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In medical image segmentation, uncertainty estimates are often reported but rarely used to guide decisions. We study the missing step: how uncertainty maps are converted into actionable policies such as accepting, flagging, or deferring…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Saket Maganti

It is difficult to accurately label ambiguous and complex shaped targets manually by binary masks. The weakness of binary mask under-expression is highlighted in medical image segmentation, where blurring is prevalent. In the case of…

Computer Vision and Pattern Recognition · Computer Science 2022-01-04 Lin Wang , Lie Ju , Xin Wang , Wanji He , Donghao Zhang , Yelin Huang , Zhiwen Yang , Xuan Yao , Xin Zhao , Xiufen Ye , Zongyuan Ge

Accurate brain image segmentation, particularly for distinguishing various tissues from magnetic resonance imaging (MRI) images, plays a pivotal role in finding the neurological dis ease and medical image computing. In deep learning…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Hanuman Verma , Akshansh Gupta , Pranabesh Maji , Saurav Mandal , Vijay Kumar Pandey

Aleatoric uncertainty is an intrinsic property of ill-posed inverse and imaging problems. Its quantification is vital for assessing the reliability of relevant point estimates. In this paper, we propose an efficient framework for…

Image and Video Processing · Electrical Eng. & Systems 2020-01-16 Chen Zhang , Bangti Jin

Accurate uncertainty estimation is a critical need for the medical imaging community. A variety of methods have been proposed, all direct extensions of classification uncertainty estimations techniques. The independent pixel-wise…

Image and Video Processing · Electrical Eng. & Systems 2022-06-16 Thierry Judge , Olivier Bernard , Mihaela Porumb , Agis Chartsias , Arian Beqiri , Pierre-Marc Jodoin

Medical image segmentation plays a crucial role in clinical workflows, but domain shift often leads to performance degradation when models are applied to unseen clinical domains. This challenge arises due to variations in imaging…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Yingkai Wang , Yaoyao Zhu , Xiuding Cai , Yuhao Xiao , Haotian Wu , Yu Yao

Automatic medical image segmentation is a fundamental step in computer-aided diagnosis, yet fully supervised approaches demand extensive pixel-level annotations that are costly and time-consuming. To alleviate this burden, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Lei Shi , Gang Li , Junxing Zhang

The production of thematic maps depicting land cover is one of the most common applications of remote sensing. To this end, several semantic segmentation approaches, based on deep learning, have been proposed in the literature, but land…

Computer Vision and Pattern Recognition · Computer Science 2018-05-30 Guillem Pascual , Santi Seguí , Jordi Vitrià

Inverse problems play a key role in modern image/signal processing methods. However, since they are generally ill-conditioned or ill-posed due to lack of observations, their solutions may have significant intrinsic uncertainty. Analysing…

Signal Processing · Electrical Eng. & Systems 2019-09-09 Xiaohao Cai , Marcelo Pereyra , Jason D. McEwen

Accurate lesion segmentation is crucial for clinical diagnosis and treatment planning. However, lesions often resemble surrounding tissues and exhibit ill-defined boundaries, leading to unstable predictions in boundary/transition regions.…

Computer Vision and Pattern Recognition · Computer Science 2026-05-01 Shuokun Cheng , Jinghao Shi , Kun Sun

Uncertainty quantification in medical images has become an essential addition to segmentation models for practical application in the real world. Although there are valuable developments in accurate uncertainty quantification methods using…

Image and Video Processing · Electrical Eng. & Systems 2023-05-02 Christiaan G. A. Viviers , Amaan M. M. Valiuddin , Peter H. N. de With , Fons van der Sommen

Despite the recent success of deep learning methods at achieving new state-of-the-art accuracy for medical image segmentation, some major limitations are still restricting their deployment into clinics. One major limitation of deep…

Image and Video Processing · Electrical Eng. & Systems 2023-05-30 Lucas Fidon

Quantifying aleatoric uncertainty in medical image segmentation is critical since it is a reflection of the natural variability observed among expert annotators. A conventional approach is to model the segmentation distribution using the…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Phi Van Nguyen , Ngoc Huynh Trinh , Duy Minh Lam Nguyen , Phu Loc Nguyen , Quoc Long Tran

Object segmentation plays an important role in the modern medical image analysis, which benefits clinical study, disease diagnosis, and surgery planning. Given the various modalities of medical images, the automated or semi-automated…

Image and Video Processing · Electrical Eng. & Systems 2020-06-01 Dong Yang , Holger Roth , Xiaosong Wang , Ziyue Xu , Andriy Myronenko , Daguang Xu

In medical imaging, inter-observer variability among radiologists often introduces label uncertainty, particularly in modalities where visual interpretation is subjective. Lung ultrasound (LUS) is a prime example-it frequently presents a…

Probabilistic image segmentation encodes varying prediction confidence and inherent ambiguity in the segmentation problem. While different probabilistic segmentation models are designed to capture different aspects of segmentation…

Computer Vision and Pattern Recognition · Computer Science 2021-03-31 Steffen Czolbe , Kasra Arnavaz , Oswin Krause , Aasa Feragen

Image segmentation is a challenging task influenced by multiple sources of uncertainty, such as the data labeling process or the sampling of training data. In this paper we focus on binary segmentation and address these challenges using…

Computer Vision and Pattern Recognition · Computer Science 2025-03-10 Luca Mossina , Corentin Friedrich

Active learning is a unique abstraction of machine learning techniques where the model/algorithm could guide users for annotation of a set of data points that would be beneficial to the model, unlike passive machine learning. The primary…

Computer Vision and Pattern Recognition · Computer Science 2021-01-08 Vishwesh Nath , Dong Yang , Bennett A. Landman , Daguang Xu , Holger R. Roth

Accurate brain tumor segmentation from MRI scans is critical for diagnosis and treatment planning. Despite the strong performance of recent deep learning approaches, two fundamental limitations remain: (1) the lack of reliable uncertainty…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Bahram Mohammadi , Yanqiu Wu , Vu Minh Hieu Phan , Sam White , Minh-Son To , Jian Yang , Michael Sheng , Yang Song , Yuankai Qi

Parallel imaging techniques reduce magnetic resonance imaging (MRI) scan time but image quality degrades as the acceleration factor increases. In clinical practice, conservative acceleration factors are chosen because no mechanism exists to…

Image and Video Processing · Electrical Eng. & Systems 2026-05-26 Ilias I. Giannakopoulos , Lokesh B Gautham Muthukumar , Yvonne W. Lui , Riccardo Lattanzi