zhu , Yongchao Ye , Shiyao Zhang , Xiangyu Zhao , James J. Q. Yu

Graph is a prevalent discrete data structure, whose generation has wide applications such as drug discovery and circuit design. Diffusion generative models, as an emerging research focus, have been applied to graph generation tasks.…

Machine Learning · Computer Science 2024-11-05 Zhe Xu , Ruizhong Qiu , Yuzhong Chen , Huiyuan Chen , Xiran Fan , Menghai Pan , Zhichen Zeng , Mahashweta Das , Hanghang Tong

Diffusion-based methods can generate realistic images and videos, but they struggle to edit existing objects in a video while preserving their appearance over time. This prevents diffusion models from being applied to natural video editing…

Computer Vision and Pattern Recognition · Computer Science 2023-08-21 Wenhao Chai , Xun Guo , Gaoang Wang , Yan Lu

Text-to-image diffusion models have demonstrated a remarkable ability to generate photorealistic images from natural language prompts. These high-resolution, language-guided synthesized images are essential for the explainability of disease…

Computer Vision and Pattern Recognition · Computer Science 2025-04-01 Zahra TehraniNasab , Amar Kumar , Tal Arbel
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