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We study the inverse source problem in photoacoustic tomography (PAT) for mixed data, which denote a weighted linear combination of the acoustic pressure and its normal derivative on an observation surface. We consider in particular the…

Analysis of PDEs · Mathematics 2022-07-06 Florian Dreier , Markus Haltmeier

Polarimetric imaging, a technique that captures the invisible polarization-related properties of given materials, has broad applications from fundamental physics to advanced fields such as target recognition, stress detection, biomedical…

Quantitative photoacoustic tomography (QPAT) is a recent hybrid imaging modality that couples optical tomography with ultrasound imaging to achieve high resolution imaging of optical properties of scattering media. Image reconstruction in…

Analysis of PDEs · Mathematics 2015-09-02 Tian Ding , Kui Ren , Sarah Vallelian

In recent years, photoacoustics has attracted intensive research for both anatomical and functional biomedical imaging. However, the physical interaction between photoacoustic generated endogenous waves and an exogenous ultrasound wave is a…

Optics · Physics 2016-01-22 Fei Gao , Xiaohua Feng , Yuanjin Zheng , Claus-Dieter Ohl

We present a method for the recovery of compressively sensed acoustic fields using patterned, instead of point-by-point, detection. From a limited number of such compressed measurements, we propose to reconstruct the field on the sensor…

Numerical Analysis · Mathematics 2016-09-12 Marta M. Betcke , Ben T. Cox , Nam Huynh , Edward Z. Zhang , Paul C. Beard , Simon R. Arridge

Optical wavefront-shaping has emerged as a powerful tool to manipulate light in strongly scattering media. It enables diffraction-limited focusing and imaging at depths where conventional microscopy techniques fail. However, while most…

Optics · Physics 2014-03-04 T. Chaigne , O. Katz , A. C. Boccara , M. Fink , E. Bossy , S. Gigan

Photoacoustic imaging (PAI) is a promising medical imaging modality providing the spatial resolution of ultrasound (US) imaging and the contrast of pure optical imaging. For linear-array PAI, a beamformer has to be used as the…

Medical Physics · Physics 2018-02-15 Moein Mozaffarzadeh , Yan Yan , Mohammad Mehrmohammadi , Bahador Makkiabadi

Localization-based imaging has revolutionized fluorescence optical microscopy and has also enabled unprecedented ultrasound images of microvascular structures in deep tissues. Herein, we introduce a new concept of localization optoacoustic…

Optics · Physics 2017-07-10 Xose Luis Dean-Ben , Daniel Razansky

Integrated photonic sensors can provide large scale, flexible detection schemes. Photonic crystal slabs (PCS) offer a miniaturized platform for wideband, sensitive ultrasound detection by exploiting the photoelastic effect in water.…

Applied Physics · Physics 2021-08-17 Eric Y. Zhu , Maria Charles-Herrera , Cory Rewcastle , Raanan Gad , Li Qian , Ofer Levi

We demonstrate that polarization-sensitive optical coherence tomography (PS-OCT) is suitable to map the stress distribution within materials in a contactless and non-destructive way. In contrast to transmission photoelasticity measurements…

Photoacoustic tomography (PAT) is a novel and promising technology in hybrid medical imaging that involves generating acoustic waves in the object of interest by stimulating electromagnetic energy. The acoustic wave is measured outside the…

Numerical Analysis · Mathematics 2022-08-24 Minam Moon , Injo Hur , Sunghwan Moon

Theranostics, the combination of diagnosis and therapy, has long held promise as a means to achieving personalised precision cancer treatments. However, despite its potential, theranostics has yet to realise significant clinical…

Objective:Optoacoustic (photoacoustic) tomography is aimed at reconstructing maps of the initial pressure rise induced by the absorption of light pulses in tissue. In practice, due to inaccurate assumptions in the forward model, noise and…

Medical Physics · Physics 2019-01-21 Jaya Prakash , Subhamoy Mandal , Daniel Razansky , Vasilis Ntziachristos

Motion, e.g., due to patient movement or improper device calibration, is inevitable in many imaging modalities such as photoacoustic tomography (PAT) by a rotating system and can lead to undesirable motion artifacts in image…

Numerical Analysis · Mathematics 2016-09-28 Julianne Chung , Linh Nguyen

Right Heart Catheterization is a gold standard procedure for diagnosing Pulmonary Hypertension by measuring mean Pulmonary Artery Pressure (mPAP). It is invasive, costly, time-consuming and carries risks. In this paper, for the first time,…

Image and Video Processing · Electrical Eng. & Systems 2024-09-13 Michal K. Grzeszczyk , Przemysław Korzeniowski , Samer Alabed , Andrew J. Swift , Tomasz Trzciński , Arkadiusz Sitek

One of the main applications of photoacoustic (PA) imaging is the recovery of functional tissue properties, such as blood oxygenation (sO2). This is typically achieved by linear spectral unmixing of relevant chromophores from multispectral…

Medical Physics · Physics 2022-04-19 Janek Gröhl , Thomas Kirchner , Tim Adler , Lena Maier-Hein

Multispectral photoacoustic tomography (PAT) is an imaging modality that utilizes the photoacoustic effect to achieve non-invasive and high-contrast imaging of internal tissues. However, the hardware cost and computational demand of a…

Image and Video Processing · Electrical Eng. & Systems 2024-04-11 Yutian Zhong , Xiaoming Zhang , Zongxin Mo , Shuangyang Zhang , Wufan Chen , Li Qi

We present a new nonlinear optimization approach for the sparse reconstruction of single-photon absorption and two-photon absorption coefficients in photoacoustic tomography (PAT). This framework comprises of minimizing an objective…

Optimization and Control · Mathematics 2020-06-30 Madhu Gupta , Rohit Kumar Mishra , Souvik Roy

Based on photoacoustic effect, photoacoustic tomography is developing very fast in recent years, and becoming an important imaging tool for both preclinical and clinical studies. With enough ultrasound transducers placed around the…

Image and Video Processing · Electrical Eng. & Systems 2020-11-13 Jiadong Zhang , Hengrong Lan , Changchun Yang , Shanshan Guo , Feng Gao , Fei Gao

Non-invasive imaging plays a crucial role in diagnosing and studying eye diseases. However, existing photoacoustic ophthalmoscopy (PAOM) techniques in mice have limitations due to handling restrictions, suboptimal optical properties,…

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