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Motivated by DNA-based storage applications, we study the problem of reconstructing a coded sequence from multiple traces. We consider the model where the traces are outputs of independent deletion channels, where each channel deletes each…

Information Theory · Computer Science 2022-07-13 Serge Kas Hanna

Recursive Bayesian inference, in which posterior beliefs are updated in light of accumulating data, is a tool for implementing Bayesian models in applications with streaming and/or very large data sets. As the posterior of one iteration…

Methodology · Statistics 2025-08-05 Henry R. Scharf

The insertion-deletion channel takes as input a bit string ${\bf x}\in\{0,1\}^{n}$, and outputs a string where bits have been deleted and inserted independently at random. The trace reconstruction problem is to recover $\bf x$ from many…

Probability · Mathematics 2020-04-28 Nina Holden , Robin Pemantle , Yuval Peres , Alex Zhai

This paper extends the applications of belief-networks to include the revision of belief commitments, i.e., the categorical acceptance of a subset of hypotheses which, together, constitute the most satisfactory explanation of the evidence…

Artificial Intelligence · Computer Science 2013-04-12 Judea Pearl

Near optimal decoding of good error control codes is generally a difficult task. However, for a certain type of (sufficiently) good codes an efficient decoding algorithm with near optimal performance exists. These codes are defined via a…

Information Theory · Computer Science 2007-10-30 Uli Sorger

Recent emergence of next-generation DNA sequencing technology has enabled acquisition of genetic information at unprecedented scales. In order to determine the genetic blueprint of an organism, sequencing platforms typically employ…

Genomics · Quantitative Biology 2015-06-19 Xiaohu Shen , Manohar Shamaiah , Haris Vikalo

We propose a systematic method for constructing a sparse data reconstruction algorithm in compressed sensing at a relatively low computational cost for general observation matrix. It is known that the cost of l1-norm minimization using a…

Information Theory · Computer Science 2014-04-10 Koujin Takeda , Yoshiyuki Kabashima

We present a universal framework for constructing confidence sets based on sequential likelihood mixing. Building upon classical results from sequential analysis, we provide a unifying perspective on several recent lines of work, and…

Machine Learning · Statistics 2025-02-21 Johannes Kirschner , Andreas Krause , Michele Meziu , Mojmir Mutny

We consider the problem of reconstructing sparse symmetric block models with two blocks and connection probabilities $a/n$ and $b/n$ for inter- and intra-block edge probabilities, respectively. It was recently shown that one can do better…

Probability · Mathematics 2016-09-28 Elchanan Mossel , Joe Neeman , Allan Sly

The deletion channel takes as input a bit string $\mathbf{x} \in \{0,1\}^n$, and deletes each bit independently with probability $q$, yielding a shorter string. The trace reconstruction problem is to recover an unknown string $\mathbf{x}$…

Data Structures and Algorithms · Computer Science 2017-08-03 Yuval Peres , Alex Zhai

Variational methods that rely on a recognition network to approximate the posterior of directed graphical models offer better inference and learning than previous methods. Recent advances that exploit the capacity and flexibility in this…

Machine Learning · Computer Science 2018-02-21 R Devon Hjelm , Kyunghyun Cho , Junyoung Chung , Russ Salakhutdinov , Vince Calhoun , Nebojsa Jojic

We propose a method for jointly inferring labels across a collection of data samples, where each sample consists of an observation and a prior belief about the label. By implicitly assuming the existence of a generative model for which a…

Machine Learning · Computer Science 2022-06-22 Esther Rolf , Nikolay Malkin , Alexandros Graikos , Ana Jojic , Caleb Robinson , Nebojsa Jojic

Missing data are often dealt with multiple imputation. A crucial part of the multiple imputation process is selecting sensible models to generate plausible values for incomplete data. A method based on posterior predictive checking is…

Computation · Statistics 2026-05-14 Mingyang Cai , Stef van Buuren , Gerko Vink

DNA has immense potential as an emerging data storage medium. The principle of DNA storage is the conversion and flow of digital information between binary code stream, quaternary base, and actual DNA fragments. This process will inevitably…

Information Retrieval · Computer Science 2022-10-21 Yun Qin , Fei Zhu , Bo Xi

Resampling techniques are widely used in statistical inference and ensemble learning, in which estimators' statistical properties are essential. However, existing methods are computationally demanding, because repetitions of…

Machine Learning · Statistics 2019-05-24 Takashi Takahashi , Yoshiyuki Kabashima

The well-known trace reconstruction problem is the problem of inferring an unknown source string $x \in \{0,1\}^n$ from independent "traces", i.e. copies of $x$ that have been corrupted by a $\delta$-deletion channel which independently…

Data Structures and Algorithms · Computer Science 2022-11-08 Xi Chen , Anindya De , Chin Ho Lee , Rocco A. Servedio , Sandip Sinha

Calculation of Bayesian posteriors and model evidences typically requires numerical integration. Bayesian quadrature (BQ), a surrogate-model-based approach to numerical integration, is capable of superb sample efficiency, but its lack of…

Machine Learning · Computer Science 2023-04-11 Masaki Adachi , Satoshi Hayakawa , Martin Jørgensen , Harald Oberhauser , Michael A. Osborne

In this paper, we investigate the problem of recovering source information from an incomplete set of network coded data. We first study the theoretical performance of such systems under maximum a posteriori (MAP) decoding and derive the…

Information Theory · Computer Science 2015-03-16 Eirina Bourtsoulatze , Nikolaos Thomos , Pascal Frossard

Sequencing a DNA strand, as part of the read process in DNA storage, produces multiple noisy copies which can be combined to produce better estimates of the original strand; this is called trace reconstruction. One can reduce the error rate…

Information Theory · Computer Science 2024-08-22 Sundara Rajan Srinivasavaradhan , Sivakanth Gopi , Henry D. Pfister , Sergey Yekhanin

Statistically resolving the underlying haplotype pair for a genotype measurement is an important intermediate step in gene mapping studies, and has received much attention recently. Consequently, a variety of methods for this problem have…

Machine Learning · Computer Science 2007-10-29 Matti Kääriäinen , Niels Landwehr , Sampsa Lappalainen , Taneli Mielikäinen
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