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Objectives We aimed to evaluate the diagnostic performance of deep learning (DL)-based radiomics models for the noninvasive prediction of isocitrate dehydrogenase (IDH) mutation and 1p/19q co-deletion status in glioma patients using MRI…

Quantitative Methods · Quantitative Biology 2025-08-19 Somayeh Farahani , Marjaneh Hejazi , Mehnaz Tabassum , Antonio Di Ieva , Neda Mahdavifar , Sidong Liu

Variational autoencoder (VAE) and generative adversarial networks (GAN) have found widespread applications in clustering and have achieved significant success. However, the potential of these approaches may be limited due to VAE's mediocre…

Machine Learning · Computer Science 2023-12-14 Jie Yan , Jing Liu , Zhong-yuan Zhang

This work develops a novel set of algorithms, alternating Gradient Descent (GD) and minimization for MRI (altGDmin-MRI1 and altGDmin-MRI2), for accelerated dynamic MRI by assuming an approximate low-rank (LR) model on the matrix formed by…

Image and Video Processing · Electrical Eng. & Systems 2024-11-13 Silpa Babu , Sajan Goud Lingala , Namrata Vaswani

Liver cancer is a leading cause of cancer-related mortality worldwide, with its high genetic heterogeneity complicating diagnosis and treatment. This study introduces DLSOM, a deep learning framework utilizing stacked autoencoders to…

Genomics · Quantitative Biology 2024-12-18 Fabio Zamio

The parsimonious Gaussian mixture models, which exploit an eigenvalue decomposition of the group covariance matrices of the Gaussian mixture, have shown their success in particular in cluster analysis. Their estimation is in general…

Machine Learning · Statistics 2018-10-18 Faicel Chamroukhi , Marius Bartcus , Hervé Glotin

Block Diffusion Models (BDMs) support parallel generation, flexible-length output, and KV caching, making them promising for efficient document parsing. However, existing BDMs bind denoising and cache commitment to fixed block boundaries:…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Mingxu Chai , Ziyu Shen , Chenyu Liu , Kaidi Zhang , Jiazheng Zhang , Dingwei Zhu , Zhiheng Xi , Ruoyu Chen , Jun Long , Jihua Kang , Tao Gui , Qi Zhang

In the genomic era, the identification of gene signatures associated with disease is of significant interest. Such signatures are often used to predict clinical outcomes in new patients and aid clinical decision-making. However, recent…

Methodology · Statistics 2019-03-27 Naim U. Rashid , Quefeng Li , Jen Jen Yeh , Joseph G. Ibrahim

Diffusion language models (DLMs) have recently emerged as a promising alternative to autoregressive (AR) approaches, enabling parallel token generation beyond a rigid left-to-right order. Despite growing empirical success, the theoretical…

Machine Learning · Computer Science 2026-02-24 Yunxiao Zhao , Changxiao Cai

Large language models (LLMs) have demonstrated remarkable capabilities across various tasks. However, their widespread application is hindered by the resource-intensive decoding process. To address this challenge, current approaches have…

Computation and Language · Computer Science 2024-04-19 Ziqian Zeng , Jiahong Yu , Qianshi Pang , Zihao Wang , Huiping Zhuang , Hongen Shao , Xiaofeng Zou

Clustering is a widely deployed unsupervised learning tool. Model-based clustering is a flexible framework to tackle data heterogeneity when the clusters have different shapes. Likelihood-based inference for mixture distributions often…

Machine Learning · Statistics 2023-05-30 Yubo Zhuang , Xiaohui Chen , Yun Yang

Protein inverse folding is a fundamental problem in bioinformatics, aiming to recover the amino acid sequences from a given protein backbone structure. Despite the success of existing methods, they struggle to fully capture the intricate…

Machine Learning · Computer Science 2024-12-13 Chenglin Wang , Yucheng Zhou , Zijie Zhai , Jianbing Shen , Kai Zhang

The rapidly emerging field of computational pathology has the potential to enable objective diagnosis, therapeutic response prediction and identification of new morphological features of clinical relevance. However, deep learning-based…

Image and Video Processing · Electrical Eng. & Systems 2020-05-25 Ming Y. Lu , Drew F. K. Williamson , Tiffany Y. Chen , Richard J. Chen , Matteo Barbieri , Faisal Mahmood

Two challenging problems in the clinical study of cancer are the characterization of cancer subtypes and the classification of individual patients according to those subtypes. Statistical approaches addressing these problems are hampered by…

Methodology · Statistics 2012-02-28 John A. Dawson , Christina Kendziorski

In this paper, we introduce Adaptive Cluster Lasso(ACL) method for variable selection in high dimensional sparse regression models with strongly correlated variables. To handle correlated variables, the concept of clustering or grouping…

Machine Learning · Statistics 2016-03-14 Niharika Gauraha , Swapan K. Parui

There is a rich literature on clustering functional data with applications to time-series modeling, trajectory data, and even spatio-temporal applications. However, existing methods routinely perform global clustering that enforces…

Methodology · Statistics 2024-12-16 Tsung-Hung Yao , Suprateek Kundu

Background: Accurate segmentation of diffuse large B-cell lymphoma (DLBCL) lesions is challenging due to their complex patterns in medical imaging. Objective: This study aims to develop a precise segmentation method for DLBCL using…

Image and Video Processing · Electrical Eng. & Systems 2024-09-10 Huan Huang , Liheng Qiu , Shenmiao Yang , Longxi Li , Jiaofen Nan , Yanting Li , Chuang Han , Fubao Zhu , Chen Zhao , Weihua Zhou

This paper features convolutional neural networks defined on hypercomplex algebras applied to classify lymphocytes in blood smear digital microscopic images. Such classification is helpful for the diagnosis of acute lymphoblast leukemia…

Computer Vision and Pattern Recognition · Computer Science 2024-01-05 Guilherme Vieira , Marcos Eduardo Valle

Context graphs are essential for modern AI applications including question answering, pattern discovery, and data analysis. Building accurate context graphs from structured databases requires inferring join relationships between entities.…

Databases · Computer Science 2026-03-05 Shivani Tripathi , Ravi Shetye , Shi Qiao , Alekh Jindal

Machine learning for tabular data remains constrained by poor schema generalization, a challenge rooted in the lack of semantic understanding of structured variables. This challenge is particularly acute in domains like clinical medicine,…

Machine Learning · Computer Science 2026-05-05 Hongxi Mao , Wei Zhou , Mengting Jia , Tao Fang , Huan Gao , Bin Zhang , Shangyang Li

Model-based clustering techniques have been widely applied to various application areas, while most studies focus on canonical mixtures with unique component distribution form. However, this strict assumption is often hard to satisfy. In…

Computer Vision and Pattern Recognition · Computer Science 2025-02-13 Fei Zheng , Nicolas Duchateau