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Related papers: OCTA-Based Biomarker Characterization in nAMD

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In recent years, the incidence of vision-threatening eye diseases has risen dramatically, necessitating scalable and accurate screening solutions. This paper presents a comprehensive study on deep learning architectures for the automated…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Mohammad Sadegh Gholizadeh , Amir Arsalan Rezapour

Purpose: To test the feasibility of using deep learning for optical coherence tomography angiography (OCTA) detection of diabetic retinopathy (DR). Methods: A deep learning convolutional neural network (CNN) architecture VGG16 was employed…

Quantitative Methods · Quantitative Biology 2021-12-16 David Le , Minhaj Alam , Cham Yao , Jennifer I. Lim , R. V. P. Chan , Devrim Toslak , Xincheng Yao

Optical Coherence Tomography Angiography (OCTA) has been increasingly used in the management of eye and systemic diseases in recent years. Manual or automatic analysis of blood vessel in 2D OCTA images (en face angiograms) is commonly used…

Image and Video Processing · Electrical Eng. & Systems 2021-03-01 Shuai Yu , Jianyang Xie , Jinkui Hao , Yalin Zheng , Jiong Zhang , Yan Hu , Jiang Liu , Yitian Zhao

Optical coherence tomography (OCT) is one of the non-invasive and easy-to-acquire biomarkers (the thickness of the retinal layers, which is detectable within OCT scans) being investigated to diagnose Alzheimer's disease (AD). This work aims…

Image and Video Processing · Electrical Eng. & Systems 2022-06-14 Paria Jeihouni , Omid Dehzangi , Annahita Amireskandari , Ali Dabouei , Ali Rezai , Nasser M. Nasrabadi

Age-related Macular Degeneration (AMD) is the predominant cause of blindness in developed countries, specially in elderly people. Moreover, its prevalence is increasing due to the global population ageing. In this scenario, early detection…

Image and Video Processing · Electrical Eng. & Systems 2022-05-24 José Morano , Álvaro S. Hervella , José Rouco , Jorge Novo , José I. Fernández-Vigo , Marcos Ortega

Diabetic Retinopathy (DR), an ocular complication of diabetes, is a leading cause of blindness worldwide. Traditionally, DR is monitored using Color Fundus Photography (CFP), a widespread 2-D imaging modality. However, DR classifications…

Background: Patients with neovascular age-related macular degeneration (AMD) can avoid vision loss via certain therapy. However, methods to predict the progression to neovascular age-related macular degeneration (nvAMD) are lacking.…

Computer Vision and Pattern Recognition · Computer Science 2019-04-12 Boris Babenko , Siva Balasubramanian , Katy E. Blumer , Greg S. Corrado , Lily Peng , Dale R. Webster , Naama Hammel , Avinash V. Varadarajan

This study introduces a groundbreaking optical coherence tomography (OCT) imaging system dedicated for high-throughput screening applications using ex vivo tissue culture. Leveraging OCT's non-invasive, high-resolution capabilities, the…

In recent years, there has been significant development in the analysis of medical data using machine learning. It is believed that the onset of Age-related Macular Degeneration (AMD) is associated with genetic polymorphisms. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-18 Yoichi Furukawa , Satoshi Kamiya , Yoichi Sakurada , Kenji Kashiwagi , Kazuhiro Hotta

Optical Coherence Tomography (OCT) scan yields all possible cross-section images of a retina for detecting biomarkers linked to optical defects. Due to the high volume of data generated, an automated and reliable biomarker detection…

Image and Video Processing · Electrical Eng. & Systems 2025-06-03 Haz Sameen Shahgir , Tanjeem Azwad Zaman , Khondker Salman Sayeed , Md. Asif Haider , Sheikh Saifur Rahman Jony , M. Sohel Rahman

Age-related macular degeneration (AMD) is a degenerative disorder affecting the macula, a key area of the retina for visual acuity. Nowadays, it is the most frequent cause of blindness in developed countries. Although some promising…

Image and Video Processing · Electrical Eng. & Systems 2022-12-06 José Morano , Álvaro S. Hervella , José Rouco , Jorge Novo , José I. Fernández-Vigo , Marcos Ortega

Optical coherence tomography (OCT) is a medical imaging modality that allows us to probe deeper substructures of skin. The state-of-the-art wound care prediction and monitoring methods are based on visual evaluation and focus on surface…

Image and Video Processing · Electrical Eng. & Systems 2023-06-05 Prashant Kumar , Swatantra Dhara , Ayan Gope , Jyotirmoy Chatterjee , Subhamoy Mandal

The opaque nature of deep learning models remains a significant barrier to their clinical adoption in medical imaging. This paper presents a multimodal explainability framework that bridges the gap between convolutional neural network (CNN)…

Computer Vision and Pattern Recognition · Computer Science 2026-05-08 Paul Valery Nguezet , Elie Tagne Fute , Yusuf Brima , Benoit Martin Azanguezet , Marcellin Atemkeng

In ophthalmology, intravitreal operative medication therapy (IVOM) is a widespread treatment for diseases related to the age-related macular degeneration (AMD), the diabetic macular edema (DME), as well as the retinal vein occlusion (RVO).…

Image and Video Processing · Electrical Eng. & Systems 2024-10-03 Tobias Schlosser , Frederik Beuth , Trixy Meyer , Arunodhayan Sampath Kumar , Gabriel Stolze , Olga Furashova , Katrin Engelmann , Danny Kowerko

Optical Coherence Tomography (OCT) is a vital imaging modality for diagnosing and monitoring retinal diseases. However, OCT images are inherently degraded by speckle noise, which obscures fine details and hinders accurate interpretation.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-15 Botond Fazekas , Thomas Pinetz , Guilherme Aresta , Taha Emre , Hrvoje Bogunovic

Optical coherence tomography (OCT) as retina imaging technology is currently used by ophthalmologist as a non-invasive and non-contact method for diagnosis of agerelated degeneration (AMD) and diabetic macular edema (DME) diseases. Fluid…

Image and Video Processing · Electrical Eng. & Systems 2019-12-30 Elyas Rashno , Abdolreza Rashno , Sadegh Fadaei

Optical coherence tomography angiography (OCTA) is an important imaging modality in many bioengineering tasks. The image quality of OCTA, however, is often degraded by Bulk Motion Artifacts (BMA), which are due to micromotion of subjects…

Computer Vision and Pattern Recognition · Computer Science 2022-03-29 Jiaxiang Ren , Kicheon Park , Yingtian Pan , Haibin Ling

Age Related Macular Degeneration(AMD) has been one of the most leading causes of permanent vision impairment in ophthalmology. Though treatments, such as anti VEGF drugs or photodynamic therapies, were developed to slow down the…

Image and Video Processing · Electrical Eng. & Systems 2025-12-29 Daeyoung Kim

Deep learning classifiers provide the most accurate means of automatically diagnosing diabetic retinopathy (DR) based on optical coherence tomography (OCT) and its angiography (OCTA). The power of these models is attributable in part to the…

Image and Video Processing · Electrical Eng. & Systems 2023-06-28 Pengxiao Zang , Tristan T. Hormel , Jie Wang , Yukun Guo , Steven T. Bailey , Christina J. Flaxel , David Huang , Thomas S. Hwang , Yali Jia