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Reliable detection of the prodromal stages of Alzheimer's disease (AD) remains difficult even today because, unlike other neurocognitive impairments, there is no definitive diagnosis of AD in vivo. In this context, existing research has…

Machine Learning · Computer Science 2021-08-03 Amish Mittal , Sourav Sahoo , Arnhav Datar , Juned Kadiwala , Hrithwik Shalu , Jimson Mathew

Subjective cognitive decline (SCD) is a preclinical stage of Alzheimer's disease (AD) which occurs even before mild cognitive impairment (MCI). Progressive SCD will convert to MCI with the potential of further evolving to AD. Therefore,…

Computer Vision and Pattern Recognition · Computer Science 2023-02-17 Hao Guan , Ling Yue , Pew-Thian Yap , Shifu Xiao , Andrea Bozoki , Mingxia Liu

Medical vision-language models (Med-VLMs) have shown impressive results in tasks such as report generation and visual question answering, but they still face several limitations. Most notably, they underutilize patient metadata and lack…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Fangqi Cheng , Surajit Ray , Xiaochen Yang

Automated feature extraction from MRI brain scans and diagnosis of Alzheimer's disease are ongoing challenges. With advances in 3D imaging technology, 3D data acquisition is becoming more viable and efficient than its 2D counterpart. Rather…

Image and Video Processing · Electrical Eng. & Systems 2024-03-19 Fatemeh Ahmadi , Mohamad Ebrahim Shiri , Behroz Bidabad , Maral Sedaghat , Pooran Memari

Alzheimer's disease (AD) is characterized by progressive neurodegeneration and results in detrimental structural changes in human brains. Detecting these changes is crucial for early diagnosis and timely intervention of disease progression.…

Image and Video Processing · Electrical Eng. & Systems 2024-11-25 Yasmine Mustafa , Mohamed Elmahallawy , Tie Luo

Increasing effort in brain image analysis has been dedicated to early diagnosis of Alzheimer's disease (AD) based on neuroimaging data. Most existing studies have been focusing on binary classification problems, e.g., distinguishing AD…

Computer Vision and Pattern Recognition · Computer Science 2017-09-14 Hongming Li , Mohamad Habes , Yong Fan

Quantitative magnetic resonance imaging (qMRI) offers tissue-specific physical parameters with significant potential for neuroscience research and clinical practice. However, lengthy scan times for 3D multiparametric qMRI acquisition limit…

Computer Vision and Pattern Recognition · Computer Science 2024-10-03 Guoyan Lao , Ruimin Feng , Haikun Qi , Zhenfeng Lv , Qiangqiang Liu , Chunlei Liu , Yuyao Zhang , Hongjiang Wei

Defaults in vascular (VN) and neuronal networks of spinal cord are responsible for serious neurodegenerative pathologies. Because of inadequate investigation tools, the lacking knowledge of the complete fine structure of VN and neuronal…

Structural magnetic resonance imaging (sMRI) provides accurate estimates of the brain's structural organization and learning invariant brain representations from sMRI is an enduring issue in neuroscience. Previous deep representation…

Computer Vision and Pattern Recognition · Computer Science 2023-06-21 Ning Jiang , Gongshu Wang , Tianyi Yan

Transfer learning has remarkably improved computer vision. These advances also promise improvements in neuroimaging, where training set sizes are often small. However, various difficulties arise in directly applying models pretrained on…

Image and Video Processing · Electrical Eng. & Systems 2023-03-03 Umang Gupta , Tamoghna Chattopadhyay , Nikhil Dhinagar , Paul M. Thompson , Greg Ver Steeg , The Alzheimer's Disease Neuroimaging Initiative

Current methods for searching brain MR images rely on text-based approaches, highlighting a significant need for content-based image retrieval (CBIR) systems. Directly applying 3D brain MR images to machine learning models offers the…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Shuhei Tomoshige , Hayato Muraki , Kenichi Oishi , Hitoshi Iyatomi

Medical image segmentation, a crucial task in computer vision, facilitates the automated delineation of anatomical structures and pathologies, supporting clinicians in diagnosis, treatment planning, and disease monitoring. Notably,…

Computer Vision and Pattern Recognition · Computer Science 2024-12-11 Fuchen Zheng , Xinyi Chen , Xuhang Chen , Haolun Li , Xiaojiao Guo , Weihuang Liu , Chi-Man Pun , Shoujun Zhou

Magnetic resonance imaging (MRI) provides detailed soft-tissue characteristics that assist in disease diagnosis and screening. However, the accuracy of clinical practice is often hindered by missing or unusable slices due to various…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Junkai Liu , Nay Aung , Theodoros N. Arvanitis , Stefan K. Piechnik , Joao A C Lima , Steffen E. Petersen , Le Zhang

Multimodal medical image fusion plays an instrumental role in several areas of medical image processing, particularly in disease recognition and tumor detection. Traditional fusion methods tend to process each modality independently before…

Image and Video Processing · Electrical Eng. & Systems 2023-10-11 Lin Liu , Xinxin Fan , Chulong Zhang , Jingjing Dai , Yaoqin Xie , Xiaokun Liang

To address the problem of medical image recognition, computer vision techniques like convolutional neural networks (CNN) are frequently used. Recently, 3D CNN-based models dominate the field of magnetic resonance image (MRI) analytics. Due…

Computer Vision and Pattern Recognition · Computer Science 2023-02-27 Yuxuan Zhang , Qingzhong Wang , Jiang Bian , Yi Liu , Yanwu Xu , Dejing Dou , Haoyi Xiong

To analyze the abundance of multidimensional data, tensor-based frameworks have been developed. Traditionally, the matrix singular value decomposition (SVD) is used to extract the most dominant features from a matrix containing the…

Machine Learning · Computer Science 2021-11-02 Katherine Keegan , Tanvi Vishwanath , Yihua Xu

Magnetic resonance (MR) images collected in 2D clinical protocols typically have large inter-slice spacing, resulting in high in-plane resolution and reduced through-plane resolution. Super-resolution technique can enhance the through-plane…

Image and Video Processing · Electrical Eng. & Systems 2023-03-21 Xin Wang , Sheng Wang , Honglin Xiong , Kai Xuan , Zixu Zhuang , Mengjun Liu , Zhenrong Shen , Xiangyu Zhao , Lichi Zhang , Qian Wang

Conventional MRI reconstruction methods treat images and coil sensitivities as discrete objects, leading to high memory demands and limited structural awareness that hamper effective regularization. These limitations hinder accurate…

Image and Video Processing · Electrical Eng. & Systems 2026-05-12 Ray Sheombarsing , Max van Riel , David Heesterbeek , Nico van den Berg , Alessandro Sbrizzi

Structural MRI and PET imaging play an important role in the diagnosis of Alzheimer's disease (AD), showing the morphological changes and glucose metabolism changes in the brain respectively. The manifestations in the brain image of some…

Image and Video Processing · Electrical Eng. & Systems 2023-08-11 Yanteng Zhang , Qizhi Teng , Xiaohai He , Tong Niu , Lipei Zhang , Yan Liu , Chao Ren

Multi-contrast Magnetic Resonance Imaging super-resolution (MC-MRI SR) aims to enhance low-resolution (LR) contrasts leveraging high-resolution (HR) references, shortening acquisition time and improving imaging efficiency while preserving…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Xiaoman Wu , Lubin Gan , Siying Wu , Jing Zhang , Yunwei Ou , Xiaoyan Sun