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While Conformal Prediction (CP) has proven to be a powerful framework for uncertainty quantification, guaranteeing conditional coverage remains a central challenge. Although finite-sample, distribution-free conditional validity is known to…

Methodology · Statistics 2026-05-27 Félix Laplante

Operating System (OS) fingerprinting is critical for network security, but conventional methods do not provide formal uncertainty quantification mechanisms. Conformal Prediction (CP) could be directly wrapped around existing methods to…

Cryptography and Security · Computer Science 2026-02-16 Rubén Pérez-Jove , Osvaldo Simeone , Alejandro Pazos , Jose Vázquez-Naya

Convolutional neural networks (CNN) have had unprecedented success in medical imaging and, in particular, in medical image segmentation. However, despite the fact that segmentation results are closer than ever to the inter-expert…

Computer Vision and Pattern Recognition · Computer Science 2020-06-17 Nathan Painchaud , Youssef Skandarani , Thierry Judge , Olivier Bernard , Alain Lalande , Pierre-Marc Jodoin

Conformal prediction provides finite-sample, distribution-free coverage under exchangeability, but standard constructions may lack robustness in the presence of outliers or heavy tails. We propose a robust conformal method based on a…

Statistics Theory · Mathematics 2026-04-21 Alejandro Cholaquidis , Emilien Joly , Leonardo Moreno

Conformal prediction (CP) offers a principled framework for uncertainty quantification, but it fails to guarantee coverage when faced with missing covariates. In addressing the heterogeneity induced by various missing patterns,…

Machine Learning · Statistics 2025-12-17 Jiarong Fan , Juhyun Park. Thi Phuong Thuy Vo , Nicolas Brunel

The task of parsing subcutaneous vessels in clinical images is often hindered by the high cost and limited availability of ground truth data, as well as the challenge of low contrast and noisy vessel appearances across different patients…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Ayaan Nooruddin Siddiqui , Mahnoor Zaidi , Ayesha Nazneen Shahbaz , Priyadarshini Chatterjee , Krishnan Menon Iyer

In recent years, deep learning based methods have shown success in essential medical image analysis tasks such as segmentation. Post-processing and refining the results of segmentation is a common practice to decrease the misclassifications…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 Ufuk Demir , Atahan Ozer , Yusuf H. Sahin , Gozde Unal

Graph embedding based on random-walks supports effective solutions for many graph-related downstream tasks. However, the abundance of embedding literature has made it increasingly difficult to compare existing methods and to identify…

Machine Learning · Computer Science 2021-10-26 Zexi Huang , Arlei Silva , Ambuj Singh

Conformal Prediction (CP) has emerged as a powerful statistical framework for high-stakes classification applications. Instead of predicting a single class, CP generates a prediction set, guaranteed to include the true label with a…

Machine Learning · Computer Science 2025-11-25 Ariel Fargion , Lahav Dabah , Tom Tirer

Conformal prediction provides a pivotal and flexible technique for uncertainty quantification by constructing prediction sets with a predefined coverage rate. Many online conformal prediction methods have been developed to address data…

Machine Learning · Statistics 2026-02-25 Dongjian Hu , Junxi Wu , Shu-Tao Xia , Changliang Zou

We consider the problem of segmenting a biomedical image into anatomical regions of interest. We specifically address the frequent scenario where we have no paired training data that contains images and their manual segmentations. Instead,…

Computer Vision and Pattern Recognition · Computer Science 2019-03-14 Adrian V. Dalca , John Guttag , Mert R. Sabuncu

Uncertainty quantification is necessary for developers, physicians, and regulatory agencies to build trust in machine learning predictors and improve patient care. Beyond measuring uncertainty, it is crucial to express it in clinically…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Jacopo Teneggi , J Webster Stayman , Jeremias Sulam

Conformal Prediction (CP) quantifies network uncertainty by building a small prediction set with a pre-defined probability that the correct class is within this set. In this study we tackle the problem of CP calibration based on a…

Machine Learning · Computer Science 2024-05-22 Coby Penso , Jacob Goldberger

Medical image segmentation is usually regarded as one of the most important intermediate steps in clinical situations and medical imaging research. Thus, accurately assessing the segmentation quality of the automatically generated…

Image and Video Processing · Electrical Eng. & Systems 2022-01-19 Zhenxi Zhang , Chunna Tian , Jie Li , Zhusi Zhong , Zhicheng Jiao , Xinbo Gao

Semantic segmentation is a core task in computer vision with applications in biomedical imaging, remote sensing, and autonomous driving. While standard loss functions such as cross-entropy and Dice loss perform well in general cases, they…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Renhao Lu

Conformal prediction constructs a confidence set for an unobserved response of a feature vector based on previous identically distributed and exchangeable observations of responses and features. It has a coverage guarantee at any nominal…

Machine Learning · Statistics 2022-12-08 Eugene Ndiaye , Ichiro Takeuchi

Deep learning has the potential to automate many clinically useful tasks in medical imaging. However translation of deep learning into clinical practice has been hindered by issues such as lack of the transparency and interpretability in…

Image and Video Processing · Electrical Eng. & Systems 2022-05-04 Charles Lu , Andreanne Lemay , Ken Chang , Katharina Hoebel , Jayashree Kalpathy-Cramer

Conformal prediction is widely used to equip black-box machine learning models with uncertainty quantification, offering formal coverage guarantees under exchangeable data. However, these guarantees fail when faced with subpopulation…

Machine Learning · Computer Science 2025-11-10 Nien-Shao Wang , Duygu Nur Yaldiz , Yavuz Faruk Bakman , Sai Praneeth Karimireddy

Instance segmentation plays a pivotal role in medical image analysis by enabling precise localization and delineation of lesions, tumors, and anatomical structures. Although deep learning models such as Mask R-CNN and BlendMask have…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Mengxia Dai , Wenqian Luo , Tianyang Li

Conformal prediction (CP) has become a cornerstone of distribution-free uncertainty quantification, conventionally evaluated by its coverage and interval length. This work critically examines the sufficiency of these standard metrics. We…

Machine Learning · Statistics 2026-01-30 Yizhou Min , Yizhou Lu , Lanqi Li , Zhen Zhang , Jiaye Teng