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The main aim of the work is to present a general class of two time scales discrete-time epidemic models. In the proposed framework the disease dynamics is considered to act on a slower time scale than a second different process that could…

Dynamical Systems · Mathematics 2024-02-07 Luis Sanz-Lorenzo , Rafael Bravo de la Parra

We propose two SIR models which incorporate sociological behavior of groups of individuals. It is these differences in behaviors which impose different infection rates on the individual susceptible populations, rather than biological…

Dynamical Systems · Mathematics 2022-07-26 Robert F. Allen , Katherine Heller , Matthew A. Pons

The estimation from available data of parameters governing epidemics is a major challenge. In addition to usual issues (data often incomplete and noisy), epidemics of the same nature may be observed in several places or over different…

Methodology · Statistics 2021-09-20 Romain Narci , Maud Delattre , Catherine Larédo , Elisabeta Vergu

In this paper, we study the $SIS$ (susceptible-infected-susceptible) and $SIR$ (susceptible-infected-removed) epidemic models on undirected, weighted networks by deriving pairwise-type approximate models coupled with individual-based…

Dynamical Systems · Mathematics 2013-02-22 Prapanporn Rattana , Konstantin B. Blyuss , Ken T. D. Eames , Istvan Z. Kiss

Individual-based models of contagious processes are useful for predicting epidemic trajectories and informing intervention strategies. In such models, the incorporation of contact network information can capture the non-randomness and…

Populations and Evolution · Quantitative Biology 2023-11-09 Maxwell H. Wang , Jukka-Pekka Onnela

The coronavirus pandemic has rapidly evolved into an unprecedented crisis. The susceptible-infectious-removed (SIR) model and its variants have been used for modeling the pandemic. However, time-independent parameters in the classical…

Populations and Evolution · Quantitative Biology 2020-09-09 Hyokyoung G. Hong , Yi Li

National statistical institutes in many countries are now mandated to produce reliable statistics for important variables such as population, income, unemployment, health outcomes, etc. for small areas, defined by geography and/or…

Methodology · Statistics 2018-10-29 Adrijo Chakraborty , Gauri Sankar Datta , Abhyuday Mandal

We introduce a Bayesian sequential data assimilation method for COVID-19 forecasting. It is assumed that suitable transmission, epidemic and observation models are available and previously validated and the transmission and epidemic models…

Stochastic discrete-time SIS and SIR models of endemic diseases are introduced and analyzed. For the deterministic, mean-field model, the basic reproductive number $R_0$ determines their global dynamics. If $R_0\le 1$, then the frequency of…

Populations and Evolution · Quantitative Biology 2020-05-19 Sebastian J. Schreiber , Shuo Huang , Jifa Jiang , Hao Wang

Parameter estimates for associated genetic variants, report ed in the initial discovery samples, are often grossly inflated compared to the values observed in the follow-up replication samples. This type of bias is a consequence of the…

Applications · Statistics 2011-04-15 Lizhen Xu , Radu V. Craiu , Lei Sun

This paper introduces a sequential multiple importance sampling (SeMIS) algorithm for high-dimensional Bayesian inference. The method estimates Bayesian evidence using all generated samples from each proposal distribution while obtaining…

Methodology · Statistics 2025-07-08 Li Binbin , He Xiao , Liao Zihan

In causal inference, it is common to estimate the causal effect of a single treatment variable on an outcome. However, practitioners may also be interested in the effect of simultaneous interventions on multiple covariates of a fixed target…

Methodology · Statistics 2022-11-24 Jaime Roquero Gimenez , Dominik Rothenhäusler

For nearly a century, the initial reproduction number (R0) has been used as a one number summary to compare outbreaks of infectious disease, yet there is no `standard' estimator for R0. Difficulties in estimating R0 arise both from how a…

Populations and Evolution · Quantitative Biology 2020-03-25 Shannon Gallagher , Andersen Chang , William F. Eddy

Combining data has become an indispensable tool for managing the current diversity and abundance of data. But, as data complexity and data volume swell, the computational demands of previously proposed models for combining data escalate…

Methodology · Statistics 2024-06-13 Mario Figueira , David Conesa , Antonio López-Quílez , Iosu Paradinas

Bayesian statistics is an integral part of contemporary applied science. bayesics provides a single framework, unified in syntax and output, for performing the most commonly used statistical procedures, ranging from one- and two-sample…

Methodology · Statistics 2026-02-18 Daniel K. Sewell , Alan T. Arakkal

Estimation of epidemiological and population parameters from molecular sequence data has become central to the understanding of infectious disease dynamics. Various models have been proposed to infer details of the dynamics that describe…

Populations and Evolution · Quantitative Biology 2014-12-25 Alex Popinga , Tim Vaughan , Tanja Stadler , Alexei Drummond

Many quantities characterizing infectious disease outbreaks - like the effective reproduction number ($R_t$), defined as the average number of secondary infections a newly infected individual will cause over the course of their infection -…

Methodology · Statistics 2025-11-25 Jessalyn N. Sebastian , Volodymyr M. Minin

We introduce a new method to efficiently approximate the number of infections resulting from a given initially-infected node in a network of susceptible individuals. Our approach is based on counting the number of possible infection walks…

Biological Physics · Physics 2012-10-25 Frank Bauer , Joseph T. Lizier

The standard way to estimate the parameters $\Theta_\text{SEIR}$ (e.g., the transmission rate $\beta$) of an SEIR model is to use grid search, where simulations are performed on each set of parameters, and the parameter set leading to the…

Machine Learning · Statistics 2021-06-01 Chun Fan , Yuxian Meng , Xiaofei Sun , Fei Wu , Tianwei Zhang , Jiwei Li

The duration, type and structure of connections between individuals in real-world populations play a crucial role in how diseases invade and spread. Here, we incorporate the aforementioned heterogeneities into a model by considering a…

Physics and Society · Physics 2018-04-05 Rosanna C Barnard , Istvan Z Kiss , Luc Berthouze , Joel C Miller