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Accurate quantification in positron emission tomography (PET) is essential for accurate diagnostic results and effective treatment tracking. A major issue encountered in PET imaging is attenuation. Attenuation refers to the diminution of…

Positron emission tomography (PET) is widely used in various clinical applications, including cancer diagnosis, heart disease and neuro disorders. The use of radioactive tracer in PET imaging raises concerns due to the risk of radiation…

Computer Vision and Pattern Recognition · Computer Science 2017-12-13 Junshen Xu , Enhao Gong , John Pauly , Greg Zaharchuk

PET is affected by statistical noise due to constraints on tracer dose and scan duration, impacting both diagnostic performance and quantitative accuracy. While deep learning (DL)-based PET denoising methods have been used to improve image…

As PET imaging is accompanied by substantial radiation exposure and cancer risk, reducing radiation dose in PET scans is an important topic. Recently, diffusion models have emerged as the new state-of-the-art generative model to generate…

Image and Video Processing · Electrical Eng. & Systems 2023-11-30 Huidong Xie , Weijie Gan , Bo Zhou , Xiongchao Chen , Qiong Liu , Xueqi Guo , Liang Guo , Hongyu An , Ulugbek S. Kamilov , Ge Wang , Chi Liu

This paper evaluates the performance of supervised and unsupervised deep learning models for denoising positron emission tomography (PET) images in the presence of reduced acquisition times. Our experiments consider 212 studies (56908…

Image and Video Processing · Electrical Eng. & Systems 2023-03-29 Ivan Kruzhilov , Stepan Kudin , Luka Vetoshkin , Elena Sokolova , Vladimir Kokh

Objective Positron emission tomography (PET) allows imaging of patho-physiological information as a form of rate constants from a dynamic image. The rate constant image(s) may be affected from noise on the dynamic image. We introduced an…

Medical Physics · Physics 2023-08-10 Nobuyuki Kudomi , Yukito Maeda

Image reconstruction from noisy sensor measurements is challenging and many methods have been proposed for it. Yet, most approaches focus on learning robust natural image priors while modeling the scene's noise statistics. In extremely…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Erez Yosef , Raja Giryes

Diffusion models have shown great promise in medical image denoising and reconstruction, but their application to Positron Emission Tomography (PET) imaging remains limited by tracer-specific contrast variability and high computational…

Image and Video Processing · Electrical Eng. & Systems 2026-02-03 Fumio Hashimoto , Kuang Gong

Dynamic positron emission tomography (PET) images can reveal the distribution of tracers in the organism and the dynamic processes involved in biochemical reactions, and it is widely used in clinical practice. Despite the high effectiveness…

Image and Video Processing · Electrical Eng. & Systems 2025-12-22 Jie Sun , Junyan Zhang , Qian Xia , Chuanfu Sun , Yumei Chen , Yunjie Yang , Huafeng Liu , Wentao Zhu , Qiegen Liu

PET imaging is an invaluable tool in clinical settings as it captures the functional activity of both healthy anatomy and cancerous lesions. Developing automatic lesion segmentation methods for PET images is crucial since manual lesion…

Image and Video Processing · Electrical Eng. & Systems 2024-11-05 Tanya Gatsak , Kumar Abhishek , Hanene Ben Yedder , Saeid Asgari Taghanaki , Ghassan Hamarneh

PET imaging is a powerful modality offering quantitative assessments of molecular and physiological processes. The necessity for PET denoising arises from the intrinsic high noise levels in PET imaging, which can significantly hinder the…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Siyeop Yoon , Rui Hu , Yuang Wang , Matthew Tivnan , Young-don Son , Dufan Wu , Xiang Li , Kyungsang Kim , Quanzheng Li

In contrast to non-medical image denoising, where enhancing image clarity is the primary goal, medical image denoising warrants preservation of crucial features without introduction of new artifacts. However, many denoising methods that…

Image and Video Processing · Electrical Eng. & Systems 2024-12-02 Md. Touhidul Islam , Md. Abtahi M. Chowdhury , Sumaiya Salekin , Aye T. Maung , Akil A. Taki , Hafiz Imtiaz

Positron Emission Tomography (PET) is a functional imaging modality that enables the visualization of biochemical and physiological processes across various tissues. Recently, deep learning (DL)-based methods have demonstrated significant…

Image and Video Processing · Electrical Eng. & Systems 2026-01-16 Yiran Sun , Osama Mawlawi

Score-based generative models have demonstrated highly promising results for medical image reconstruction tasks in magnetic resonance imaging or computed tomography. However, their application to Positron Emission Tomography (PET) is still…

Image and Video Processing · Electrical Eng. & Systems 2024-01-24 Imraj RD Singh , Alexander Denker , Riccardo Barbano , Željko Kereta , Bangti Jin , Kris Thielemans , Peter Maass , Simon Arridge

Image denoising is an important pre-processing step in medical image analysis. Different algorithms have been proposed in past three decades with varying denoising performances. More recently, having outperformed all conventional methods,…

Computer Vision and Pattern Recognition · Computer Science 2017-02-21 Lovedeep Gondara

Increasing use of CT in modern medical practice has raised concerns over associated radiation dose. Reduction of radiation dose associated with CT can increase noise and artifacts, which can adversely affect diagnostic confidence. Denoising…

Computer Vision and Pattern Recognition · Computer Science 2017-02-24 Qingsong Yang , Pingkun Yan , Mannudeep K. Kalra , Ge Wang

Dynamic positron emission tomography (dPET) is currently a widely used medical imaging technique for the clinical diagnosis, staging and therapy guidance of all kinds of human cancers. Higher temporal imaging resolution for the early stage…

Medical Physics · Physics 2021-12-07 Zixiang Chen , Yaping Wu , Na Zhang , Yu Shen , Hairong Zheng , Dong Liang , Meiyun Wang , Zhanli Hu

Positron Emission Tomography (PET) scanners are usually designed with the goal to obtain the best compromise between sensitivity, resolution, field-of-view size, and cost. Therefore, it is difficult to improve the resolution of a PET…

Medical Physics · Physics 2023-07-18 Pablo Galve , Alejandro Lopez-Montes , Jose M Udias , Stephen C Moore , Joaquin L Herraiz

Recent deep learning-based image denoising methods have shown impressive performance; however, many lack the flexibility to adjust the denoising strength based on the noise levels, camera settings, and user preferences. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2025-09-05 Youngjin Oh , Junhyeong Kwon , Keuntek Lee , Nam Ik Cho

Images from positron emission tomography (PET) provide metabolic information about the human body. They present, however, a spatial resolution that is limited by physical and instrumental factors often modeled by a blurring function. Since…

Computer Vision and Pattern Recognition · Computer Science 2016-08-08 Stéphanie Guérit , Adriana González , Anne Bol , John A. Lee , Laurent Jacques