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Controlling false positives (Type I errors) through statistical hypothesis testing is a foundation of modern scientific data analysis. Existing causal structure discovery algorithms either do not provide Type I error control or cannot scale…

Methodology · Statistics 2025-12-29 James Leiner , Brian Manzo , Aaditya Ramdas , Wesley Tansey

Using bioimaging technology, biologists have attempted to identify and document analytical interpretations that underlie biological phenomena in biological cells. Theoretical biology aims at distilling those interpretations into knowledge…

Matching in causal inference from observational data aims to construct treatment and control groups with similar distributions of covariates, thereby reducing confounding and ensuring an unbiased estimation of treatment effects. This…

Artificial Intelligence · Computer Science 2025-04-15 Sahil Shikalgar , Md. Noor-E-Alam

Causal inference from observational data following the restricted structural causal models (SCM) framework hinges largely on the asymmetry between cause and effect from the data generating mechanisms, such as non-Gaussianity or…

Machine Learning · Computer Science 2024-05-30 Kang Du , Yu Xiang

Text features that are correlated with class labels, but do not directly cause them, are sometimesuseful for prediction, but they may not be insightful. As an alternative to traditional correlation-basedfeature selection, causal inference…

Machine Learning · Computer Science 2020-10-12 Guohou Shan , James Foulds , Shimei Pan

Gene regulatory networks play a crucial role in controlling an organism's biological processes, which is why there is significant interest in developing computational methods that are able to extract their structure from high-throughput…

Machine Learning · Statistics 2018-09-19 Ioan Gabriel Bucur , Tom van Bussel , Tom Claassen , Tom Heskes

Accurate polyp and cardiac segmentation for early detection and treatment is essential for the diagnosis and treatment planning of cancer-like diseases. Traditional convolutional neural network (CNN) based models have represented limited…

Computer Vision and Pattern Recognition · Computer Science 2025-10-29 Anshul Kaushal , Kunal Jangid , Vinod K. Kurmi

The causal inference literature has increasingly recognized that explicitly targeting treatment effect heterogeneity can lead to improved scientific understanding and policy recommendations. Towards the same ends, studying the causal…

Methodology · Statistics 2023-03-06 Angela Ting , Antonio R. Linero

The paper concerns the problem of predicting the effect of actions or interventions on a system from a combination of (i) statistical data on a set of observed variables, and (ii) qualitative causal knowledge encoded in the form of a…

Artificial Intelligence · Computer Science 2012-07-02 Carlos Brito , Judea Pearl

Resting-state functional magnetic resonance imaging (rs-fMRI) is a noninvasive technique pivotal for understanding human neural mechanisms of intricate cognitive processes. Most rs-fMRI studies compute a single static functional…

Neurons and Cognition · Quantitative Biology 2025-02-25 Bishal Thapaliya , Robyn Miller , Jiayu Chen , Yu-Ping Wang , Esra Akbas , Ram Sapkota , Bhaskar Ray , Pranav Suresh , Santosh Ghimire , Vince Calhoun , Jingyu Liu

Due to its inferior characteristics, an observed (noisy) image's direct use gives rise to poor segmentation results. Intuitively, using its noise-free image can favorably impact image segmentation. Hence, the accurate estimation of the…

Image and Video Processing · Electrical Eng. & Systems 2020-10-12 Cong Wang , Witold Pedrycz , ZhiWu Li , MengChu Zhou

Causal models have proven extremely useful in offering formal representations of causal relationships between a set of variables. Yet in many situations, there are non-causal relationships among variables. For example, we may want variables…

Artificial Intelligence · Computer Science 2023-01-18 Sander Beckers , Joseph Y. Halpern , Christopher Hitchcock

We present a novel image-based adaptive domain decomposition FEM framework to accelerate the solution of continuum damage mechanics problems. The key idea is to use image-processing techniques in order to identify the moving interface…

Computational Engineering, Finance, and Science · Computer Science 2024-11-08 Panos Pantidis , Cornelius Otchere , Mostafa E. Mobasher

Three distinct phenomena complicate statistical causal analysis: latent common causes, causal cycles, and latent selection. Foundational works on Structural Causal Models (SCMs), e.g., Bongers et al. (2021, Ann. Stat., 49(5): 2885-2915),…

Methodology · Statistics 2025-11-23 Leihao Chen , Onno Zoeter , Joris M. Mooij

Contemporary neuroimaging methods can shed light on the basis of human neural and cognitive specializations, with important implications for neuroscience and medicine. Different MRI acquisitions provide different brain networks at the…

Neurons and Cognition · Quantitative Biology 2016-02-23 C. Alonso-Montes , I. Diez , L. Remaki , I. Escudero , B. Mateos , Y. Rosseel , D. Marinazzo , S. Stramaglia , J. Cortes

As the rapid development of computer vision and the emergence of powerful network backbones and architectures, the application of deep learning in medical imaging has become increasingly significant. Unlike natural images, medical images…

Image and Video Processing · Electrical Eng. & Systems 2026-04-10 Guoqing Zhang , Jingyun Yang , Yang Li

A data science task can be deemed as making sense of the data or testing a hypothesis about it. The conclusions inferred from data can greatly guide us to make informative decisions. Big data has enabled us to carry out countless prediction…

Machine Learning · Computer Science 2022-01-12 Wenhao Zhang , Ramin Ramezani , Arash Naeim

Medical image segmentation is crucial for computer-aided diagnosis, yet privacy constraints hinder data sharing across institutions. Federated learning addresses this limitation, but existing approaches often rely on lightweight…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Tong Wang , Xingyue Zhao , Linghao Zhuang , Haoyu Zhao , Jiayi Yin , Yuyang He , Gang Yu , Bo Lin

Evaluating causal treatment effects in observational studies requires addressing confounding. While the back-door criterion enables identification through adjustment for observed covariates, it fails in the presence of unmeasured…

Methodology · Statistics 2026-05-04 Anna Guo , David Benkeser , Razieh Nabi

This article discusses how the language of causality can shed new light on the major challenges in machine learning for medical imaging: 1) data scarcity, which is the limited availability of high-quality annotations, and 2) data mismatch,…

Image and Video Processing · Electrical Eng. & Systems 2020-07-23 Daniel C. Castro , Ian Walker , Ben Glocker