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Related papers: MADE: Benchmark Environments for Closed-Loop Mater…

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Material scientists are increasingly adopting the use of machine learning (ML) for making potentially important decisions, such as, discovery, development, optimization, synthesis and characterization of materials. However, despite ML's…

Computational Physics · Physics 2019-03-12 Bhavya Kailkhura , Brian Gallagher , Sookyung Kim , Anna Hiszpanski , T. Yong-Jin Han

We present a novel computational paradigm for process design in manufacturing processes that incorporates simulation responses to optimize manufacturing process parameters in high-dimensional temporal and spatial design spaces. We developed…

Computational Engineering, Finance, and Science · Computer Science 2021-07-26 Mojtaba Mozaffar , Jian Cao

LLMs have made significant progress in complex but easy-to-verify problems, yet they still struggle with discovering the unknown. In this paper, we present \textbf{AlphaResearch}, an autonomous research agent designed to discover new…

Computation and Language · Computer Science 2026-04-02 Zhaojian Yu , Kaiyue Feng , Yilun Zhao , Shilin He , Xiao-Ping Zhang , Arman Cohan

Discovering materials that must simultaneously satisfy multiple competing constraints remains a central challenge in computational materials design, particularly in data-scarce regimes where conventional data-driven approaches are least…

Materials Science · Physics 2026-04-24 Qiulin Zeng , Tahiya Chowdhury , Md Shafayat Hossain

Earth system science is producing increasingly large, high-dimensional datasets from physics based Earth system models to AI-based weather and climate models. Embedding-based representations can make these data searchable through similarity…

Data Analysis, Statistics and Probability · Physics 2026-05-05 Nihanth W. Cherukuru , Matt Rehme , Kirsten J. Mayer , David John Gagne , John Schreck , John Clyne , Charlie Becker

It is important to develop sustainable processes in materials science and manufacturing that are environmentally friendly. AI can play a significant role in decision support here as evident from our earlier research leading to tools…

Artificial Intelligence · Computer Science 2023-03-27 Aparna S. Varde , Jianyu Liang

Large language models (LLMs) have enabled agentic AI systems for scientific discovery, but most approaches remain limited to textbased reasoning without automated experimental verification. We propose MIND, an LLM-driven framework for…

Multiagent Systems · Computer Science 2026-04-16 Geonhee Ahn , Donghyun Lee , Hayoung Doo , Jonggeol Na , Hyunsoo Cho , Sookyung Kim

The Discovery Engine is a general purpose automated system for scientific discovery, which combines machine learning with state-of-the-art ML interpretability to enable rapid and robust scientific insight across diverse datasets. In this…

Advances in generative artificial intelligence are transforming how metal-organic frameworks (MOFs) are designed and discovered. This Perspective introduces the shift from laborious enumeration of MOF candidates to generative approaches…

Machine learning has emerged as a transformative tool for solving differential equations (DEs), yet prevailing methodologies remain constrained by dual limitations: data-driven methods demand costly labeled datasets while model-driven…

Machine Learning · Computer Science 2026-01-01 Heng Wu , Benzhuo Lu

Retrieval-Augmented Generation (RAG) shows promise for enterprise knowledge work, yet it often underperforms in high-stakes decision settings that require deep synthesis, strict traceability, and recovery from underspecified prompts.…

Information Retrieval · Computer Science 2026-01-27 Xincheng You , Qi Sun , Neha Bora , Huayi Li , Shubham Goel , Kang Li , Sean Culatana

AI-powered autonomous experimentation (AI/AE) can accelerate materials discovery but its effectiveness for electronic materials is hindered by data scarcity from lengthy and complex design-fabricate-test-analyze cycles. Unlike experienced…

Combinatorial and guided screening of materials space with density-functional theory and related approaches has provided a wealth of hypothetical inorganic materials, which are increasingly tabulated in open databases. The OPTIMADE API is a…

The ability to automatically discover interpretable mathematical models from data could forever change how we model soft matter systems. For convex discovery problems with a unique global minimum, model discovery is well-established. It…

Soft Condensed Matter · Physics 2024-04-11 Kevin Linka , Ellen Kuhl

Drawing on ideas from continuous integration, we present concepts of an automated benchmarking pipeline for high performance applications. Customization and collaboration have been key design goals owing to the requirements of…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-05-28 Jan Vogelsang , Melissa Lober , Catherine Mia Schöfmann , José Villamar , Dennis Terhorst , Johanna Senk , Hans Ekkehard Plesser , Markus Diesmann , Susanne Kunkel , Anno C. Kurth

The discovery and design of new materials are paramount in the development of green technologies. High entropy oxides represent one such group that has only been tentatively explored, mainly due to the inherent problem of navigating vast…

Hyperparameter tuning of multi-stage pipelines introduces a significant computational burden. Motivated by the observation that work can be reused across pipelines if the intermediate computations are the same, we propose a pipeline-aware…

Machine Learning · Computer Science 2019-03-14 Liam Li , Evan Sparks , Kevin Jamieson , Ameet Talwalkar

Efficient screening of chemicals is essential for exploring new materials. However, the search space is astronomically large, making calculations with conventional computers infeasible. For example, an $N$-component system of organic…

Computational Physics · Physics 2021-01-13 Kan Hatakeyama-Sato , Takahiro Kashikawa , Koichi Kimura , Kenichi Oyaizu

Constraint Acquisition (CA) and related research on the validation and enhancement of Mathematical Programming (MP) models from domain knowledge artifacts are currently limited by inadequate benchmarks. This deficiency impedes…

Artificial Intelligence · Computer Science 2026-05-27 Rafał Stachowiak , Tomasz P. Pawlak