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We propose a novel method for estimating heterogeneous treatment effects based on the fused lasso. By first ordering samples based on the propensity or prognostic score, we match units from the treatment and control groups. We then run the…

Medical image segmentation is a key task in the imaging workflow, influencing many image-based decisions. Traditional, fully-supervised segmentation models rely on large amounts of labeled training data, typically obtained through manual…

Image and Video Processing · Electrical Eng. & Systems 2025-11-04 Tyler Ward , Meredith K. Owen , O'Kira Coleman , Brian Noehren , Abdullah-Al-Zubaer Imran

Manual chart review remains an extremely time-consuming and resource-intensive component of clinical research, requiring experts to extract often complex information from unstructured electronic health record (EHR) narratives. We present a…

Predicting medications is a crucial task in many intelligent healthcare systems. It can assist doctors in making informed medication decisions for patients according to electronic medical records (EMRs). However, medication prediction is a…

Artificial Intelligence · Computer Science 2022-05-02 Yang An , Bo Jin , Xiaopeng Wei

Session-based recommendation (SBR) predicts the next item based on anonymous sessions. Traditional SBR explores user intents based on ID collaborations or auxiliary content. To further alleviate data sparsity and cold-start issues, recent…

Information Retrieval · Computer Science 2025-04-16 Jiajie Su , Qiyong Zhong , Yunshan Ma , Weiming Liu , Chaochao Chen , Xiaolin Zheng , Jianwei Yin , Tat-Seng Chua

We consider the problem of modularizing control flow in a generic abstract interpretation framework. A generic abstract interpretation framework is not truly flexible if it does not allow interpreting with different path- and…

Programming Languages · Computer Science 2026-02-19 Cade Lueker , Andrew Fox , Bor-Yuh Evan Chang

Autoregressive models can predict clinical events, but generating patient-conditioned multi-step trajectories that respond to intervention tokens and testing whether those responses preserve known pharmacological associations has received…

Machine Learning · Computer Science 2026-05-07 Chris Sainsbury , Feng Dong , Andreas Karwath

Despite rapid advances in large language models (LLMs), their integration with traditional supervised machine learning (ML) techniques that have proven applicability to medical data remains underexplored. This is particularly true for…

Computation and Language · Computer Science 2025-05-28 Yuxin Zhu , Yuting Guo , Noah Marchuck , Abeed Sarker , Yun Wang

We propose a novel framework for integrating fragmented multi-modal data in Alzheimer's disease (AD) research using large language models (LLMs) and knowledge graphs. While traditional multimodal analysis requires matched patient IDs across…

Machine Learning · Computer Science 2025-08-19 Kanan Kiguchi , Yunhao Tu , Katsuhiro Ajito , Fady Alnajjar , Kazuyuki Murase

Development of new medications is a very lengthy and costly process. Finding novel indications for existing drugs, or drug repositioning, can serve as a useful strategy to shorten the development cycle. In this study, we present an approach…

Genomics · Quantitative Biology 2017-12-13 Kai Zhao , Hon-Cheong So

Structural causal models (SCMs) allow us to investigate complex systems at multiple levels of resolution. The causal abstraction (CA) framework formalizes the mapping between high- and low-level SCMs. We address CA learning in a challenging…

Machine Learning · Computer Science 2025-06-03 Gabriele D'Acunto , Fabio Massimo Zennaro , Yorgos Felekis , Paolo Di Lorenzo

Neural abstractive summarization models are flexible and can produce coherent summaries, but they are sometimes unfaithful and can be difficult to control. While previous studies attempt to provide different types of guidance to control the…

Computation and Language · Computer Science 2021-04-20 Zi-Yi Dou , Pengfei Liu , Hiroaki Hayashi , Zhengbao Jiang , Graham Neubig

Recent progress in deep learning is revolutionizing the healthcare domain including providing solutions to medication recommendations, especially recommending medication combination for patients with complex health conditions. Existing…

Artificial Intelligence · Computer Science 2019-03-08 Junyuan Shang , Cao Xiao , Tengfei Ma , Hongyan Li , Jimeng Sun

Drug discovery remains a formidable challenge: more than 90 percent of candidate molecules fail in clinical evaluation, and development costs often exceed one billion dollars per approved therapy. Disparate data streams, from genomics and…

Artificial Intelligence · Computer Science 2025-04-28 Kevin Song , Andrew Trotter , Jake Y. Chen

Chart summarization is crucial for enhancing data accessibility and the efficient consumption of information. However, existing methods, including those with Multimodal Large Language Models (MLLMs), primarily focus on low-level data…

Artificial Intelligence · Computer Science 2026-02-24 Yuhang Bai , Yujuan Ding , Shanru Lin , Wenqi Fan

The success of scene graphs for visual scene understanding has brought attention to the benefits of abstracting a visual input (e.g., image) into a structured representation, where entities (people and objects) are nodes connected by edges…

Computer Vision and Pattern Recognition · Computer Science 2022-10-28 Mohamed Ashraf Abdelsalam , Zhan Shi , Federico Fancellu , Kalliopi Basioti , Dhaivat J. Bhatt , Vladimir Pavlovic , Afsaneh Fazly

Multimodal data are now prevailing in scientific research. A central question in multimodal integrative analysis is to understand how two data modalities associate and interact with each other given another modality or demographic…

Methodology · Statistics 2021-04-27 Lexin Li , Jing Zeng , Xin Zhang

Abstraction is essential for reducing the complexity of systems across diverse fields, yet designing effective abstraction methodology for probabilistic models is inherently challenging due to stochastic behaviors and uncertainties. Current…

Artificial Intelligence · Computer Science 2025-03-03 Nijesh Upreti , Vaishak Belle

Tabular data is often hidden in text, particularly in medical diagnostic reports. Traditional machine learning (ML) models designed to work with tabular data, cannot effectively process information in such form. On the other hand, large…

Machine Learning · Computer Science 2023-06-09 Aleksa Bisercic , Mladen Nikolic , Mihaela van der Schaar , Boris Delibasic , Pietro Lio , Andrija Petrovic

Predicting patient mortality is an important and challenging problem in the healthcare domain, especially for intensive care unit (ICU) patients. Electronic health notes serve as a rich source for learning patient representations, that can…

Computation and Language · Computer Science 2019-10-16 Shaika Chowdhury , Chenwei Zhang , Philip S. Yu , Yuan Luo