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Related papers: AI-based Prediction of Biochemical Recurrence from…

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Accurate prediction of biochemical recurrence (BCR) after radical prostatectomy is critical for guiding adjuvant treatment and surveillance decisions in prostate cancer. However, existing clinicopathological risk models reduce complex…

Prostate cancer is one of the most frequently diagnosed malignancies in men worldwide. However, precise prediction of biochemical recurrence (BCR) after radical prostatectomy remains challenging due to the multifocality of tumors…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Yesung Cho , Dongmyung Shin , Sujeong Hong , Jooyeon Lee , Seongmin Park , Geongyu Lee , Jongbae Park , Hong Koo Ha

Almost 30% of prostate cancer (PCa) patients undergoing radical prostatectomy (RP) experience biochemical recurrence (BCR), characterized by increased prostate specific antigen (PSA) and associated with increased mortality. Accurate early…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Suhang You , Carla Pitarch-Abaigar , Sanket Kachole , Sumedh Sonawane , Juhyung Ha , Anish Sudarshan Gada , David Crandall , Rakesh Shiradkar , Spyridon Bakas

Time to biochemical recurrence in prostate cancer is essential for prognostic monitoring of the progression of patients after prostatectomy, which assesses the efficacy of the surgery. In this work, we proposed to leverage multiple instance…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Suhang You , Sanyukta Adap , Siddhesh Thakur , Bhakti Baheti , Spyridon Bakas

Accurate recurrence risk stratification is crucial for optimizing treatment plans for breast cancer patients. Current prognostic tools like Oncotype DX (ODX) offer valuable genomic insights for HR+/HER2- patients but are limited by cost and…

Image and Video Processing · Electrical Eng. & Systems 2024-09-25 Ziyu Su , Yongxin Guo , Robert Wesolowski , Gary Tozbikian , Nathaniel S. O'Connell , M. Khalid Khan Niazi , Metin N. Gurcan

In a dataset of 423 patients who had had radical prostatectomy for localised prostate cancer we estimated the apparent Shannon information (ASI) about time to biochemical recurrence in various subsets of the available pre-op variables using…

Applications · Statistics 2026-03-27 Tommy Walker Mackay , Mingtong Xu , Shahrokh F. Shariat , Roger Sewell

In oncology, recurrence after treatment is one of the major challenges, related to patients' survival and quality of life. Conventionally, prediction of cancer relapse has always relied on clinical observation with statistical model…

Machine Learning · Computer Science 2025-02-25 Muhammad Umer Qayyum , Muhammad Fahad , Nasrullah Abbasi

Prostate cancer diagnosis through MR imaging have currently relied on radiologists' interpretation, whilst modern AI-based methods have been developed to detect clinically significant cancers independent of radiologists. In this study, we…

Image and Video Processing · Electrical Eng. & Systems 2026-01-09 Xiangcen Wu , Yipei Wang , Qianye Yang , Natasha Thorley , Shonit Punwani , Veeru Kasivisvanathan , Ester Bonmati , Yipeng Hu

We investigate the connection between visual semantic features defined in PI-RADS and associated risk factors, moving beyond abnormal imaging findings, establishing a shared framework between medical and AI professionals by creating a…

In patients with biochemical recurrence of prostate cancer and negative PSMA PET/CT, radiomics features extracted from recurrence-prone organs can predict clinical progression and progression-free survival. In a cohort of 132 patients,…

Active surveillance (AS) is a suitable management option for newly-diagnosed prostate cancer (PCa), which usually presents low to intermediate clinical risk. Patients enrolled in AS have their tumor closely monitored via longitudinal…

Artificial Intelligence (AI) can potentially support histopathologists in the diagnosis of a broad spectrum of cancer types. In colorectal cancer (CRC), AI can alleviate the laborious task of characterization and reporting on resected…

Image and Video Processing · Electrical Eng. & Systems 2023-02-10 John-Melle Bokhorst , Iris D. Nagtegaal , Filippo Fraggetta , Simona Vatrano , Wilma Mesker , Michael Vieth , Jeroen van der Laak , Francesco Ciompi

Gleason grading of prostate cancer is an important prognostic factor but suffers from poor reproducibility, particularly among non-subspecialist pathologists. Although artificial intelligence (A.I.) tools have demonstrated Gleason grading…

Accurately predicting early recurrence in brain tumor patients following surgical resection remains a clinical challenge. This study proposes a multi-modal machine learning framework that integrates structural MRI features with clinical…

Machine Learning · Computer Science 2025-09-03 Cheng Cheng , Zeping Chen , Rui Xie , Peiyao Zheng , Xavier Wang

Accurate preoperative prediction of erectile dysfunction (ED) is important for counseling patients undergoing radical prostatectomy. While clinical features are established predictors, the added value of preoperative MRI remains…

Pre-biopsy magnetic resonance imaging (MRI) is increasingly used to target suspicious prostate lesions. This has led to artificial intelligence (AI) applications improving MRI-based detection of clinically significant prostate cancer…

Image and Video Processing · Electrical Eng. & Systems 2025-02-04 Hassan Jahanandish , Shengtian Sang , Cynthia Xinran Li , Sulaiman Vesal , Indrani Bhattacharya , Jeong Hoon Lee , Richard Fan , Geoffrey A. Sonna , Mirabela Rusu

Precision medicine has become a central focus in breast cancer management, advancing beyond conventional methods to deliver more precise and individualized therapies. Traditionally, histopathology images have been used primarily for…

Quantitative Methods · Quantitative Biology 2024-12-17 Suchithra Kunhoth , Somaya Al- Maadeed , Younes Akbari , Rafif Al Saady

Background: Transrectal ultrasound guided systematic biopsies of the prostate is a routine procedure to establish a prostate cancer diagnosis. However, the 10-12 prostate core biopsies only sample a relatively small volume of the prostate,…

Image and Video Processing · Electrical Eng. & Systems 2022-04-20 Bojing Liu , Yinxi Wang , Philippe Weitz , Johan Lindberg , Johan Hartman , Lars Egevad , Henrik Grönberg , Martin Eklund , Mattias Rantalainen

Brain metastases affect approximately between 20% and 40% of cancer patients and are commonly treated with radiotherapy or radiosurgery. Early prediction of recurrence following treatment could enable timely clinical intervention and…

Image and Video Processing · Electrical Eng. & Systems 2025-12-18 Ines Faria , Matheus Silva , Crystian Saraiva , Jose Soares , Victor Alves

Breast cancer is the most common malignancy affecting women worldwide and is notable for its morphologic and biologic diversity, with varying risks of recurrence following treatment. The Oncotype DX Breast Recurrence Score test is an…

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