English
Related papers

Related papers: Structure-based RNA Design by Step-wise Optimizati…

200 papers

Integrative biomolecular modeling of RNA relies on structural refined collections and accurate experimental data that reflect binding and folding behavior. However, the prediction of such collections remains challenging due to the rugged…

Dynamic resource allocation in mobile wireless networks involves complex, time-varying optimization problems, motivating the adoption of deep reinforcement learning (DRL). However, most existing works rely on pre-trained policies,…

Machine Learning · Computer Science 2025-02-12 Xinren Zhang , Jiadong Yu

Computed Tomography (CT) is a widely utilized imaging modality in clinical settings. Using densely acquired rotational X-ray arrays, CT can capture 3D spatial features. However, it is confronted with challenged such as significant time…

Image and Video Processing · Electrical Eng. & Systems 2025-07-16 Duoyou Chen , Yunqing Chen , Can Zhang , Zhou Wang , Cheng Chen , Ruoxiu Xiao

Online reinforcement learning (RL) has been central to post-training language models, but its extension to diffusion models remains challenging due to intractable likelihoods. Recent works discretize the reverse sampling process to enable…

Machine Learning · Computer Science 2026-02-17 Kaiwen Zheng , Huayu Chen , Haotian Ye , Haoxiang Wang , Qinsheng Zhang , Kai Jiang , Hang Su , Stefano Ermon , Jun Zhu , Ming-Yu Liu

Controlling the degree of stylization in the Neural Style Transfer (NST) is a little tricky since it usually needs hand-engineering on hyper-parameters. In this paper, we propose the first deep Reinforcement Learning (RL) based architecture…

Computer Vision and Pattern Recognition · Computer Science 2024-08-15 Chengming Feng , Jing Hu , Xin Wang , Shu Hu , Bin Zhu , Xi Wu , Hongtu Zhu , Siwei Lyu

Discrete diffusion models (DDMs) have shown powerful generation ability for discrete data modalities like text and molecules. However, their practical application is hindered by inefficient sampling, requiring a large number of sampling…

Machine Learning · Computer Science 2025-09-25 Feiyang Fu , Tongxian Guo , Zhaoqiang Liu

Diffusion models recently emerged as a powerful paradigm for recommender systems, offering state-of-the-art performance by modeling the generative process of user-item interactions. However, training such models from scratch is both…

Information Retrieval · Computer Science 2025-11-11 Yu Hou , Hua Li , Ha Young Kim , Won-Yong Shin

Recent advances in one-step text-to-image generation have enabled real-time synthesis with remarkable efficiency and quality. Previous reinforcement learning methods for one-step generators combine image-space reward optimization with…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Junyi Wu , Weijian Luo , Haoyang Zheng , Ruizhe Zhang , Guang Lin

We propose Diffusion-Sharpening, a fine-tuning approach that enhances downstream alignment by optimizing sampling trajectories. Existing RL-based fine-tuning methods focus on single training timesteps and neglect trajectory-level alignment,…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Ye Tian , Ling Yang , Xinchen Zhang , Yunhai Tong , Mengdi Wang , Bin Cui

Continuous monitoring and real-time control of high-dimensional distributed systems are often crucial in applications to ensure a desired physical behavior, without degrading stability and system performances. Traditional feedback control…

Optimization and Control · Mathematics 2024-12-16 Matteo Tomasetto , Francesco Braghin , Andrea Manzoni

Motivation: RNA design aims to find RNA sequences that fold into a given target secondary structure, a problem also known as RNA inverse folding. However, not all target structures are designable. Recent advances in RNA designability have…

Data Structures and Algorithms · Computer Science 2026-04-28 Tianshuo Zhou , David H. Mathews , Liang Huang

Inverse reinforcement learning (IRL) for linear systems seeks a cost function whose optimal controller reproduces an expert policy from data. Existing data-driven methods for discrete-time linear systems are largely built on iterative…

Systems and Control · Electrical Eng. & Systems 2026-05-12 Duc Cuong Nguyen , Phuong Nam Dao

Machine learning (ML) models trained using Empirical Risk Minimization (ERM) often exhibit systematic errors on specific subpopulations of tabular data, known as error slices. Learning robust representation in presence of error slices is…

Machine Learning · Computer Science 2025-11-10 Shantanu Ghosh , Tiankang Xie , Mikhail Kuznetsov

Reinforcement learning for training end-to-end autonomous driving models in closed-loop simulations is gaining growing attention. However, most simulation environments differ significantly from real-world conditions, creating a substantial…

Computer Vision and Pattern Recognition · Computer Science 2025-08-22 Chaojun Ni , Guosheng Zhao , Xiaofeng Wang , Zheng Zhu , Wenkang Qin , Xinze Chen , Guanghong Jia , Guan Huang , Wenjun Mei

Diffusion language models (dLLMs) recently emerged as a promising alternative to auto-regressive LLMs. The latest works further extended it to multimodal understanding and generation tasks. In this work, we propose LaViDa-R1, a multimodal,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Shufan Li , Yuchen Zhu , Jiuxiang Gu , Kangning Liu , Zhe Lin , Yongxin Chen , Molei Tao , Aditya Grover , Jason Kuen

Inverse problems are pervasive mathematical methods in inferring knowledge from observational and experimental data by leveraging simulations and models. Unlike direct inference methods, inverse problem approaches typically require many…

Computational Physics · Physics 2019-12-20 Sheroze Sheriffdeen , Jean C. Ragusa , Jim E. Morel , Marvin L. Adams , Tan Bui-Thanh

This article proposes a model-based deep reinforcement learning (DRL) method to design emergency control strategies for short-term voltage stability problems in power systems. Recent advances show promising results in model-free DRL-based…

Systems and Control · Electrical Eng. & Systems 2022-12-07 Ramij R. Hossain , Tianzhixi Yin , Yan Du , Renke Huang , Jie Tan , Wenhao Yu , Yuan Liu , Qiuhua Huang

Reinforcement-Learning-based post-training has recently emerged as a promising paradigm for aligning text-to-image diffusion models with human preferences. In recent studies, increasing the rollout group size yields pronounced performance…

Machine Learning · Computer Science 2026-04-09 Yitong Li , Junsong Chen , Shuchen Xue , Pengcuo Zeren , Siyuan Fu , Dinghao Yang , Yangyang Tang , Junjie Bai , Ping Luo , Song Han , Enze Xie

Multi-dimensional data streams, prevalent in applications like IoT, financial markets, and real-time analytics, pose significant challenges due to their high velocity, unbounded nature, and complex inter-dimensional dependencies. Sliding…

Machine Learning · Computer Science 2025-07-10 Abolfazl Zarghani , Sadegh Abedi

Reinforcement Learning (RL), bolstered by the expressive capabilities of Deep Neural Networks (DNNs) for function approximation, has demonstrated considerable success in numerous applications. However, its practicality in addressing various…

Machine Learning · Computer Science 2024-04-26 Aditya Mohan , Amy Zhang , Marius Lindauer