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Related papers: OCTA-Based Biomarker Characterization in nAMD

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Objective: Ultrahigh-resolution optical coherence microscopy (OCM) has recently demonstrated its potential for accurate diagnosis of human cervical diseases. One major challenge for clinical adoption, however, is the steep learning curve…

Computer Vision and Pattern Recognition · Computer Science 2020-04-28 Yutao Ma , Tao Xu , Xiaolei Huang , Xiaofang Wang , Canyu Li , Jason Jerwick , Yuan Ning , Xianxu Zeng , Baojin Wang , Yihong Wang , Zhan Zhang , Xiaoan Zhang , Chao Zhou

Purpose: (1) To develop a deep learning algorithm to identify major tissue structures of the optic nerve head (ONH) in 3D optical coherence tomography (OCT) scans; (2) to exploit such information to robustly differentiate among healthy,…

In OCT angiography (OCTA), decorrelation computation has been widely used as a local motion index to identify dynamic flow from static tissues, but its dependence on SNR severely degrades the vascular visibility, particularly in low- SNR…

Medical Physics · Physics 2019-04-16 Luzhe Huang , Yiming Fu , Ruixiang Chen , Shanshan Yang , Haixia Qiu , Xining Wu , Shiyong Zhao , Ying Gu , Peng Li

Fast and accurate anatomical landmark detection can benefit many medical image analysis methods. Here, we propose a method to automatically detect anatomical landmarks in medical images. Automatic landmark detection is performed with a…

Computer Vision and Pattern Recognition · Computer Science 2018-04-16 Julia M. H. Noothout , Bob D. de Vos , Jelmer M. Wolterink , Tim Leiner , Ivana Išgum

In the world of medical diagnostics, the adoption of various deep learning techniques is quite common as well as effective, and its statement is equally true when it comes to implementing it into the retina Optical Coherence Tomography…

Image and Video Processing · Electrical Eng. & Systems 2022-03-03 Tasnim Sakib Apon , Mohammad Mahmudul Hasan , Abrar Islam , MD. Golam Rabiul Alam

Optical coherence tomography (OCT) is a non-invasive imaging technique with extensive clinical applications in ophthalmology. OCT enables the visualization of the retinal layers, playing a vital role in the early detection and monitoring of…

Accurate yet interpretable image-based diagnosis remains a central challenge in medical AI, particularly in settings characterized by limited data, subtle visual cues, and high-stakes clinical decision-making. Most existing vision models…

Artificial Intelligence · Computer Science 2025-12-23 Midhat Urooj , Ayan Banerjee , Sandeep Gupta

Purpose: To evaluate the sensitivity of normalized blood flow index (NBFI) for detecting early diabetic retinopathy (DR). Methods: Optical coherence tomography angiography (OCTA) images of 30 eyes from 20 healthy controls, 21 eyes of…

In recent years, there has been a growing interest in applying convolutional neural networks (CNNs) to low-level vision tasks such as denoising and super-resolution. Due to the coherent nature of the image formation process, optical…

Computer Vision and Pattern Recognition · Computer Science 2019-01-29 Ashkan Abbasi , Amirhassan Monadjemi , Leyuan Fang , Hossein Rabbani , Yi Zhang

Optical coherence tomography angiography (OCTA) is a new imaging modality to visualize retinal microvasculature and has been readily adopted in clinics. High-resolution OCT angiograms are important to qualitatively and quantitatively…

Image and Video Processing · Electrical Eng. & Systems 2023-05-11 Yuyan Ruan , Dawei Yang , Ziqi Tang , An Ran Ran , Carol Y. Cheung , Hao Chen

Early detection of cancer is crucial for treatment and overall patient survival. In the upper aerodigestive tract (UADT) the gold standard for identification of malignant tissue is an invasive biopsy. Recently, non-invasive imaging…

Computer Vision and Pattern Recognition · Computer Science 2019-10-10 Nils Gessert , Matthias Schlüter , Sarah Latus , Veronika Volgger , Christian Betz , Alexander Schlaefer

Hybrid Optical Neural Networks (ONNs, typically consisting of an optical frontend and a digital backend) offer an energy-efficient alternative to fully digital deep networks for real-time, power-constrained systems. However, their adoption…

Computer Vision and Pattern Recognition · Computer Science 2025-08-13 Jinlin Xiang , Minho Choi , Yubo Zhang , Zhihao Zhou , Arka Majumdar , Eli Shlizerman

Glaucoma, a leading cause of irreversible blindness, necessitates early detection for accurate and timely intervention to prevent irreversible vision loss. In this study, we present a novel deep learning framework that leverages the…

Image and Video Processing · Electrical Eng. & Systems 2025-09-05 Mona Ashtari-Majlan , David Masip

The estimation of glaucoma progression is a challenging task as the rate of disease progression varies among individuals in addition to other factors such as measurement variability and the lack of standardization in defining progression.…

Geographic atrophy (GA) is a key biomarker of dry age-related macular degeneration (AMD) traditionally identified through color fundus photography. Hyper-transmission defects (hyperTDs), a feature highly correlated with GA, have recently…

Quantitative Methods · Quantitative Biology 2025-11-04 Yukun Guo , An-Lun Wu , Tristan T. Hormel , Liqin Gao , Min Gao , Thomas S. Hwang , Steven T. Bailey , Yali Jia

Purpose: Disease progression of retinal atrophy associated with AMD requires the accurate quantification of the retinal atrophy changes on longitudinal OCT studies. It is based on finding, comparing, and delineating subtle atrophy changes…

Image and Video Processing · Electrical Eng. & Systems 2023-08-01 Adi Szeskin , Roei Yehuda , Or Shmueli , Jaime Levy , Leo Joskowicz

Purpose: To evaluate Pegasus-OCT, a clinical decision support software for the identification of features of retinal disease from macula OCT scans, across heterogenous populations involving varying patient demographics, device…

Image and Video Processing · Electrical Eng. & Systems 2019-07-12 Kanwal K. Bhatia , Mark S. Graham , Louise Terry , Ashley Wood , Paris Tranos , Sameer Trikha , Nicolas Jaccard

Optical Coherence Tomography (OCT) is an emerging medical imaging modality for luminal organ diagnosis. The non-constant rotation speed of optical components in the OCT catheter tip causes rotational distortion in OCT volumetric scanning.…

Optical coherence tomography (OCT) imaging is a well-known technology for visualizing retinal layers and helps ophthalmologists to detect possible diseases. Accurate and early diagnosis of common retinal diseases can prevent the patients…

Image and Video Processing · Electrical Eng. & Systems 2022-03-04 Mohammad Rahimzadeh , Mahmoud Reza Mohammadi

Histopathological analysis is crucial in artery characterization for coronary artery disease (CAD). However, histology requires an invasive and time-consuming process. In this paper, we propose to generate virtual histology staining using…

Image and Video Processing · Electrical Eng. & Systems 2022-11-15 Xueshen Li , Hongshan Liu , Xiaoyu Song , Brigitta C. Brott , Silvio H. Litovsky , Yu Gan