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Despite recent advances in medical image generation, existing methods struggle to produce anatomically plausible 3D structures. In synthetic brain magnetic resonance images (MRIs), characteristic fissures are often missing, and…

Computer Vision and Pattern Recognition · Computer Science 2025-02-19 Fabian Bongratz , Yitong Li , Sama Elbaroudy , Christian Wachinger

The reconstruction of cortical surfaces from brain magnetic resonance imaging (MRI) scans is essential for quantitative analyses of cortical thickness and sulcal morphology. Although traditional and deep learning-based algorithmic pipelines…

Computer Vision and Pattern Recognition · Computer Science 2022-03-21 Fabian Bongratz , Anne-Marie Rickmann , Sebastian Pölsterl , Christian Wachinger

Deep neural networks have brought remarkable breakthroughs in medical image analysis. However, due to their data-hungry nature, the modest dataset sizes in medical imaging projects might be hindering their full potential. Generating…

Cortical surface analysis has gained increased prominence, given its potential implications for neurological and developmental disorders. Traditional vision diffusion models, while effective in generating natural images, present limitations…

Image and Video Processing · Electrical Eng. & Systems 2024-02-08 Zhenshan Xie , Simon Dahan , Logan Z. J. Williams , M. Jorge Cardoso , Emma C. Robinson

Recent advances in generative models for medical imaging have shown promise in representing multiple modalities. However, the variability in modality availability across datasets limits the general applicability of the synthetic data they…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Sven Lüpke , Yousef Yeganeh , Ehsan Adeli , Nassir Navab , Azade Farshad

Understanding and predicting the progression of neurodegenerative diseases remains a major challenge in medical AI, with significant implications for early diagnosis, disease monitoring, and treatment planning. However, most available…

Computer Vision and Pattern Recognition · Computer Science 2026-04-27 Nivetha Jayakumar , Swakshar Deb , Bahram Jafrasteh , Qingyu Zhao , Miaomiao Zhang

Human anatomy, morphology, and associated diseases can be studied using medical imaging data. However, access to medical imaging data is restricted by governance and privacy concerns, data ownership, and the cost of acquisition, thus…

Generating ground-level images from aerial views is a challenging task due to extreme viewpoint disparity, occlusions, and a limited field of view. We introduce Top2Ground, a novel diffusion-based method that directly generates…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Jae Joong Lee , Bedrich Benes

Due to the low signal-to-noise ratio and limited resolution of functional MRI data, and the high complexity of natural images, reconstructing a visual stimulus from human brain fMRI measurements is a challenging task. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2023-03-07 Zijin Gu , Keith Jamison , Amy Kuceyeski , Mert Sabuncu

Generative models have achieved success in producing semantically plausible 2D images, but it remains challenging in 3D generation due to the absence of spatial geometry constraints. Typically, existing methods utilize geometric features as…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Haonan Wang , Hanyu Zhou , Haoyue Liu , Tao Gu , Luxin Yan

A long standing goal in neuroscience has been to elucidate the functional organization of the brain. Within higher visual cortex, functional accounts have remained relatively coarse, focusing on regions of interest (ROIs) and taking the…

Computer Vision and Pattern Recognition · Computer Science 2023-11-29 Andrew F. Luo , Margaret M. Henderson , Leila Wehbe , Michael J. Tarr

The work proposes a novel deep-learning framework for the synthesis of three-dimensional MRI volumes from corresponding 3D ultrasound images of the brain, leveraging a modified iteration of the Pix2Pix Generative Adversarial Network (GAN)…

Image and Video Processing · Electrical Eng. & Systems 2024-07-19 Shubham Singh , Mrunal Bewoor , Ammar Ranapurwala , Satyam Rai , Sheetal Patil

The reconstruction of cortical surfaces is a prerequisite for quantitative analyses of the cerebral cortex in magnetic resonance imaging (MRI). Existing segmentation-based methods separate the surface registration from the surface…

Image and Video Processing · Electrical Eng. & Systems 2024-03-05 Fabian Bongratz , Anne-Marie Rickmann , Christian Wachinger

3D brain MRI studies often examine subtle morphometric differences between cohorts that are hard to detect visually. Given the high cost of MRI acquisition, these studies could greatly benefit from image syntheses, particularly…

Computer Vision and Pattern Recognition · Computer Science 2025-09-12 Binxu Li , Wei Peng , Mingjie Li , Ehsan Adeli , Kilian M. Pohl

Analyzing and predicting brain aging is essential for early prognosis and accurate diagnosis of cognitive diseases. The technique of neuroimaging, such as Magnetic Resonance Imaging (MRI), provides a noninvasive means of observing the aging…

Image and Video Processing · Electrical Eng. & Systems 2022-12-06 Jingru Fu , Antonios Tzortzakakis , José Barroso , Eric Westman , Daniel Ferreira , Rodrigo Moreno

Magnetic resonance imaging (MRI) inpainting supports numerous clinical and research applications. We introduce the first generative model that conditions on voxel-level, continuous tumor concentrations to synthesize high-fidelity brain…

Image and Video Processing · Electrical Eng. & Systems 2025-12-09 Valentin Biller , Lucas Zimmer , Ayhan Can Erdur , Sandeep Nagar , Daniel Rückert , Niklas Bubeck , Jonas Weidner

Designing generative models for 3D structural brain MRI that synthesize morphologically-plausible and attribute-specific (e.g., age, sex, disease state) samples is an active area of research. Existing approaches based on frameworks like…

Image and Video Processing · Electrical Eng. & Systems 2025-08-04 Alan Q. Wang , Fangrui Huang , Bailey Trang , Wei Peng , Mohammad Abbasi , Kilian Pohl , Mert Sabuncu , Ehsan Adeli

Synthetic longitudinal brain MRI simulates brain aging and would enable more efficient research on neurodevelopmental and neurodegenerative conditions. Synthetically generated, age-adjusted brain images could serve as valuable alternatives…

Signal Processing · Electrical Eng. & Systems 2024-05-03 Anna Zapaishchykova , Benjamin H. Kann , Divyanshu Tak , Zezhong Ye , Daphne A. Haas-Kogan , Hugo J. W. L. Aerts

Generative AI models hold great potential in creating synthetic brain MRIs that advance neuroimaging studies by, for example, enriching data diversity. However, the mainstay of AI research only focuses on optimizing the visual quality (such…

Image and Video Processing · Electrical Eng. & Systems 2023-10-10 Wei Peng , Tomas Bosschieter , Jiahong Ouyang , Robert Paul , Ehsan Adeli , Qingyu Zhao , Kilian M. Pohl

We introduce a new technique for generating retinal fundus images that have anatomically accurate vascular structures, using diffusion models. We generate artery/vein masks to create the vascular structure, which we then condition to…

Image and Video Processing · Electrical Eng. & Systems 2023-05-12 Sojung Go , Younghoon Ji , Sang Jun Park , Soochahn Lee
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